Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Creighton T. Tuzon"'
Autor:
Creighton T. Tuzon, Tanya Spektor, Xiaodong Kong, Lauren M. Congdon, Shumin Wu, Gunnar Schotta, Kyoko Yokomori, Judd C. Rice
Publikováno v:
Cell Reports, Vol 8, Iss 2, Pp 430-438 (2014)
Although selective binding of 53BP1 to dimethylated histone H4 lysine 20 (H4K20me2) at DNA double-strand breaks (DSBs) is a necessary and pivotal determinant of nonhomologous end joining (NHEJ)-directed repair, the enzymes that generate H4K20me2 at D
Externí odkaz:
https://doaj.org/article/ec95bf93338f4bc69b65aa395da18533
Autor:
Jacqueline K. Dawson, E T. Schroeder, Christianne J. Lane, Christina M. Dieli-Conwright, Judd C. Rice, Tanya B. Dorff, Mitchell E. Gross, Creighton T. Tuzon
Publikováno v:
Integrative Cancer Therapies
Integrative Cancer Therapies, Vol 20 (2021)
Integrative Cancer Therapies, Vol 20 (2021)
Purpose: Prostate cancer survivors (PCS) receive androgen deprivation therapy (ADT) as treatment for recurrent cancer, yet ADT is associated with loss of skeletal muscle and physical function. Resistance training can counter both muscle and physical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::009d7900ef83e27b148a404aff612a57
http://europepmc.org/articles/PMC8312192
http://europepmc.org/articles/PMC8312192
Publikováno v:
Human Molecular Genetics. 26:3253-3270
Fibroblast Growth Factor (FGF) signaling promotes self-renewal in progenitor cells by encouraging proliferation and inhibiting cellular senescence. Yet, these beneficial effects can be hijacked by disease-causing mutations in FGF receptor (FGFR) duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b80b2856af9c4a5f9d55e719ae7c50
https://doi.org/10.1093/hmg/ddx209
https://doi.org/10.1093/hmg/ddx209
Autor:
Gary G. Chiang, Masoud Vedadi, Alberto Martin, Dalia Barsyte-Lovejoy, William N. Pappano, Cheryl H. Arrowsmith, Alexander Nuber, Vijayaratnam Santhakumar, Kenneth M. Comess, Judd C. Rice, Maricel Torrent, Gunnar Schotta, Peter Brown, Conglei Li, Anup K. Upadhyay, Fengling Li, Alex R Shoemaker, Ramzi F. Sweis, Mikkel Algire, Yujia Dai, Loren M. Lasko, Taylor R H Mitchell, Creighton T. Tuzon, Kenneth D. Bromberg, Mohammad S. Eram, Michael R. Michaelides, Niru B. Soni, Clarissa G. Jakob, Chaohong Sun, Manisha A Jhala, Vlasios Manaves
Publikováno v:
Nature Chemical Biology. 13:317-324
Protein lysine methyltransferases (PKMTs) regulate diverse physiological processes including transcription and the maintenance of genomic integrity. Genetic studies suggest that the PKMTs SUV420H1 and SUV420H2 facilitate proficient nonhomologous end-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa83d9f95eebf4a7288c158fbe1c7aaf
https://doi.org/10.1038/nchembio.2282
https://doi.org/10.1038/nchembio.2282
Publikováno v:
Curr Osteoporos Rep
Fibroblast growth factor receptor (FGFR) signaling regulates proliferation and differentiation during development and homeostasis. While membrane-bound FGFRs play a central role in these processes, the function of nuclear FGFRs is also critical. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cdba705ec9f88dc5b6a8bf8ccd7bb48
https://europepmc.org/articles/PMC8221190/
https://europepmc.org/articles/PMC8221190/
Autor:
Amy E. Merrill, Camilla S Teng, Deepanwita Pal, Ryan R. Roberts, Ronen Schweitzer, Creighton T. Tuzon, Lauren Bobzin
Publikováno v:
Development
Tendon and bone are attached by a transitional connective tissue that is morphologically graded from tendinous to osseous and develops from bipotent progenitors that co-express scleraxis (Scx) and Sox9 (Scx(+)/Sox9(+)). Scx(+)/Sox9(+) progenitors hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::956f9673674b2b3045a82bc0692cfe75
https://doi.org/10.1242/dev.170241
https://doi.org/10.1242/dev.170241
The marketing approvals of medical products based on regenerative technologies will depend on data collected from clinical trials that are designed to evaluate the safety and efficacy of an investigational product. Most of what we know about clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e98530835975ffcf27fae994c5c3be6
https://doi.org/10.1016/b978-0-12-801238-3.65584-8
https://doi.org/10.1016/b978-0-12-801238-3.65584-8
Autor:
Judd C. Rice, Lauren M. Congdon, Kyoko Yokomori, Xiaodong Kong, Gunnar Schotta, Shumin Wu, Creighton T. Tuzon, Tanya M. Spektor
Publikováno v:
Cell Reports, Vol 8, Iss 2, Pp 430-438 (2014)
Cell reports, vol 8, iss 2
Tuzon, CT; Spektor, T; Kong, X; Congdon, LM; Wu, S; Schotta, G; et al.(2014). Concerted Activities of Distinct H4K20 Methyltransferases at DNA Double-Strand Breaks Regulate 53BP1 Nucleation and NHEJ-Directed Repair. Cell Reports, 8(2), 430-438. doi: 10.1016/j.celrep.2014.06.013. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8j4860p6
Cell reports, vol 8, iss 2
Tuzon, CT; Spektor, T; Kong, X; Congdon, LM; Wu, S; Schotta, G; et al.(2014). Concerted Activities of Distinct H4K20 Methyltransferases at DNA Double-Strand Breaks Regulate 53BP1 Nucleation and NHEJ-Directed Repair. Cell Reports, 8(2), 430-438. doi: 10.1016/j.celrep.2014.06.013. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8j4860p6
Although selective binding of 53BP1 to dimethylated histone H4 lysine 20 (H4K20me2) at DNA double-strand breaks (DSBs) is a necessary and pivotal determinant of nonhomologous end joining (NHEJ)-directed repair, the enzymes that generate H4K20me2 at D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817f63953652abdbf9c40c4cef5ca962
http://www.sciencedirect.com/science/article/pii/S2211124714004811
http://www.sciencedirect.com/science/article/pii/S2211124714004811
Changes in ribosome biogenesis are tightly linked to cell growth, proliferation, and differentiation. The rate of ribosome biogenesis is established by RNA Pol I-mediated transcription of ribosomal RNA (rRNA). Thus, rRNA gene transcription is a key d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05bc43540428a7b2afcf178927aeb581
https://europepmc.org/articles/PMC5382099/
https://europepmc.org/articles/PMC5382099/
Publikováno v:
Yeast. 24:39-45
Epitope tagging permits the detection of proteins when protein-specific antibodies are not available. However, the epitope tag can reduce the function of the tagged protein. Here we describe a cassette that can be used to introduce an eight amino aci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a9e3976bf42ed3652f488f498cd6310
https://doi.org/10.1002/yea.1431
https://doi.org/10.1002/yea.1431