The crystal structures of TrkA and TrkB suggest key regions for achieving selective inhibition.

Autor: Bertrand T; Department of Structure, Design, and Informatics, Sanofi, 13 Quai Jules Guesde, Vitry-sur-Seine, 94403 Cedex, France. thomas.bertrand@sanofi.com, Kothe M, Liu J, Dupuy A, Rak A, Berne PF, Davis S, Gladysheva T, Valtre C, Crenne JY, Mathieu M

Publikováno v: Journal of molecular biology [J Mol Biol] 2012 Oct 26; Vol. 423 (3), pp. 439-53. Date of Electronic Publication: 2012 Aug 16.