Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Crandell, Addington"'
Autor:
Peiying Yang, Lin Tan, Sun Jin Kim, Vikas Kundra, Ho Jeong Lee, Mihai Gagea, Yong Pan, Carrie Cartwright, Patrea Rhea, Murali Ravoori, Crandell Addington, Robert A. Newman
Publikováno v:
Investigational New Drugs
SummaryIntroduction Oleandrin, a cardiac glycoside, exerts strong anti-proliferative activity against various human malignancies in in vitro cells. Here, we report the antitumor efficacy of PBI-05204, a supercritical C02 extract of Nerium oleander co
Autor:
Ignacio I. Wistuba, Ekem Efuet, Imad Shureiqi, David G. Menter, Carrie Cartwright, Stanley R. Hamilton, Peiying Yang, Crandell Addington, Robert A. Newman
Publikováno v:
Molecular Carcinogenesis. 53:253-263
The purpose of this study was to investigate whether intracellular distribution of Na+, K+-ATPase α3 subunit, a receptor for cardiac glycosides including oleandrin, is differentially altered in cancer versus normal cells and whether this altered dis
Autor:
Robert A, Newman, Peiying, Yang, Walter N, Hittelman, Tao, Lu, Dah Hsi, Ho, Dan, Ni, Diana, Chan, Mary, Vijjeswarapu, Carrie, Cartwright, Susan, Dixon, Edward, Felix, Crandell, Addington
Publikováno v:
Journal of experimental therapeuticsoncology. 5(3)
While certain cardiac glycoside compounds such as oleandrin, bufalin and digitoxin are known to be associated with potent cytotoxicity to human tumor cells, the mechanisms by which this effect is produced are not clear. We now demonstrate that incuba
Autor:
Ho Jeong Lee, Crandell Addington, Robert A. Newman, Mihai Gagea, Sun Jin Kim, Yong Pan, Carrie Cartwright, Patrea Rhea, Peiying Yang
Publikováno v:
Cancer Research. 73:5554-5554
Recent studies have suggested that cardiac glycosides (CGs), such as oleandrin, have an ability to inhibit the proliferation of various cancer cells, including those from pancreatic, non-small cell lung cancer, prostate, colon and breast cancers. How