Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Creg Darby"'
Autor:
Yi-Cheng Sun, Alexandra Koumoutsi, Clayton Jarrett, Kevin Lawrence, Frank C Gherardini, Creg Darby, B Joseph Hinnebusch
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19267 (2011)
Yersinia pestis forms a biofilm in the foregut of its flea vector that promotes transmission by flea bite. As in many bacteria, biofilm formation in Y. pestis is controlled by intracellular levels of the bacterial second messenger c-di-GMP. Two Y. pe
Externí odkaz:
https://doaj.org/article/c1ebd5439b11413e901d1ce9a6f7fee4
Autor:
John M Chaston, Garret Suen, Sarah L Tucker, Aaron W Andersen, Archna Bhasin, Edna Bode, Helge B Bode, Alexander O Brachmann, Charles E Cowles, Kimberly N Cowles, Creg Darby, Limaris de Léon, Kevin Drace, Zijin Du, Alain Givaudan, Erin E Herbert Tran, Kelsea A Jewell, Jennifer J Knack, Karina C Krasomil-Osterfeld, Ryan Kukor, Anne Lanois, Phil Latreille, Nancy K Leimgruber, Carolyn M Lipke, Renyi Liu, Xiaojun Lu, Eric C Martens, Pradeep R Marri, Claudine Médigue, Megan L Menard, Nancy M Miller, Nydia Morales-Soto, Stacie Norton, Jean-Claude Ogier, Samantha S Orchard, Dongjin Park, Youngjin Park, Barbara A Qurollo, Darby Renneckar Sugar, Gregory R Richards, Zoé Rouy, Brad Slominski, Kathryn Slominski, Holly Snyder, Brian C Tjaden, Ransome van der Hoeven, Roy D Welch, Cathy Wheeler, Bosong Xiang, Brad Barbazuk, Sophie Gaudriault, Brad Goodner, Steven C Slater, Steven Forst, Barry S Goldman, Heidi Goodrich-Blair
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27909 (2011)
Members of the genus Xenorhabdus are entomopathogenic bacteria that associate with nematodes. The nematode-bacteria pair infects and kills insects, with both partners contributing to insect pathogenesis and the bacteria providing nutrition to the nem
Externí odkaz:
https://doaj.org/article/601a8f7e75314ec7ad543f2dd7700160
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6741 (2009)
The cuticle of Caenorhabditis elegans, a complex, multi-layered extracellular matrix, is a major interface between the animal and its environment. Biofilms produced by the bacterial genus Yersinia attach to the cuticle of the worm, providing an assay
Externí odkaz:
https://doaj.org/article/59a85b9008bd4becb5da1784d4011be9
Publikováno v:
Proceedings of the National Academy of Sciences. 105:8097-8101
Yersinia pestis , the agent of bubonic plague, evolved from the enteric pathogen Yersinia pseudotuberculosis within the past 20,000 years. Because ancestor and descendant both exist, it is possible to infer steps in molecular evolution by direct expe
Publikováno v:
Biological Control. 38:22-46
Two phylogenetically distinct groups of the entomopathogenic nematodes, Heterorhabditis and Steinernema, are vectors for enteric insect pathogenic bacteria, Photorhabdus Boemare et al., spp. and Xenorhabdus Poinar and Thomas spp., respectively. The g
Publikováno v:
Infection and Immunity. 73:7236-7242
Yersinia pestis , the cause of bubonic plague, blocks feeding by its vector, the flea. Recent evidence indicates that blockage is mediated by an in vivo biofilm. Y. pestis and the closely related Yersinia pseudotuberculosis also make biofilms on the
Autor:
Creg Darby, Li Tan
Publikováno v:
Journal of Bacteriology. 186:5087-5092
Bubonic plague is transmitted by fleas whose feeding is blocked by a mass of Yersinia pestis in the digestive tract. Y. pestis and the closely related Y. pseudotuberculosis also block the feeding of Caenorhabditis elegans by forming a biofilm on the
Autor:
Patricia M. Berninsone, Brian J. Libby, Maria J. Gravato-Nobre, Carlos B. Hirschberg, Christine Göbel, Jörg Höflich, Jonathan Hodgkin, Ralf Baumeister, Samuel M. Politz, Creg Darby
Publikováno v:
Journal of Biological Chemistry. 279:30440-30448
During the establishment of a bacterial infection, the surface molecules of the host organism are of particular importance, since they mediate the first contact with the pathogen. In Caenorhabditis elegans, mutations in the srf-3 locus confer resista
Autor:
Creg Darby, Stanley Falkow
Publikováno v:
Infection and Immunity. 69:6271-6275
Pathogens produce virulence factors that interact directly with host molecules, but in many cases the host targets are unknown. The genetic and molecular identification of these orphan targets is often not feasible with mammalian experimental models.
Publikováno v:
Proceedings of the National Academy of Sciences. 96:15202-15207
Identification of host factors that interact with pathogens is crucial to an understanding of infectious disease, but direct screening for host mutations to aid in this task is not feasible in mammals. The nematode Caenorhabditis elegans is a genetic