Recombinant chimeric horsepox virus (TNX-801) is attenuated relative to vaccinia virus strains in both in vitro and in vivo models.

Autor: Trefry SV; Discovery and Translations Sciences, Tonix Pharmaceuticals, Frederick, Maryland, USA., Awasthi M; Discovery and Translations Sciences, Tonix Pharmaceuticals, Frederick, Maryland, USA., Raney CN; Discovery and Translations Sciences, Tonix Pharmaceuticals, Frederick, Maryland, USA., Cregger AL; Discovery and Translations Sciences, Tonix Pharmaceuticals, Frederick, Maryland, USA., Gonzales CA; Discovery and Translations Sciences, Tonix Pharmaceuticals, Frederick, Maryland, USA., Layton BL; Discovery and Translations Sciences, Tonix Pharmaceuticals, Frederick, Maryland, USA., Enamorado RN; Discovery and Translations Sciences, Tonix Pharmaceuticals, Frederick, Maryland, USA., Martinez NA; Discovery and Translations Sciences, Tonix Pharmaceuticals, Frederick, Maryland, USA., Gohegan DS; Discovery and Translations Sciences, Tonix Pharmaceuticals, Frederick, Maryland, USA., Masoud-Bahnamiri M; Discovery and Translations Sciences, Tonix Pharmaceuticals, Frederick, Maryland, USA., Cho JY; Discovery and Translations Sciences, Tonix Pharmaceuticals, Frederick, Maryland, USA., Myscofski DM; Discovery and Translations Sciences, Tonix Pharmaceuticals, Frederick, Maryland, USA., Moulaei T; Discovery and Translations Sciences, Tonix Pharmaceuticals, Frederick, Maryland, USA., Ziółkowska NE; Discovery and Translations Sciences, Tonix Pharmaceuticals, Frederick, Maryland, USA., Goebel SJ; Discovery and Translations Sciences, Tonix Pharmaceuticals, Frederick, Maryland, USA., Lederman S; Discovery and Translations Sciences, Tonix Pharmaceuticals, Frederick, Maryland, USA., Bavari S; Discovery and Translations Sciences, Tonix Pharmaceuticals, Frederick, Maryland, USA., Nasar F; Discovery and Translations Sciences, Tonix Pharmaceuticals, Frederick, Maryland, USA.

Publikováno v: MSphere [mSphere] 2024 Nov 13, pp. e0026524. Date of Electronic Publication: 2024 Nov 13.