Výsledky vyhledávání - "Crawford Erin L"

Akademický článek

Stable low-level expression of p21WAF1/CIP1 in A549 human bronchogenic carcinoma cell line-derived clones down-regulates E2F1 mRNA and restores cell proliferation control

Autor: Crawford Erin L, Harr Michael W, Graves Timothy G, Willey James C

Publikováno v: Molecular Cancer, Vol 5, Iss 1, p 1 (2006)

Abstract Background Deregulated cell cycle progression and loss of proliferation control are key properties of malignant cells. In previous studies, an interactive transcript abundance index (ITAI) comprising three cell cycle control genes, [MYC × E

Externí odkaz: https://doaj.org/article/986ba5e0cc2044b5ba4182095c6b179c

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Akademický článek

CEBPG transcription factor correlates with antioxidant and DNA repair genes in normal bronchial epithelial cells but not in individuals with bronchogenic carcinoma

Autor: Yoon Youngsook, Hernandez Dawn-Alita, Khuder Sadik A, Crawford Erin L, Mullins D'Anna N, Willey James C

Publikováno v: BMC Cancer, Vol 5, Iss 1, p 141 (2005)

Abstract Background Cigarette smoking is the primary cause of bronchogenic carcinoma (BC), yet only 10–15% of heavy smokers develop BC and it is likely that this variation in risk is, in part, genetically determined. We previously reported a set of

Externí odkaz: https://doaj.org/article/c11b8105e66d4663a1609d1744062910

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Akademický článek

Variation in transcriptional regulation of cyclin dependent kinase inhibitor p21waf1/cip1 among human bronchogenic carcinomas

Autor: Reed Cheryl AM, Warner Kristy A, Crawford Erin L, Graves Timothy G, Harr Michael W, Willey James C

Publikováno v: Molecular Cancer, Vol 4, Iss 1, p 23 (2005)

Abstract Background Cell proliferation control depends in part on the carefully ordered regulation of transcription factors. The p53 homolog p73, contributes to this control by directly upregulating the cyclin dependent kinase inhibitor, p21waf1/cip1

Externí odkaz: https://doaj.org/article/920ba0b1420d4c61a67662021dca1329

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Akademický článek

ABCC5, ERCC2, XPA and XRCC1 transcript abundance levels correlate with cisplatin chemoresistance in non-small cell lung cancer cell lines

Autor: Khuder Sadik A, Elkhairi Fadel, Warner Kristy A, Crawford Erin L, Weaver David A, Willey James C

Publikováno v: Molecular Cancer, Vol 4, Iss 1, p 18 (2005)

Abstract Background Although 40–50% of non-small cell lung cancer (NSCLC) tumors respond to cisplatin chemotherapy, there currently is no way to prospectively identify potential responders. The purpose of this study was to determine whether transcr

Externí odkaz: https://doaj.org/article/00aa0c1199f24f87bfea799989c7fd78

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