Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Craige C, Wrenn"'
Autor:
Mark P. Reilly, Craige C. Wrenn, Maria G. Valdovinos, Ryan Kirk, E J French, Randall McCallian, Dustin F. Baker
Publikováno v:
Psychopharmacology. 238:1133-1140
Fragile X syndrome (FXS), the most prevalent genetic form of intellectual disability, is characterized by intellectual impairment, impaired sociability, aggression, self-injury, hyperactivity, and attention deficits. A consequence of the hyperactivit
Autor:
Craige C, Wrenn, Eric, French, Dustin, Baker, Randall, McCallian, Ryan, Kirk, Mark P, Reilly, Maria G, Valdovinos
Publikováno v:
Psychopharmacology. 238(4)
Fragile X syndrome (FXS), the most prevalent genetic form of intellectual disability, is characterized by intellectual impairment, impaired sociability, aggression, self-injury, hyperactivity, and attention deficits. A consequence of the hyperactivit
Publikováno v:
Alzheimer's & Dementia. 14
Publikováno v:
Alzheimer's & Dementia. 14
Publikováno v:
Neuroscience Letters. 585:109-113
Fragile X syndrome (FXS), a disorder caused by a mutation in the FMR1 gene, is often associated with Attention Deficit Hyperactivity Disorder (ADHD). Common treatments for the hyperactivity often seen in ADHD involve the use of stimulants and α2-adr
Publikováno v:
Journal of Autism and Developmental Disorders. 43:1452-1458
Social behavior abnormalities in Fragile X syndrome (FXS) are characterized by social withdrawal, anxiety, and deficits in social cognition. To assess these deficits, a model of FXS, the Fmr1 knockout mouse (Fmr1 KO), has been utilized. This mouse mo
Autor:
Craige C. Wrenn, Jacqueline N. Crawley, Sophie Schlosser, Jennifer L. Dreiling, Janita Turchi, Dejaimenay Stephenson
Publikováno v:
Pharmacology Biochemistry and Behavior. 83:428-440
The neuropeptide galanin impairs learning and memory in rodents. The mechanism underlying the cognitive effects of galanin may be related to inhibitory effects of galanin on cholinergic transmission. As cholinergic function is thought to modulate sus
Autor:
Rebecca J. Yang, Timothy L. Sullivan, Jacqueline N. Crawley, Katharine C. Long, Nathan R. Rustay, Caitlin E. Innerfield, Kathleen R. Bailey, Jefferson W. Kinney, Maria C. Saavedra, Andrew Holmes, Grzegorz Starosta, Craige C. Wrenn, Ashley P. Harris, Jennifer L. Dreiling
Publikováno v:
Neuropeptides. 39:239-243
Galanin (GAL) impairs performance on cognitive tasks when administered centrally to rats. GAL transgenic (GAL-tg) mice overexpressing endogenous GAL show deficits on the probe trial of the Morris water maze spatial learning task, on the social transm
Autor:
Craige C. Wrenn, John Shine, Rebecca J. Yang, Jefferson W. Kinney, Li Ma, Andrew Holmes, Jacqueline N. Crawley, Janani Vishwanath, Qian Li, Arie S. Jacoby, Tiina P. Iismaa, Caitlin E. Innerfield, Maria C. Saavedra
Publikováno v:
Neuropsychopharmacology. 28:1031-1044
The neuropeptide galanin coexists with norepinephrine and serotonin in neural systems mediating emotion. Previous findings suggested that galanin modulates anxiety-related behaviors in rodents. Three galanin receptor subtypes have been cloned; howeve
Autor:
Gary L. Wenk, Jefferson W. Kinney, Andrew Holmes, Craige C. Wrenn, Lisa K. Marriott, Jacqueline N. Crawley
Publikováno v:
Neuropeptides. 36:413-426
Galanin-overexpressing transgenic mice (GAL-tg) generated on a dopamine beta-hydroxylase promoter were previously shown to express high levels of galanin mRNA in the locus coeruleus, and to perform poorly on challenging cognitive tasks. The present s