Paralogue-Selective Degradation of the Lysine Acetyltransferase EP300

Autor: Chen, Xuemin, Crawford, McKenna C., Xiong, Ying, Shaik, Anver Basha, Suazo, Kiall F., Bauer, Ludwig G., Penikalapati, Manini S., Williams, Joycelyn H., Huber, Kilian V. M., Andressen, Thorkell, Swenson, Rolf E., Meier, Jordan L.

Publikováno v: JACS Au; August 2024, Vol. 4 Issue: 8 p3094-3103, 10p

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Transfer RNA acetylation regulates in vivo mammalian stress signaling.

Autor: Gamage ST; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA., Khoogar R; RNA Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA., Manage SH; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA., Crawford MC; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA., Georgeson J; Department of Molecular Genetics, Weizmann Institute of Science Rehovot 76100, Israel., Polevoda BV; Department of Biochemistry and Biophysics, Center for RNA Biology, School of Medicine and Dentistry, University of Rochester, Rochester, NY, USA., Sanders C; Animal Research Technical Support, Laboratory Animal Sciences Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Lee KA; Animal Research Technical Support, Laboratory Animal Sciences Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Nance KD; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA., Iyer V; Department of Molecular Genetics, Weizmann Institute of Science Rehovot 76100, Israel., Kustanovich A; Department of Molecular Genetics, Weizmann Institute of Science Rehovot 76100, Israel., Perez M; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA., Thu CT; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA., Nance SR; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA., Amin R; Laboratory of Cancer Biology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA., Miller CN; Genome Modification Core, Laboratory Animal Sciences Program, Frederick National Laboratory for Cancer Research (FNLCR), Frederick, MD, USA., Holewinski RJ; Protein Mass Spectrometry Group, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA., Meyer T; CCR Collaborative Bioinformatics Resource (CCBR), Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc, Frederick, MD, USA., Koparde V; CCR Collaborative Bioinformatics Resource (CCBR), Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc, Frederick, MD, USA., Yang A; RNA Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA., Jailwala P; CCR Collaborative Bioinformatics Resource (CCBR), Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc, Frederick, MD, USA., Nguyen JT; Laboratory of Cancer Biology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA., Andresson T; Protein Mass Spectrometry Group, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA., Hunter K; Laboratory of Cancer Biology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA., Gu S; RNA Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA., Mock BA; Laboratory of Cancer Biology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA., Edmondson EF; Molecular Histopathology Laboratory, Laboratory Animal Sciences Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Difilippantonio S; Animal Research Technical Support, Laboratory Animal Sciences Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Chari R; Genome Modification Core, Laboratory Animal Sciences Program, Frederick National Laboratory for Cancer Research (FNLCR), Frederick, MD, USA., Schwartz S; Department of Molecular Genetics, Weizmann Institute of Science Rehovot 76100, Israel., O'Connell MR; Department of Biochemistry and Biophysics, Center for RNA Biology, School of Medicine and Dentistry, University of Rochester, Rochester, NY, USA., Chih-Chien Wu C; RNA Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA., Meier JL; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jul 28. Date of Electronic Publication: 2024 Jul 28.

Comparative analysis of drug-like EP300/CREBBP acetyltransferase inhibitors.

Autor: Crawford MC; Chemical Biology Laboratory, National Cancer Institute, Frederick, MD, USA., Tripu DR; Chemical Biology Laboratory, National Cancer Institute, Frederick, MD, USA., Barritt SA; Department of Pathology, Cancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., Jing Y; Chemical Biology Laboratory, National Cancer Institute, Frederick, MD, USA., Gallimore D; Chemical Biology Laboratory, National Cancer Institute, Frederick, MD, USA., Kales SC; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA., Bhanu NV; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, USA., Xiong Y; Chemical Biology Laboratory, National Cancer Institute, Frederick, MD, USA., Fang Y; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA., Butler KAT; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA., LeClair CA; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA., Coussens NP; Molecular Pharmacology Laboratories, Applied and Developmental Research Directorate, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Simeonov A; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA., Garcia BA; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, USA., Dibble CC; Department of Pathology, Cancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., Meier JL; Department of Pathology, Cancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 May 16. Date of Electronic Publication: 2023 May 16.