Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Crescenzo Coppa"'
Autor:
Simona Saporiti, Tommaso Laurenzi, Uliano Guerrini, Crescenzo Coppa, Wolf Palinsky, Giulia Benigno, Luca Palazzolo, Omar Ben Mariem, Linda Montavoci, Mara Rossi, Fabio Centola, Ivano Eberini
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
Classical and accelerated molecular dynamics simulations reveal how core fucosylation in the IgG1 Fc glycan and the light chain isotype modulate the conformational behavior of the hinge and Fab domains and dynamics of IgG1 antibodies.
Externí odkaz:
https://doaj.org/article/043e09b73eb1488ea9d072900710a023
Autor:
Kelly Bugatti, Andrea Sartori, Lucia Battistini, Crescenzo Coppa, Emiel Vanhulle, Sam Noppen, Becky Provinciael, Lieve Naesens, Annelies Stevaert, Alessandro Contini, Kurt Vermeire, Franca Zanardi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8765 (2023)
Though the bulk of the COVID-19 pandemic is behind, the search for effective and safe anti-SARS-CoV-2 drugs continues to be relevant. A highly pursued approach for antiviral drug development involves targeting the viral spike (S) protein of SARS-CoV-
Externí odkaz:
https://doaj.org/article/f60413dfa7c94c51ab033a9e6be82aaf
New Chemotypes for the Inhibition of (p)ppGpp Synthesis in the Quest for New Antimicrobial Compounds
Autor:
Crescenzo Coppa, Luca Sorrentino, Monica Civera, Marco Minneci, Francesca Vasile, Sara Sattin
Publikováno v:
Molecules, Vol 27, Iss 10, p 3097 (2022)
Antimicrobial resistance (AMR) poses a serious threat to our society from both the medical and economic point of view, while the antibiotic discovery pipeline has been dwindling over the last decades. Targeting non-essential bacterial pathways, such
Externí odkaz:
https://doaj.org/article/1f1274a59fe44197b3929f2e7386b8a6
Publikováno v:
Data in Brief, Vol 12, Iss C, Pp 656-661 (2017)
This data article contains the results of docking simulations performed in order to develop a suitable in silico strategy able to assess the stability of the putative complexes between RAGE and MDA induced adducts on human albumin as experimentally d
Externí odkaz:
https://doaj.org/article/98a2fa1365874f47ba3a611b105977e6
Autor:
Marco Mol, Genny Degani, Crescenzo Coppa, Giovanna Baron, Laura Popolo, Marina Carini, Giancarlo Aldini, Giulio Vistoli, Alessandra Altomare
Publikováno v:
Redox Biology, Vol 23, Iss , Pp - (2019)
Advanced Lipoxidation End-products (ALEs) are modified proteins that can act as pathogenic factors in several chronic diseases. Several molecular mechanisms have so far been considered to explain the damaging action of ALEs and among these a pathway
Externí odkaz:
https://doaj.org/article/546fef2e2a5446dabd86d7b619b86228
Publikováno v:
Journal of Chemical Information and Modeling. 63:3030-3042
New Chemotypes for the Inhibition of (p)ppGpp Synthesis in the Quest for New Antimicrobial Compounds
Autor:
Sattin, Crescenzo Coppa, Luca Sorrentino, Monica Civera, Marco Minneci, Francesca Vasile, Sara
Publikováno v:
Molecules; Volume 27; Issue 10; Pages: 3097
Antimicrobial resistance (AMR) poses a serious threat to our society from both the medical and economic point of view, while the antibiotic discovery pipeline has been dwindling over the last decades. Targeting non-essential bacterial pathways, such
Publikováno v:
Data in Brief
Data in Brief, Vol 12, Iss C, Pp 656-661 (2017)
Data in Brief, Vol 12, Iss C, Pp 656-661 (2017)
This data article contains the results of docking simulations performed in order to develop a suitable in silico strategy able to assess the stability of the putative complexes between RAGE and MDA induced adducts on human albumin as experimentally d
Autor:
Ettore Gilardoni, Laura Blancquaert, Inge Everaert, Giancarlo Aldini, Marina Carini, Crescenzo Coppa, Luca Regazzoni, Tine Bex, Giovanna Baron, Wim Derave, Jan Stautemas, Silvia Barbaresi, Giulio Vistoli
Publikováno v:
Amino acids. 51(1)
Carnosine (beta-alanyl-L-histidine) and its methylated analogue anserine are present in relevant concentrations in the omnivore human diet. Several studies reported promising therapeutic potential for carnosine in various rodent models of oxidative s
Autor:
Giulio Vistoli, Genny Degani, Crescenzo Coppa, Marina Carini, Giancarlo Aldini, Marco Mol, Alessandra Altomare, Laura Popolo, Giovanna Baron
Publikováno v:
Redox Biology
Redox Biology, Vol 23, Iss, Pp-(2019)
Redox Biology, Vol 23, Iss, Pp-(2019)
Advanced Lipoxidation End-products (ALEs) are modified proteins that can act as pathogenic factors in several chronic diseases. Several molecular mechanisms have so far been considered to explain the damaging action of ALEs and among these a pathway