Výsledky vyhledávání - "Crissy R. Barnas"

A Mechanistic Basis for the Beneficial Effects of Caloric Restriction On Longevity and Disease: Consequences for the Interpretation of Rodent Toxicity Studies

Autor: Ronald W. Hart, Julian E.A. Leakey, John E. Seng, Crissy R. Barnas, Vanessa M. Baker

Publikováno v: International Journal of Toxicology. 17:5-56

Caloric restriction in rodents has been repeatedly shown to increase life span while reducing the severity and retarding the onset of both spontaneous and chemically induced neoplasms. These effects of caloric restriction are associated with a spectr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ac35f8c15d78a43561332156fb6fe30b
https://doi.org/10.1177/109158189801700203

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In vivo comparison of putative probes of CYP3A4/5 activity: erythromycin, dextromethorphan, and verapamil

Autor: Irving W. Wainer, Janice B. Schwartz, Mary Ellen Krecic‐Shepard, J. Christopher Gorski, Crissy R. Barnas, Jill Slimko

Publikováno v: Clinical pharmacology and therapeutics. 66(1)

Objectives Multiple in vivo CYP3A4/5 probes have been proposed. We compared verapamil clearance measures (CYP3A4/5 substrate) to the erythromycin breath test (ERBT) and the cumulative urinary dextromethorphan/3-methoxymorphinan test. Methods Clearanc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::895f9262330afe17ea0396f968d3c6b0
https://pubmed.ncbi.nlm.nih.gov/10430108

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