Acute dilation to alpha(2)-adrenoceptor antagonists uncovers dual constriction and dilation mediated by arterial alpha(2)-adrenoceptors.

Autor: Crassous, PA¹, Flavahan, S¹, Flavahan, NA¹, Crassous, P A² (AUTHOR), Flavahan, N A (AUTHOR)

Publikováno v: British Journal of Pharmacology. Nov2009, Vol. 158 Issue 5, p1344-1355. 12p.

The structural basis for an on-off switch controlling Gβγ-mediated inhibition of TRPM3 channels.

Autor: Behrendt M; Institut für Physiologie und Pathophysiologie, Philipps-Universität Marburg, 35037 Marburg, Germany.; Center for Mind, Brain and Behavior (CMBB), Philipps-Universität Marburg and Justus-Liebig-Universität Giessen, 35032 Marburg, Germany., Gruss F; Laboratory of Structural Neurobiology, Department of Cellular and Molecular Medicine, KU Leuven, 3000 Leuven, Belgium., Enzeroth R; Institut für Physiologie und Pathophysiologie, Philipps-Universität Marburg, 35037 Marburg, Germany.; Center for Mind, Brain and Behavior (CMBB), Philipps-Universität Marburg and Justus-Liebig-Universität Giessen, 35032 Marburg, Germany., Dembla S; Institut für Physiologie und Pathophysiologie, Philipps-Universität Marburg, 35037 Marburg, Germany.; Center for Mind, Brain and Behavior (CMBB), Philipps-Universität Marburg and Justus-Liebig-Universität Giessen, 35032 Marburg, Germany., Zhao S; Department of Pharmacology, Physiology and Neuroscience, Rutgers New Jersey Medical School, Newark, NJ 07103., Crassous PA; Department of Pharmacology, Physiology and Neuroscience, Rutgers New Jersey Medical School, Newark, NJ 07103., Mohr F; Institut für Physiologie und Pathophysiologie, Philipps-Universität Marburg, 35037 Marburg, Germany., Nys M; Laboratory of Structural Neurobiology, Department of Cellular and Molecular Medicine, KU Leuven, 3000 Leuven, Belgium., Louros N; Switch Laboratory, VIB Center for Brain and Disease Research, Department of Cellular and Molecular Medicine, KU Leuven, 3000 Leuven, Belgium., Gallardo R; Switch Laboratory, VIB Center for Brain and Disease Research, Department of Cellular and Molecular Medicine, KU Leuven, 3000 Leuven, Belgium., Zorzini V; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute for Medical Research, KU Leuven, 3000 Leuven, Belgium., Wagner D; Institut für Physiologie und Pathophysiologie, Philipps-Universität Marburg, 35037 Marburg, Germany., Economou A; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute for Medical Research, KU Leuven, 3000 Leuven, Belgium., Rousseau F; Switch Laboratory, VIB Center for Brain and Disease Research, Department of Cellular and Molecular Medicine, KU Leuven, 3000 Leuven, Belgium., Schymkowitz J; Switch Laboratory, VIB Center for Brain and Disease Research, Department of Cellular and Molecular Medicine, KU Leuven, 3000 Leuven, Belgium., Philipp SE; Experimentelle und Klinische Pharmakologie und Toxikologie, Universität des Saarlandes, 66421 Homburg, Germany., Rohacs T; Department of Pharmacology, Physiology and Neuroscience, Rutgers New Jersey Medical School, Newark, NJ 07103., Ulens C; Laboratory of Structural Neurobiology, Department of Cellular and Molecular Medicine, KU Leuven, 3000 Leuven, Belgium; chris.ulens@kuleuven.be johannes.oberwinkler@uni-marburg.de., Oberwinkler J; Institut für Physiologie und Pathophysiologie, Philipps-Universität Marburg, 35037 Marburg, Germany; chris.ulens@kuleuven.be johannes.oberwinkler@uni-marburg.de.; Center for Mind, Brain and Behavior (CMBB), Philipps-Universität Marburg and Justus-Liebig-Universität Giessen, 35032 Marburg, Germany.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Nov 17; Vol. 117 (46), pp. 29090-29100. Date of Electronic Publication: 2020 Oct 29.

The polymorphic deleted-form of the human α 2B -adrenergic receptor and its wild-type counterpart display post-receptor signaling pathway differences in LLC-PK1 cells.

Autor: Mastrogianni O; Department of Pharmacology, School of Medicine, University of Patras, 26504 Rio Patras, Greece., Crassous PA; INSERM Unit 388, Institut Louis Bugnard, IFR31, CHU Rangueil, 31400 Toulouse, France., Karkoulias G; Department of Pharmacology, School of Medicine, University of Patras, 26504 Rio Patras, Greece., Lykouras D; Department of Pharmacology, School of Medicine, University of Patras, 26504 Rio Patras, Greece., Schaak S; INSERM Unit 388, Institut Louis Bugnard, IFR31, CHU Rangueil, 31400 Toulouse, France., Patsouras N; Department of Pharmacology, School of Medicine, University of Patras, 26504 Rio Patras, Greece., Panayiotakopoulos G; Department of Pharmacology, School of Medicine, University of Patras, 26504 Rio Patras, Greece., Sivolapenko G; Laboratory of Pharmacokinetics, Department of Pharmacy, University of Patras, Patras, Greece., Paris H; INSERM Unit 388, Institut Louis Bugnard, IFR31, CHU Rangueil, 31400 Toulouse, France., Manolis AS; Third Department of Cardiology, Athens University School of Medicine, Athens, Greece. Electronic address: asm@otenet.gr., Flordellis C; Department of Pharmacology, School of Medicine, University of Patras, 26504 Rio Patras, Greece. Electronic address: flordell@med.upatras.gr.

Publikováno v: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese [Hellenic J Cardiol] 2016 Aug 20. Date of Electronic Publication: 2016 Aug 20.

Protein disulfide-isomerase interacts with soluble guanylyl cyclase via a redox-based mechanism and modulates its activity.

Autor: Heckler EJ; Department of Pharmacology and Physiology, New Jersey Medical School, UMDNJ, Newark, NJ 07103, USA. heckleer@umdnj.edu, Crassous PA, Baskaran P, Beuve A

Publikováno v: The Biochemical journal [Biochem J] 2013 May 15; Vol. 452 (1), pp. 161-9.

Soluble guanylyl cyclase is a target of angiotensin II-induced nitrosative stress in a hypertensive rat model.

Autor: Crassous PA; Department of Pharmacology and Physiology, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey 07103, USA., Couloubaly S, Huang C, Zhou Z, Baskaran P, Kim DD, Papapetropoulos A, Fioramonti X, Durán WN, Beuve A

Publikováno v: American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2012 Sep 01; Vol. 303 (5), pp. H597-604. Date of Electronic Publication: 2012 Jun 22.