Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Craig Wilkinson"'
Autor:
Kun-Mou Li, Craig Wilkinson, Juho Kellosalo, Jia-Yin Tsai, Tommi Kajander, Lars J. C. Jeuken, Yuh-Ju Sun, Adrian Goldman
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
In some parasites, membrane-bound pyrophosphatases, which couple proton and sodium ion transport across the membrane, are important for infectivity. Here, the authors report crystal structures of these proteins alongside biophysical analyses that all
Externí odkaz:
https://doaj.org/article/9bf03144000f411fad9765f84873b5f9
Autor:
Nita R. Shah, Craig Wilkinson, Steven P. D. Harborne, Ainoleena Turku, Kun-Mou Li, Yuh-Ju Sun, Sarah Harris, Adrian Goldman
Publikováno v:
Structural Dynamics, Vol 4, Iss 3, Pp 032105-032105-12 (2017)
Membrane-integral pyrophosphatases (mPPases) couple the hydrolysis of pyrophosphate (PPi) to the pumping of Na+, H+, or both these ions across a membrane. Recently solved structures of the Na+-pumping Thermotoga maritima mPPase (TmPPase) and H+-pumpi
Externí odkaz:
https://doaj.org/article/317fe7dc8b6547d3aeee4f1e62d4d008
Publikováno v:
SAE Technical Paper Series.
Anti-lock brake systems (ABS) produce high levels of vehicle deceleration under emergency braking conditions by modulating tire slip. Currently there are limited data available to quantify the mean, variance, and distribution of vehicle deceleration
Autor:
Jannik Strauss, Craig Wilkinson, Keni Vidilaseris, Orquidea Ribeiro, Jianing Liu, James Hillier, Anssi Malinen, Bernadette Gehl, Lars J.C. Jeuken, Arwen R. Pearson, Adrian Goldman
Membrane-bound pyrophosphatases (M-PPases) are homodimeric primary ion pumps that couple the transport of Na+- and/or H+across membranes to the hydrolysis of pyrophosphate. Their role in the virulence of protist pathogens likePlasmodium falciparummak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9efa3c66a8e72459e22659b204477a74
https://doi.org/10.1101/2022.11.07.515396
https://doi.org/10.1101/2022.11.07.515396
Publikováno v:
Methods in enzymology. 607
Membrane-bound pyrophosphatases (mPPases) couple pyrophosphate hydrolysis to H
Autor:
Yuh-Ju Sun, Adrian Goldman, Steven P. D. Harborne, Nita R. Shah, Craig Wilkinson, Ainoleena Turku, Kun-Mou Li, Sarah A. Harris
Publikováno v:
Structural Dynamics
Structural Dynamics, Vol 4, Iss 3, Pp 032105-032105-12 (2017)
Structural Dynamics, Vol 4, Iss 3, Pp 032105-032105-12 (2017)
Membrane-integral pyrophosphatases (mPPases) couple the hydrolysis of pyrophosphate (PPi) to the pumping of Na+, H+, or both these ions across a membrane. Recently solved structures of the Na+-pumping Thermotoga maritima mPPase (TmPPase) and H+-pumpi
Autor:
Martin J. McPhillie, David W. Rice, Craig W. Roberts, Rima McLeod, Colin W. G. Fishwick, Craig Wilkinson, Gustavo A. Afanador, Ying Zhou, Sean T. Prigge, Shaun Rawson, Farzana Khaliq, Stephen P. Muench, Stuart Woods
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24(3):911-916
The enoyl acyl-carrier protein reductase (ENR) enzyme of the apicomplexan parasite family has been intensely studied for antiparasitic drug design for over a decade, with the most potent inhibitors targeting the NAD+ bound form of the enzyme. However
Autor:
Sarah A. Harris, Roman Tuma, Adrian Goldman, Steven P. D. Harborne, Christos Pliotas, Craig Wilkinson, Nita R. Shah
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 74:e33-e33
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 73:a310-a310
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 71:s23-s24