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Pre-transplant anti-nephrin antibodies are specific predictors of recurrent diffuse podocytopathy in the kidney allograft.

Autor: Batal I; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York, USA. Electronic address: ib2349@cumc.columbia.edu., Watts AJB; Department of Medicine, Division of Nephrology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Gibier JB; Department of Pathology, Centre Hospitalier Universitaire de Lille, Lille, France., Hamroun A; Department of Medicine, Division of Nephrology, Centre Hospitalier Universitaire de Lille, Lille, France; Department of Medicine, Division of Public Health Epidemiology, Centre Hospitalier Universitaire de Lille, Lille, France; Institut Pasteur de Lille, Inserm, University Lille, Lille, France., Top I; Insitutut d'Immunologie-HLA, Centre Hospitalier Universitaire de Lille, Lille, France., Provot F; Department of Medicine, Division of Nephrology, Centre Hospitalier Universitaire de Lille, Lille, France., Keller K; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Ye X; Department of Medicine, Division of Nephrology, Hartford Hospital, Hartford, Connecticut, USA., Fernandez HE; Department of Medicine, Division of Nephrology, Columbia University Irving Medical Center, New York, New York, USA., Leal R; Department of Medicine, Division of Nephrology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal., Andeen NK; Department of Pathology, Oregon Health & Science University, Portland, Oregon, USA., Crew RJ; Department of Medicine, Division of Nephrology, Columbia University Irving Medical Center, New York, New York, USA., Dube GK; Department of Medicine, Division of Nephrology, Columbia University Irving Medical Center, New York, New York, USA., Vasilescu ER; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York, USA., Ratner LE; Department of Surgery, Columbia University Irving Medical Center, New York, New York, USA., Bowman N; Department of Medicine, Division of Nephrology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Bomback AS; Department of Medicine, Division of Nephrology, Columbia University Irving Medical Center, New York, New York, USA., Sanna-Cherchi S; Department of Medicine, Division of Nephrology, Columbia University Irving Medical Center, New York, New York, USA., Kiryluk K; Department of Medicine, Division of Nephrology, Columbia University Irving Medical Center, New York, New York, USA., Weins A; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA. Electronic address: AWEINS@BWH.HARVARD.EDU.

Publikováno v: Kidney international [Kidney Int] 2024 Oct; Vol. 106 (4), pp. 749-752. Date of Electronic Publication: 2024 Aug 09.

Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease.

Autor: Gupta Y; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.; Institute for Inflammation Medicine, University of Lubeck, Lübeck, Germany., Friedman DJ; Nephrology Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., McNulty MT; Division of Pediatric Nephrology, Boston Children's Hospital, Boston, MA, USA.; Kidney Disease Initiative and Medical and Population Genetics Program, Broad Institute, Boston, MA, USA., Khan A; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Lane B; Division of Nephrology, Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA., Wang C; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Ke J; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Jin G; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Wooden B; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Knob AL; Nephrology Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Lim TY; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.; Unit of Genomic Variability and Complex Diseases, Department of Medical Sciences, University of Turin, Turin, Italy., Appel GB; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Huggins K; Division of Nephrology, Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA., Liu L; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Mitrotti A; Department of Precision and Regenerative Medicine and Ionian Area (DiMePre-J) Nephrology, Dialysis and Transplantation Unit, University of Bari Aldo Moro, Bari, Italy., Stangl MC; Division of Nephrology, Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA., Bomback A; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Westland R; Department of Pediatric Nephrology, Emma Children's Hospital, University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands., Bodria M; Division of Nephrology and Renal Transplantation, IRCCS Istituto Giannina Gaslini, Genoa, Italy.; Laboratory on Molecular Nephrology, IRCCS Istituto Giannina Gaslini, Genoa, Italy., Marasa M; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Shang N; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Cohen DJ; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Crew RJ; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Morello W; Pediatric Nephrology, Dialysis and Transplant Unit, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, Milano, Italy., Canetta P; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Radhakrishnan J; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Martino J; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Liu Q; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Chung WK; Departments of Pediatrics and Medicine, Columbia University Irving Medical Center, New York, NY, USA., Espinoza A; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Luo Y; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Wei WQ; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Feng Q; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Weng C; Department of Biomedical Informatics, Columbia University Irving Medical Center, New York, NY, USA., Fang Y; Department of Biomedical Informatics, Columbia University Irving Medical Center, New York, NY, USA., Kullo IJ; Atherosclerosis and Lipid Genomics Laboratory, Mayo Clinic, Rochester, MN, USA., Naderian M; Atherosclerosis and Lipid Genomics Laboratory, Mayo Clinic, Rochester, MN, USA., Limdi N; Department of Neurology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Irvin MR; Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA., Tiwari H; Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA., Mohan S; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA., Rao M; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Dube GK; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Chaudhary NS; Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA., Gutiérrez OM; Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.; Division of Nephrology, Department of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Judd SE; Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA., Cushman M; Department of Medicine and Pathology and Laboratory Medicine, University of Vermont, Burlington, VT, USA., Lange LA; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Lange EM; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Bivona DL; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Verbitsky M; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Winkler CA; Cancer Innovation Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health and Basic Research Program, Frederick National Laboratory, Frederick, MD, USA., Kopp JB; Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH, Bethesda, MD, USA., Santoriello D; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Batal I; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Pinheiro SVB; Universidade Federal de Minas Gerais (UFMG), Faculdade de Medicina, Laboratório Interdisciplinar de Investigação Médica, Departamento de Pediatria, Unidade de Nefrologia Pediátrica, Belo Horizonte, MG, Brazil., Oliveira EA; Universidade Federal de Minas Gerais (UFMG), Faculdade de Medicina, Laboratório Interdisciplinar de Investigação Médica, Departamento de Pediatria, Unidade de Nefrologia Pediátrica, Belo Horizonte, MG, Brazil., Simoes E Silva AC; Universidade Federal de Minas Gerais (UFMG), Faculdade de Medicina, Laboratório Interdisciplinar de Investigação Médica, Departamento de Pediatria, Unidade de Nefrologia Pediátrica, Belo Horizonte, MG, Brazil., Pisani I; Nephrology Unit, Parma University Hospital, and Department of Medicine and Surgery, University of Parma, Parma, Italy., Fiaccadori E; Nephrology Unit, Parma University Hospital, and Department of Medicine and Surgery, University of Parma, Parma, Italy., Lin F; Division of Pediatric Nephrology, Department of Pediatrics, Columbia University, New York, NY, USA., Gesualdo L; Department of Precision and Regenerative Medicine and Ionian Area (DiMePre-J) Nephrology, Dialysis and Transplantation Unit, University of Bari Aldo Moro, Bari, Italy., Amoroso A; Immunogenetics and Transplant Biology Service, University Hospital 'Città della Salute e della Scienza di Torino', Department of Medical Sciences, University of Turin, Turin, Italy., Ghiggeri GM; Division of Nephrology and Renal Transplantation, IRCCS Istituto Giannina Gaslini, Genoa, Italy.; Laboratory on Molecular Nephrology, IRCCS Istituto Giannina Gaslini, Genoa, Italy., D'Agati VD; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Magistroni R; Surgical, Medical and Dental Department of Morphological Sciences, Section of Nephrology, University of Modena and Reggio Emilia, Modena, Italy., Kenny EE; Institute for Genomic Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Center for Translational Genomics, Icahn School of Medicine, New York, NY, 10027, USA.; Division of Genomic Medicine, Department of Medicine, Icahn School of Medicine, New York, NY, 10027, USA., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark., Montini G; Pediatric Nephrology, Dialysis and Transplant Unit, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, Milano, Italy.; Department of Clinical Sciences and Community Health, Giuliana and Bernardo Caprotti Chair of Pediatrics, University of Milano, Milano, Italy., Hildebrandt F; Harvard Medical School, Boston, MA, USA.; Division of Pediatric Nephrology, Boston Children's Hospital, Boston, MA, USA., Paul DS; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Petrovski S; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Goldstein DB; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, USA., Kretzler M; Department of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI, USA., Gbadegesin R; Division of Nephrology, Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA., Gharavi AG; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Kiryluk K; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Sampson MG; Harvard Medical School, Boston, MA, USA.; Division of Pediatric Nephrology, Boston Children's Hospital, Boston, MA, USA.; Kidney Disease Initiative and Medical and Population Genetics Program, Broad Institute, Boston, MA, USA., Pollak MR; Nephrology Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Sanna-Cherchi S; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA. ss2517@cumc.columbia.edu.

Publikováno v: Nature communications [Nat Commun] 2023 Nov 30; Vol. 14 (1), pp. 7836. Date of Electronic Publication: 2023 Nov 30.

The pathologic spectrum of adenovirus nephritis in the kidney allograft.

Autor: Jagannathan G; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York, USA., Weins A; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Daniel E; Department of Medicine, Division of Nephrology, Columbia University Irving Medical Center, New York, New York, USA., Crew RJ; Department of Medicine, Division of Nephrology, Columbia University Irving Medical Center, New York, New York, USA., Swanson SJ; Department of Surgery, Christiana Hospital, Newark, Delaware, USA., Markowitz GS; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York, USA., D'Agati VD; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York, USA., Andeen NK; Department of Pathology, Oregon Health & Science University, Portland, Oregon, USA., Rennke HG; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Batal I; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York, USA. Electronic address: ib2349@cumc.columbia.edu.

Publikováno v: Kidney international [Kidney Int] 2023 Feb; Vol. 103 (2), pp. 378-390. Date of Electronic Publication: 2022 Nov 24.