Zobrazeno 1 - 10
of 250
pro vyhledávání: '"Crispin R. Dass"'
Publikováno v:
Diabetes Epidemiology and Management, Vol 13, Iss , Pp 100183- (2024)
Aims: literature outlining the impact of diabetes on the inner ear environment and the exact etiology of diabetes-induced hearing malfunctioning is scarce. Methods: The Scopus, Pubmed and google scholar databases were used to source relevant epidemio
Externí odkaz:
https://doaj.org/article/8a8b0d0262e34ea4abdc5610c74934e8
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3991 (2024)
A novel organic–inorganic gliclazide-loaded composite bead was developed by an ionic gelation process using acidified CaCl2, chitosan and tetraethylorthosilicate (TEOS) as a crosslinker. The beads were manufactured by crosslinking an inorganic sili
Externí odkaz:
https://doaj.org/article/d6ae6a75bac948a0b129f9cb6ea00967
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2755 (2024)
Pigment epithelium-derived factor (PEDF), a serine protease inhibitor (Serpin) family member, shows promise in inhibiting tumour growth. In our study, we explored the effects of PEDF on the efficacy of the frontline chemotherapy agent doxorubicin (Do
Externí odkaz:
https://doaj.org/article/29fa8ae73ed7439d8fdda22c47ce03cb
Publikováno v:
Pharmaceutics, Vol 15, Iss 8, p 2140 (2023)
Studies have demonstrated that pigment-epithelium-derived factor (PEDF) is a robust inhibitor of tumour growth and development, implying that this may serve as a promising target for therapeutic intervention. However, the precise impact of PEDF on ca
Externí odkaz:
https://doaj.org/article/8c5a532634524813887d974c80d2603e
Autor:
Isobel C. Jones, Revathy Carnagarin, Jo Armstrong, Daphne P. L. Lin, Mia Baxter-Holland, Mina Elahy, Crispin R. Dass
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1960 (2023)
Objectives: Pigment epithelium-derived factor (PEDF) has been recently linked to insulin resistance and is capable of differentiating myocytes to bone. We examined in more detail the intricate signalling of the insulin pathway influenced by PEDF in s
Externí odkaz:
https://doaj.org/article/62ff45874fdb4699858ecc4949b6d1dc
Publikováno v:
Saudi Pharmaceutical Journal, Vol 28, Iss 3, Pp 362-368 (2020)
The antidiabetic drugs metformin, gliclazide and glipizide have been widely used and studied in terms of pharmacological and antidiabetic effects, and their individual stability has been studied in the literature. However, the drugs’ combined stabi
Externí odkaz:
https://doaj.org/article/fff61a1a9c59425d94c9c59825d594cb
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 530 (2023)
A novel gliclazide-loaded elastomeric carbohydrate pharmaceutical vehicle was successfully developed. This new siliconized alginate platform showed pseudoplastic rheology with a zeta potential ranging from (−43.8 mV to −75.5 mV). A Buchi-B390 enc
Externí odkaz:
https://doaj.org/article/1d0ed9a69bf14763bf0027433140dd4a
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 543 (2023)
Pigment epithelium-derived factor (PEDF) is a secreted glycoprotein that belongs to the serine protease inhibitor (serpin) family. An increase in PEDF activity has been shown to be a potent inhibitor of tumour progression and proliferation, suggestin
Externí odkaz:
https://doaj.org/article/7c90eddb9542406ab17e12740e5dd51a
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 15641 (2022)
Pigment epithelium-derived factor (PEDF) protein regulates normal bone, with anti-tumour roles in bone and breast cancer (BC). Pre- and post-menopausal oestrogen levels may regulate PEDF expression and function in BC, though the mechanisms behind thi
Externí odkaz:
https://doaj.org/article/8e848ca19fd941ebbb5c93654af2de0b
Autor:
Raziyeh Abooshahab, Hamidreza Ardalani, Maryam Zarkesh, Koroush Hooshmand, Ali Bakhshi, Crispin R. Dass, Mehdi Hedayati
Publikováno v:
Metabolites, Vol 12, Iss 11, p 1154 (2022)
Clinical endocrinology entails an understanding of the mechanisms involved in the regulation of tumors that occur in the endocrine system. The exact cause of endocrine cancers remains an enigma, especially when discriminating malignant lesions from b
Externí odkaz:
https://doaj.org/article/aa8828746b26441aa27dbb34a0adf88d