Zobrazeno 1 - 10
of 2 633
pro vyhledávání: '"Cre-LoxP"'
Autor:
Toshihide Mizoguchi
Publikováno v:
Japanese Dental Science Review, Vol 60, Iss , Pp 109-119 (2024)
Bone tissue provides structural support for our bodies, with the inner bone marrow (BM) acting as a hematopoietic organ. Within the BM tissue, two types of stem cells play crucial roles: mesenchymal stem cells (MSCs) (or skeletal stem cells) and hema
Externí odkaz:
https://doaj.org/article/cb6b5dfa805441a6ba35a2adcc717353
Autor:
Kumi Morikawa, Akira Nagasaki, Lue Sun, Eihachiro Kawase, Tatsuhiko Ebihara, Yasuaki Shirayoshi
Publikováno v:
FEBS Open Bio, Vol 14, Iss 11, Pp 1888-1898 (2024)
Establishing a highly efficient photoactivatable Cre recombinase PA‐Cre3.0 can allow spatiotemporal control of Cre recombinase activity. This technique may help to elucidate cell lineages, as well as facilitate gene and cell function analysis durin
Externí odkaz:
https://doaj.org/article/fea6750b912349d096dcb4d2e9258167
Autor:
Amanda Davenport, Chase W. Kessinger, Ryan D. Pfeiffer, Nikita Shah, Richard Xu, E. Dale Abel, Nathan R. Tucker, Zhiqiang Lin
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 9, Iss , Pp 100081- (2024)
We have previously shown that the Myh6 promoter drives Cre expression in a subset of male germ line cells in three independent Myh6-Cre mouse lines, including two transgenic lines and one knock-in allele. In this study, we further compared the tissue
Externí odkaz:
https://doaj.org/article/939b965e49d341b48bd2b18c3a47eca5
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Microbial communities in the human gut play a significant role in regulating host gene expression, influencing a variety of biological processes. To understand the molecular mechanisms underlying host-microbe interactions, tools that can dissect sign
Externí odkaz:
https://doaj.org/article/7765730e6d9941f8b252047733ff7a20
The aryl hydrocarbon receptor in β-cells mediates the effects of TCDD on glucose homeostasis in mice
Autor:
Myriam P. Hoyeck, Ma. Enrica Angela Ching, Lahari Basu, Kyle van Allen, Jana Palaniyandi, Ineli Perera, Emilia Poleo-Giordani, Antonio A. Hanson, Peyman Ghorbani, Morgan D. Fullerton, Jennifer E. Bruin
Publikováno v:
Molecular Metabolism, Vol 81, Iss , Pp 101893- (2024)
Objective: Chronic exposure to persistent organic pollutants (POPs) is associated with increased incidence of type 2 diabetes, hyperglycemia, and poor insulin secretion in humans. Dioxins and dioxin-like compounds are a broad class of POPs that exert
Externí odkaz:
https://doaj.org/article/5118b2da76354e0c9b01b46be2a881b9
Autor:
Giusy Tornillo, Lauren Warrington, Howard Kendrick, Adam T. Higgins, Trevor Hay, Sam Beck, Matthew J. Smalley
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/48df8545687f444d83f560c04bbf5e5a
Publikováno v:
Frontiers in Hematology, Vol 2 (2024)
IntroductionEKLF/Klf1 is a tissue-restricted transcription factor that plays a critical role in all aspects of erythropoiesis. Of particular note is its tissue-restricted pattern of expression, a property that could prove useful for expression contro
Externí odkaz:
https://doaj.org/article/ab3691a129df458cabf86927def746e6
Autor:
Naoto Sambe, Masaharu Yoshihara, Teppei Nishino, Ryosuke Sugiura, Takahiro Nakayama, Chandra Louis, Satoru Takahashi
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-8 (2023)
Abstract Objective A mammalian Delta-Notch signaling component, Notch1, has been suggested for its expression during the normal sperm development although its conditional deletion caused no apparent abnormalities. Since we established our original tr
Externí odkaz:
https://doaj.org/article/770f38d900274e69a599aaf7efe5b9b5
Autor:
Nan-Kai Wang, Pei-Kang Liu, Yang Kong, Yun-Ju Tseng, Laura A. Jenny, Nicholas D. Nolan, Nelson Chen, Hung-Hsi Wang, Chun Wei Hsu, Wan-Chun Huang, Janet R. Sparrow, Chyuan-Sheng Lin, Stephen H. Tsang
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Background Cones are essential for color recognition, high resolution, and central vision; therefore cone death causes blindness. Understanding the pathophysiology of each cell type in the retina is key to developing therapies for retinal di
Externí odkaz:
https://doaj.org/article/f06c541ff511434ab196ba88974fd001
Autor:
Ryosuke Sugiura, Takahiro Nakayama, Teppei Nishino, Naoto Sambe, Freddy Radtke, Masaharu Yoshihara, Satoru Takahashi
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-6 (2023)
Abstract Objective A Delta-Notch signaling component, Notch1, is involved in the normal development and multiple disorders of the kidney. Although the increase in Notch1 signaling is crucial to these pathogeneses, the basal signaling level in ‘heal
Externí odkaz:
https://doaj.org/article/7c1bf0cc20784688bc9b986e9d750616