Fluoroquinolones and isoniazid resistant TB: implications for the 2018 WHO guidance

Autor: Stagg, HR, Bothamley, GH, Davidson, JA, Kunst, H, Lalor, MK, Lipman, MC, Loutet, MG, Lozewicz, S, Mohiyuddin, T, Abbara, A, Alexander, E, Booth, H, Creer, DD, Harris, RJ, Kon, OM, Loebinger, MR, McHugh, TD, Milburn, HJ, Palchaudhuri, P, Phillips, PPJ, Schmok, E, Taylor, L, Abubakar, I, on behalf of the London INH-R TB study group

Publikováno v: Stagg, HR, Bothamley, GH, Davidson, JA, Kunst, H, Lalor, MK, Lipman, MC, Loutet, MG, Lozewicz, S, Mohiyuddin, T, Abbara, A, Alexander, E, Booth, H, Creer, DD, Harris, RJ, Kon, OM, Loebinger, MR, McHugh, TD, Milburn, HJ, Palchaudhuri, P, Phillips, PPJ, Schmok, E, Taylor, L, Abubakar, I & on behalf of the London INH-R TB study group 2019, ' Fluoroquinolones and isoniazid resistant TB: implications for the 2018 WHO guidance ', European Respiratory Journal . https://doi.org/10.1183/13993003.00982-2019

INTRODUCTION: 2018 World Health Organization (WHO) guidelines for the treatment of isoniazid (H) resistant (Hr) tuberculosis recommend a four-drug regimen- rifampicin (R), ethambutol (E), pyrazinamide (Z) and levofloxacin (Lfx)- with or without H ([H

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