Immune stress suppresses innate immune signaling in preleukemic precursor B-cells to provoke leukemia in predisposed mice.

Autor: Isidro-Hernández M; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC-USAL, Campus M. de Unamuno s/n, Salamanca, Spain.; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain., Casado-García A; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC-USAL, Campus M. de Unamuno s/n, Salamanca, Spain.; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain., Oak N; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA., Alemán-Arteaga S; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC-USAL, Campus M. de Unamuno s/n, Salamanca, Spain.; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain., Ruiz-Corzo B; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC-USAL, Campus M. de Unamuno s/n, Salamanca, Spain.; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain., Martínez-Cano J; Immune system development and function Unit, Centro de Biología Molecular Severo Ochoa (Consejo Superior de Investigaciones Científicas -Universidad Autónoma de Madrid), Madrid, Spain., Mayado A; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.; Servicio de Citometría, Departamento de Medicina, Biomedical Research Networking Centre on Cancer CIBER-CIBERONC (CB16/12/00400), Institute of Health Carlos III, and Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Salamanca, Spain., Sánchez EG; Department of Pediatric Hematology and Oncology, Hospital Infantil Universitario Niño Jesús, Universidad Autónoma de Madrid, Madrid, Spain., Blanco O; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.; Departamento de Anatomía Patológica, Universidad de Salamanca, Salamanca, Spain., Gaspar ML; Immunobiology Department, Carlos III Health Institute, 28220, Majadahonda (Madrid), Spain., Orfao A; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.; Servicio de Citometría, Departamento de Medicina, Biomedical Research Networking Centre on Cancer CIBER-CIBERONC (CB16/12/00400), Institute of Health Carlos III, and Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Salamanca, Spain., Alonso-López D; Bioinformatics Unit, Cancer Research Center (CSIC-USAL), Salamanca, Spain., De Las Rivas J; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.; Bioinformatics and Functional Genomics Research Group, Cancer Research Center (CSIC-USAL), Salamanca, Spain., Riesco S; Department of Pediatrics, Hospital Universitario de Salamanca, Paseo de San Vicente, 58-182, Salamanca, 37007, Spain., Prieto-Matos P; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.; Department of Pediatrics, Hospital Universitario de Salamanca, Paseo de San Vicente, 58-182, Salamanca, 37007, Spain., González-Murillo Á; Department of Pediatric Hematology and Oncology, Hospital Infantil Universitario Niño Jesús, Universidad Autónoma de Madrid, Madrid, Spain., Criado FJG; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.; Departamento de Cirugía, , Universidad de Salamanca, Salamanca, Spain., Cenador MBG; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.; Departamento de Cirugía, , Universidad de Salamanca, Salamanca, Spain., Ramírez-Orellana M; Department of Pediatric Hematology and Oncology, Hospital Infantil Universitario Niño Jesús, Universidad Autónoma de Madrid, Madrid, Spain., de Andrés B; Immunobiology Department, Carlos III Health Institute, 28220, Majadahonda (Madrid), Spain., Vicente-Dueñas C; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain. cvd@usal.es.; Department of Pediatrics, Hospital Universitario de Salamanca, Paseo de San Vicente, 58-182, Salamanca, 37007, Spain. cvd@usal.es., Cobaleda C; Immune system development and function Unit, Centro de Biología Molecular Severo Ochoa (Consejo Superior de Investigaciones Científicas -Universidad Autónoma de Madrid), Madrid, Spain. cesar.cobaleda@csic.es., Nichols KE; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA. Kim.Nichols@STJUDE.ORG., Sánchez-García I; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC-USAL, Campus M. de Unamuno s/n, Salamanca, Spain. isg@usal.es.; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain. isg@usal.es.

Publikováno v: Nature communications [Nat Commun] 2023 Aug 24; Vol. 14 (1), pp. 5159. Date of Electronic Publication: 2023 Aug 24.

Infectious stimuli promote malignant B-cell acute lymphoblastic leukemia in the absence of AID.

Autor: Rodríguez-Hernández G; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Salamanca, Spain.; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain., Opitz FV; Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University, Moorenstrasse 5, 40225, Düsseldorf, Germany., Delgado P; B Cell Biology Lab, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain., Walter C; Institute of Medical Informatics, University of Muenster, Muenster, Germany., Álvarez-Prado ÁF; B Cell Biology Lab, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain., González-Herrero I; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Salamanca, Spain.; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain., Auer F; Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University, Moorenstrasse 5, 40225, Düsseldorf, Germany.; Department of Systems Biology, City of Hope Comprehensive Cancer Center, Monrovia, California, 91016, USA., Fischer U; Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University, Moorenstrasse 5, 40225, Düsseldorf, Germany., Janssen S; Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University, Moorenstrasse 5, 40225, Düsseldorf, Germany., Bartenhagen C; Department of Experimental Pediatric Oncology, University Children's Hospital of Cologne, Medical Faculty, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany., Raboso-Gallego J; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Salamanca, Spain.; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain., Casado-García A; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Salamanca, Spain.; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain., Orfao A; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.; Servicio de Citometría, Departamento de Medicina, CIBERON, and Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Salamanca, Spain., Blanco O; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.; Departamento de Anatomía Patológica, Universidad de Salamanca, Salamanca, Spain., Alonso-López D; Bioinformatics Unit, Cancer Research Center (CSIC-USAL), Salamanca, Spain., Rivas JL; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.; Bioinformatics and Functional Genomics Research Group, Cancer Research Center (CSIC-USAL), Salamanca, Spain., Tena-Dávila SG; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Salamanca, Spain.; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain., Müschen M; Department of Systems Biology, City of Hope Comprehensive Cancer Center, Monrovia, California, 91016, USA., Dugas M; Institute of Medical Informatics, University of Muenster, Muenster, Germany., Criado FJG; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.; Departamento de Cirugía, Universidad de Salamanca, Salamanca, Spain., Cenador MBG; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.; Departamento de Cirugía, Universidad de Salamanca, Salamanca, Spain., Vicente-Dueñas C; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain., Hauer J; Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University, Moorenstrasse 5, 40225, Düsseldorf, Germany. Julia.Hauer@med.uni-duesseldorf.de., Ramiro AR; B Cell Biology Lab, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain., Sanchez-Garcia I; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Salamanca, Spain. isg@usal.es.; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain. isg@usal.es., Borkhardt A; Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University, Moorenstrasse 5, 40225, Düsseldorf, Germany. Arndt.Borkhardt@med.uni-duesseldorf.de.

Publikováno v: Nature communications [Nat Commun] 2019 Dec 05; Vol. 10 (1), pp. 5563. Date of Electronic Publication: 2019 Dec 05.

Crebbp loss cooperates with Bcl2 overexpression to promote lymphoma in mice.

Autor: García-Ramírez I; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, Consejo Superior de Investigaciones Cientificas/Universidad de Salamanca, Campus M. de Unamuno s/n, Salamanca, Spain.; Institute of Biomedical Research of Salamanca, Salamanca, Spain., Tadros S; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE., González-Herrero I; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, Consejo Superior de Investigaciones Cientificas/Universidad de Salamanca, Campus M. de Unamuno s/n, Salamanca, Spain.; Institute of Biomedical Research of Salamanca, Salamanca, Spain., Martín-Lorenzo A; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, Consejo Superior de Investigaciones Cientificas/Universidad de Salamanca, Campus M. de Unamuno s/n, Salamanca, Spain.; Institute of Biomedical Research of Salamanca, Salamanca, Spain., Rodríguez-Hernández G; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, Consejo Superior de Investigaciones Cientificas/Universidad de Salamanca, Campus M. de Unamuno s/n, Salamanca, Spain.; Institute of Biomedical Research of Salamanca, Salamanca, Spain., Moore D; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE., Ruiz-Roca L; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, Consejo Superior de Investigaciones Cientificas/Universidad de Salamanca, Campus M. de Unamuno s/n, Salamanca, Spain.; Institute of Biomedical Research of Salamanca, Salamanca, Spain., Blanco O; Institute of Biomedical Research of Salamanca, Salamanca, Spain.; Departamento de Anatomía Patológica, Universidad de Salamanca, Salamanca, Spain., Alonso-López D; Bioinformatics Unit and., Rivas JL; Institute of Biomedical Research of Salamanca, Salamanca, Spain.; Bioinformatics and Functional Genomics Research Group, Cancer Research Center, Consejo Superior de Investigaciones Cientificas/Universidad de Salamanca, Salamanca, Spain., Hartert K; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE., Duval R; Sorbonne Paris Cité, Université Paris Diderot, Unité de Biologie Fonctionnelle et Adaptative, CNRS UMR 8251, Paris, France., Klinkebiel D; Department of Biochemistry and Molecular Biology and., Bast M; Division of Hematology/Oncology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE.; Fred and Pamela Buffett Cancer Center, Nebraska Medicine, Omaha, NE., Vose J; Division of Hematology/Oncology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE.; Fred and Pamela Buffett Cancer Center, Nebraska Medicine, Omaha, NE., Lunning M; Division of Hematology/Oncology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE.; Fred and Pamela Buffett Cancer Center, Nebraska Medicine, Omaha, NE., Fu K; Fred and Pamela Buffett Cancer Center, Nebraska Medicine, Omaha, NE.; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE., Greiner T; Fred and Pamela Buffett Cancer Center, Nebraska Medicine, Omaha, NE.; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE., Rodrigues-Lima F; Sorbonne Paris Cité, Université Paris Diderot, Unité de Biologie Fonctionnelle et Adaptative, CNRS UMR 8251, Paris, France., Jiménez R; Institute of Biomedical Research of Salamanca, Salamanca, Spain.; Departamento de Fisiología y Farmacología and., Criado FJG; Institute of Biomedical Research of Salamanca, Salamanca, Spain.; Departamento de Cirugía, Universidad de Salamanca, Salamanca, Spain., Cenador MBG; Institute of Biomedical Research of Salamanca, Salamanca, Spain.; Departamento de Cirugía, Universidad de Salamanca, Salamanca, Spain., Brindle P; Department of Biochemistry, St Jude Children's Research Hospital, Memphis, TN., Vicente-Dueñas C; Institute of Biomedical Research of Salamanca, Salamanca, Spain., Alizadeh A; Division of Oncology, Department of Medicine, Stanford University, Stanford, CA; and.; Division of Hematology/Oncology, Department of Medicine, Stanford Cancer Institute, Stanford, CA., Sánchez-García I; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, Consejo Superior de Investigaciones Cientificas/Universidad de Salamanca, Campus M. de Unamuno s/n, Salamanca, Spain.; Institute of Biomedical Research of Salamanca, Salamanca, Spain., Green MR; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE.; Fred and Pamela Buffett Cancer Center, Nebraska Medicine, Omaha, NE.

Publikováno v: Blood [Blood] 2017 May 11; Vol. 129 (19), pp. 2645-2656. Date of Electronic Publication: 2017 Mar 13.

Influence of extremely low-frequency magnetic field on the activity of antioxidant enzymes during skin wound healing in rats.

Autor: Glinka, Marek¹ (AUTHOR), Sieroń, Aleksander² (AUTHOR), Birkner, Ewa³ (AUTHOR), Cieślar, Grzegorz² (AUTHOR) cieslar1@tlen.pl

Publikováno v: Electromagnetic Biology & Medicine. Dec2013, Vol. 32 Issue 4, p463-470. 8p.

Emerging molecular subtypes and therapeutic targets in B-cell precursor acute lymphoblastic leukemia.

Autor: Li J; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China., Dai Y; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China., Wu L; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China., Zhang M; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China., Ouyang W; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China., Huang J; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. huangjy@sjtu.edu.cn.; Pôle de Recherches Sino-Français en Science du Vivant et Génomique, Laboratory of Molecular Pathology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. huangjy@sjtu.edu.cn., Chen S; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. sjchen@stn.sh.cn.; Pôle de Recherches Sino-Français en Science du Vivant et Génomique, Laboratory of Molecular Pathology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. sjchen@stn.sh.cn.

Publikováno v: Frontiers of medicine [Front Med] 2021 Jun; Vol. 15 (3), pp. 347-371. Date of Electronic Publication: 2021 Jan 05.