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CDK1 is up-regulated by temozolomide in an NF-κB dependent manner in glioblastoma.

Autor: Voce DJ; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, IL, 60637, USA.; Department of Neurosurgery, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Bernal GM; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, IL, 60637, USA., Cahill KE; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, IL, 60637, USA., Wu L; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, IL, 60637, USA., Mansour N; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, IL, 60637, USA., Crawley CD; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, IL, 60637, USA., Campbell PS; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, IL, 60637, USA., Arina A; Department of Radiation and Cellular Oncology, The Ludwig Center for Metastasis Research, The University of Chicago, Chicago, IL, 60637, USA., Weichselbaum RR; Department of Radiation and Cellular Oncology, The Ludwig Center for Metastasis Research, The University of Chicago, Chicago, IL, 60637, USA., Yamini B; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, IL, 60637, USA. byamini@surgery.bsd.uchicago.edu.

Publikováno v: Scientific reports [Sci Rep] 2021 Mar 11; Vol. 11 (1), pp. 5665. Date of Electronic Publication: 2021 Mar 11.

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Akademický článek

p50 mono-ubiquitination and interaction with BARD1 regulates cell cycle progression and maintains genome stability.

Autor: Wu L; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, IL, 60637, USA., Crawley CD; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, IL, 60637, USA., Garofalo A; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, IL, 60637, USA., Nichols JW; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, IL, 60637, USA., Campbell PA; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, IL, 60637, USA., Khramtsova GF; Department of Medicine, The University of Chicago, Chicago, IL, 60637, USA., Olopade OI; Department of Medicine, The University of Chicago, Chicago, IL, 60637, USA., Weichselbaum RR; Department of Radiation and Cellular Oncology, and The Ludwig Center for Metastasis Research, The University of Chicago, Chicago, IL, 60637, USA., Yamini B; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, IL, 60637, USA. byamini@surgery.bsd.uchicago.edu.

Publikováno v: Nature communications [Nat Commun] 2020 Oct 06; Vol. 11 (1), pp. 5007. Date of Electronic Publication: 2020 Oct 06.

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Akademický článek

DDX39B interacts with the pattern recognition receptor pathway to inhibit NF-κB and sensitize to alkylating chemotherapy.

Autor: Szymura SJ; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, IL, 60637, USA., Bernal GM; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, IL, 60637, USA., Wu L; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, IL, 60637, USA., Zhang Z; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, IL, 60637, USA., Crawley CD; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, IL, 60637, USA., Voce DJ; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, IL, 60637, USA., Campbell PA; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, IL, 60637, USA., Ranoa DE; Department of Radiation and Cellular Oncology, and The Ludwig Center for Metastasis Research, The University of Chicago, Chicago, IL, 60637, USA., Weichselbaum RR; Department of Radiation and Cellular Oncology, and The Ludwig Center for Metastasis Research, The University of Chicago, Chicago, IL, 60637, USA., Yamini B; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, IL, 60637, USA. byamini@surgery.bsd.uchicago.edu.

Publikováno v: BMC biology [BMC Biol] 2020 Mar 24; Vol. 18 (1), pp. 32. Date of Electronic Publication: 2020 Mar 24.

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Akademický článek

Temozolomide Treatment Induces lncRNA MALAT1 in an NF-κB and p53 Codependent Manner in Glioblastoma.

Autor: Voce DJ; Department of Neurosurgery, Vanderbilt University Medical Center, Nashville, Tennessee., Bernal GM; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, Illinois., Wu L; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, Illinois., Crawley CD; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, Illinois., Zhang W; Department of Preventative Medicine, Northwestern University, Chicago, Illinois., Mansour NM; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, Illinois., Cahill KE; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, Illinois., Szymura SJ; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, Illinois., Uppal A; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, Illinois., Raleigh DR; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, Illinois., Spretz R; LNK Chemsolutions LLC, Lincoln, Nebraska., Nunez L; LNK Chemsolutions LLC, Lincoln, Nebraska., Larsen G; LNK Chemsolutions LLC, Lincoln, Nebraska., Khodarev NN; Department of Radiation and Cellular Oncology, and The Ludwig Center for Metastasis Research, The University of Chicago, Chicago, Illinois., Weichselbaum RR; Department of Radiation and Cellular Oncology, and The Ludwig Center for Metastasis Research, The University of Chicago, Chicago, Illinois., Yamini B; Department of Surgery, Section of Neurosurgery, The University of Chicago, Chicago, Illinois. byamini@surgery.bsd.uchicago.edu.

Publikováno v: Cancer research [Cancer Res] 2019 May 15; Vol. 79 (10), pp. 2536-2548. Date of Electronic Publication: 2019 Apr 02.

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Akademický článek

Nfkb1 is a haploinsufficient DNA damage-specific tumor suppressor.

Autor: Voce DJ; Section of Neurosurgery, The University of Chicago, Chicago, IL, USA., Schmitt AM; Section of Neurosurgery, The University of Chicago, Chicago, IL, USA., Uppal A; Section of General Surgery, Department of Surgery, The University of Chicago, Chicago, IL, USA., McNerney ME; Institute for Genomics and Systems Biology, Department of Pathology, The University of Chicago, Chicago, IL, USA., Bernal GM; Section of Neurosurgery, The University of Chicago, Chicago, IL, USA., Cahill KE; Section of Neurosurgery, The University of Chicago, Chicago, IL, USA., Wahlstrom JS; Section of Neurosurgery, The University of Chicago, Chicago, IL, USA., Nassiri A; Section of Neurosurgery, The University of Chicago, Chicago, IL, USA., Yu X; Section of Neurosurgery, The University of Chicago, Chicago, IL, USA., Crawley CD; Section of Neurosurgery, The University of Chicago, Chicago, IL, USA., White KP; Institute for Genomics and Systems Biology, Department of Human Genetics, The University of Chicago, Chicago, IL, USA., Onel K; Department of Pediatrics, The University of Chicago, Chicago, IL, USA., Weichselbaum RR; Department of Radiation and Cellular Oncology, and Ludwig Center for Metastasis Research, The University of Chicago, Chicago, IL, USA., Yamini B; Section of Neurosurgery, The University of Chicago, Chicago, IL, USA.

Publikováno v: Oncogene [Oncogene] 2015 May 21; Vol. 34 (21), pp. 2807-13. Date of Electronic Publication: 2014 Jul 21.

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