Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Craig Walsh"'
Autor:
Jessica Ramirez Sanchez, Samual Marsh, Laura McIntyre, Hayk Davtyan, Craig Walsh, Mathew Blurton-Jones
Publikováno v:
The Journal of Immunology. 204:64.4-64.4
The role of the adaptive immune system, specifically T cells, remains poorly understood in Alzheimer’s disease (AD) pathogenesis research. Our lab generated an immune-deficient mouse model of AD (RAG2ɣc−/−5xfAD) which showed a dramatic increas
Autor:
Hamad Alshetaiwi, Nicholas Pervolarakis, Laura L. McIntyre, Dennis Ma, Quy Nguyen, Kevin Nee, Jan Rath, Katrina Evans, Leona Torosian, Anushka Silva, Craig Walsh, Kai Kessenbrock
Publikováno v:
The Journal of Immunology. 202:135.4-135.4
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid cells with potent immune suppressive activity. MDSCs regulate anti-tumor immunity by suppressing T cell proliferation. MDSCs can be further classified into gr
Autor:
Craig Walsh, Robert W. Hodson, Eric Kirker, Ethan C Korngold, Sarah Leanne Ramelli, Jeffrey S. Swanson
Publikováno v:
Circulation. Cardiovascular interventions. 9(10)
Transcatheter aortic valve replacement (TAVR) is an approved and widely accepted standard treatment for severe symptomatic aortic stenosis (AS) in high-risk surgical candidates.1 Severe symptomatic AS during pregnancy presents a difficult clinical ch
Autor:
Martina Gatzka, Craig Walsh
Publikováno v:
Current Immunology Reviews. 4:190-198
Publikováno v:
Scopus-Elsevier
Tumor cells insensitive to lysis through the Fas and TNF pathways were injected either subcutaneously or into the peritoneal cavities of allogeneic perforin-less (P0) and perforin wild-type (P2) mice. In three of four cases, the tumors were rejected
Autor:
Craig Walsh
Publikováno v:
AfCS-Nature Molecule Pages.
The last lecture on leadership by the NFL's greatest coach: Bill Walsh Bill Walsh is a towering figure in the history of the NFL. His advanced leadership transformed the San Francisco 49ers from the worst franchise in sports to a legendary dynasty. I
Publikováno v:
The Journal of Immunology. 190:185.5-185.5
Complement protein C1q opsonizes apoptotic cells (AC) to enhance ingestion by human monocyte-derived macrophages (Mϕ) before membrane integrity of the dying cell is lost, thus avoiding the release of inflammatory DAMPS and/or autoantigens. Additiona
Publikováno v:
The Journal of Immunology. 188:126.24-126.24
Drak2 is a serine threonine kinase that has previously been shown to negatively regulate activation of T cells through the T cell receptor. Here we demonstrate that loss of DRAK2 signaling significantly promotes the acceptance of allogeneic engraftme
Autor:
Jennifer Lu, Brian Weist, Bram van Raam, Brett Marro, Long Nguyen, Prathna Srinivas, Bryan Bell, Luhrs Keith, Thomas Lane, Guy Salvesen, Craig Walsh
Publikováno v:
The Journal of Immunology. 188:163.24-163.24
T cells lacking caspase 8 develop a hyper-autophagic morphology, and succumb to a programmed necrosis-like death process termed necroptosis. RIP kinases RIPK1 and RIPK3 together facilitate necroptosis in response to TNF-α ligation and mitogenic stim