Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Crd1, cardiolipin synthase"'
Autor:
Paulína Káňovičová, Petra Čermáková, Dominika Kubalová, Lenka Bábelová, Petra Veselá, Martin Valachovič, Jakub Zahumenský, Anton Horváth, Jan Malínský, Mária Balážová
Publikováno v:
The Journal of Biological Chemistry
Barth syndrome (BTHS) is an inherited mitochondrial disorder characterized by a decrease in total cardiolipin and the accumulation of its precursor monolysocardiolipin due to the loss of the transacylase enzyme tafazzin. However, the molecular basis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde4a52087aa3b610bb0be1c6a81a9d6
https://doi.org/10.1016/j.jbc.2021.101462
https://doi.org/10.1016/j.jbc.2021.101462
Autor:
Thomas Kleinschroth, Nikolaus Pfanner, Günther Daum, Susanne E. Horvath, Lena Böttinger, Thomas Becker, Carola Hunte
Publikováno v:
Journal of Molecular Biology
The mitochondrial inner membrane contains two non-bilayer‐forming phospholipids, phosphatidylethanolamine (PE) and cardiolipin (CL). Lack of CL leads to destabilization of respiratory chain supercomplexes, a reduced activity of cytochrome c oxidase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc99418abf13d2262153b353a2ac15ca
https://doi.org/10.1016/j.jmb.2012.09.001
https://doi.org/10.1016/j.jmb.2012.09.001