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Autor:
Craik, Vivian Cody, Jia Q. Truong, Bruce A. Holdsworth, Jessica K. Holien, Samantha J. Richardson, David K. Chalmers, David J.
Publikováno v:
Molecules; Volume 27; Issue 21; Pages: 7206
Human transthyretin (hTTR) can form amyloid deposits that accumulate in nerves and organs, disrupting cellular function. Molecules such as tafamidis that bind to and stabilize the TTR tetramer can reduce such amyloid formation. Here, we studied the i