Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Cranfield, CG"'
Autor:
Wu, J, Yu, TT, Kuppusamy, R, Hassan, MM, Alghalayini, A, Cranfield, CG, Willcox, MDP, Black, DS, Kumar, N
There is a significant and urgent need for the development of novel antibacterial agents to tackle the increasing incidence of antibiotic resistance. Cholic acid-based small molecular antimicrobial peptide mimics are reported as potential new leads t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::70e05a29ece03caa2f4e42730e81981f
https://hdl.handle.net/10453/164342
https://hdl.handle.net/10453/164342
Statins are a class of drugs used to lower low-density lipoprotein cholesterol and are amongst the most prescribed medications worldwide. Most statins work as a competitive inhibitor of 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMGR), but sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::907ea6ee86bf0e3f5487d25ad445541f
https://hdl.handle.net/10453/144411
https://hdl.handle.net/10453/144411
Despite the central role of Na+ and K+ in physiological processes, it is still unclear whether they interact or alter the physical properties of simple zwitterionic phospholipid bilayers at physiologically relevant concentrations. Here we report a di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::e026d3f444e27efccc02c3253cd3d9f6
https://hdl.handle.net/10453/141926
https://hdl.handle.net/10453/141926
Plasmon resonance frequency irradiated gold nanoparticles (GNPs) have gained interest as a laser-targeted treatment for infections, tumors and for the controlled release of drugs in situ. Questions still remain, however, as to the efficiency of heat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::2a21139f579e7e78af7ebcd8d69cb1d0
https://hdl.handle.net/10453/145409
https://hdl.handle.net/10453/145409
Autor:
Martin AD, Wojciechowski JP, Du EY, Rawal A, Stefen H, Au CG, Hou L, Cranfield CG, Fath T, Ittner LM, Thordarson P
© The Royal Society of Chemistry. Peptide-based nanofibres are a versatile class of tunable materials with applications in optoelectronics, sensing and tissue engineering. However, the understanding of the nanofibre surface at the molecular level is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::76424f35d05dd429978067d2cd477606
https://hdl.handle.net/10453/142818
https://hdl.handle.net/10453/142818
Autor:
Yu, TT, Nizalapur, S, Ho, KKK, Yee, E, Berry, T, Cranfield, CG, Willcox, M, Black, DSC, Kumar, N
© 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim Antibiotic resistance is a major global health concern. There is an urgent need for the development of novel antimicrobials. Recently, phenylglyoxamide-based small molecular antimicrobial peptide mim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::eecf90516a1c85482ae23f033c30a1e5
https://hdl.handle.net/10453/124139
https://hdl.handle.net/10453/124139
Autor:
Cranfield, CG, Berry, T, Holt, SA, Hossain, KR, Le Brun, AP, Carne, S, Al Khamici, H, Coster, H, Valenzuela, SM, Cornell, B
© 2016 American Chemical Society. This study explains the importance of the phosphate moiety and H3O+ in controlling the ionic flux through phospholipid membranes. We show that despite an increase in the H3O+ concentration when the pH is decreased,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::66d977332dc29d210fbf9858d0e3a622
https://hdl.handle.net/10453/54908
https://hdl.handle.net/10453/54908
In this work, we present experimental data, supported by a quantitative model, on the generation and effect of potential gradients across a tethered bilayer lipid membrane (tBLM) with, to the best of our knowledge, novel architecture. A challenge to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::3f99e50beeb13d89537dd2b6f1e9a474
https://hdl.handle.net/10453/30150
https://hdl.handle.net/10453/30150