Výsledky vyhledávání - "Crissey D Cameron"

Peptoid-Peptide Hybrid Analogs of the Enterococcus faecalis Fsr Auto-Inducing Peptide (AIP) Reveal Crucial Structure-Activity Relationships

Autor: Dominic N. McBrayer, Uttam Ghosh, Muralikrishna Lella, Crissey D. Cameron, Yftah Tal‐Gan

Publikováno v: Chembiochem : a European journal of chemical biology. 24(1)

As multidrug-resistant bacteria become a more pressing risk to human health, alternate approaches to treating bacterial infections are being increasingly investigated. Enterococcus faecalis is an opportunistic pathogen responsible for a large percent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e68f751802d32fe9c533bfc837f288
https://pubmed.ncbi.nlm.nih.gov/36376247

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Development and utilization of peptide-based quorum sensing modulators in Gram-positive bacteria

Autor: Dominic N McBrayer, Crissey D Cameron, Yftah Tal-Gan

Publikováno v: Org Biomol Chem

Quorum sensing (QS) is a mechanism by which bacteria regulate cell density-dependent group behaviors. Gram-positive bacteria generally rely on auto-inducing peptide (AIP)-based QS signaling to regulate their group behaviors. To develop synthetic modu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af21a89439db21990c90052aa469e647
https://europepmc.org/articles/PMC7530124/

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Rational Design of Potent Activators and Inhibitors of the Enterococcus faecalis Fsr Quorum Sensing Circuit

Autor: Brooke K Gantman, Dominic N McBrayer, Yftah Tal-Gan, Crissey D Cameron

Publikováno v: ACS Chemical Biology. 13:2673-2681

The increasing rate of resistance development to conventional antibiotics by bacteria necessitates the identification of alternative treatment possibilities that can reduce the ability of bacteria to adapt. Enterococcus faecalis remains the leading c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa13bf469d27cb8bfd58cea2af33c5a8
https://doi.org/10.1021/acschembio.8b00610

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An Entirely Solid Phase Peptide Synthesis-Based Strategy for Synthesis of Gelatinase Biosynthesis-Activating Pheromone (GBAP) Analogue Libraries: Investigating the Structure-Activity Relationships of the Enterococcus faecalis Quorum Sensing Signal

Autor: Yftah Tal-Gan, Crissey D Cameron, Brooke K Gantman, Dominic N McBrayer

Publikováno v: Organic letters. 19(12)

The development of an entirely solid-phase peptide synthesis (SPPS)-based synthesis of the quorum sensing signal gelatinase biosynthesis-activating pheromone (GBAP) from Enterococcus faecalis is reported. The method was used to prepare three librarie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5776a5f2269a2e0986a58dfca915911f
https://pubmed.ncbi.nlm.nih.gov/28590764

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