Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Craig W. Vander Kooi"'
Autor:
Ying Wang, Enfeng Wang, Mohamed Anany, Simone Füllsack, Yu Henry Huo, Shamit Dutta, Baoan Ji, Luke H. Hoeppner, Sreenivasulu Kilari, Sanjay Misra, Thomas Caulfield, Craig W. Vander Kooi, Harald Wajant, Debabrata Mukhopadhyay
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Tumor necrosis factor-α (TNFα) is a master cytokine which induces expression of chemokines and adhesion molecules, such as intercellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion molecule 1 (VCAM-1), in endothelial cells to initiate t
Externí odkaz:
https://doaj.org/article/d7a930a7344841bea90dc907c25388c8
Autor:
Federica Pondrelli, Raffaella Minardi, Lorenzo Muccioli, Corrado Zenesini, Luca Vignatelli, Laura Licchetta, Barbara Mostacci, Paolo Tinuper, Craig W. Vander Kooi, Matthew S. Gentry, Francesca Bisulli
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-10 (2023)
Abstract Background Lafora disease (LD) is a fatal form of progressive myoclonic epilepsy caused by biallelic pathogenic variants in EPM2A or NHLRC1. With a few exceptions, the influence of genetic factors on disease progression has yet to be confirm
Externí odkaz:
https://doaj.org/article/a141b74afcff49a9a4cd0c5090e3921e
Autor:
M. Kathryn Brewer, Maria Machio-Castello, Rosa Viana, Jeremiah L. Wayne, Andrea Kuchtová, Zoe R. Simmons, Sarah Sternbach, Sheng Li, Maria Adelaida García-Gimeno, Jose M. Serratosa, Pascual Sanz, Craig W. Vander Kooi, Matthew S. Gentry
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103276- (2021)
Summary: Lafora disease (LD) is a fatal childhood dementia characterized by progressive myoclonic epilepsy manifesting in the teenage years, rapid neurological decline, and death typically within ten years of onset. Mutations in either EPM2A, encodin
Externí odkaz:
https://doaj.org/article/08a505503d644df58c43dc58bd8a2937
Autor:
Xiuping Huang, Qing Ye, Min Chen, Aimin Li, Wenting Mi, Yuxin Fang, Yekaterina Y. Zaytseva, Kathleen L. O’Connor, Craig W. Vander Kooi, Side Liu, Qing-Bai She
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
O-glycosylation of neuropilin-1 is involved in cancer migration and invasion. Here, the authors show that defects in N-glycosylation of two neuropilin-1 splice variants enhance the co-internalisation of Met, it’s interaction with β1-integrin, and
Externí odkaz:
https://doaj.org/article/f6010641cbee4136a32b4af22c39248b
Autor:
Hira Lal Goel, Bryan Pursell, Leonard D. Shultz, Dale L. Greiner, Rolf A. Brekken, Craig W. Vander Kooi, Arthur M. Mercurio
Publikováno v:
Cell Reports, Vol 14, Iss 9, Pp 2193-2208 (2016)
Autocrine VEGF signaling is critical for sustaining prostate and other cancer stem cells (CSCs), and it is a potential therapeutic target, but we observed that CSCs isolated from prostate tumors are resistant to anti-VEGF (bevacizumab) and anti-VEGFR
Externí odkaz:
https://doaj.org/article/8c17537e827f446195f5c1b49e43bb2d
Autor:
Nathan A. McDonald, Yoshimasa Takizawa, Anna Feoktistova, Ping Xu, Melanie D. Ohi, Craig W. Vander Kooi, Kathleen L. Gould
Publikováno v:
Cell Reports, Vol 14, Iss 3, Pp 534-546 (2016)
F-BAR proteins link cellular membranes to the actin cytoskeleton in many biological processes. Here we investigated the function of the Schizosaccharomyces pombe Imp2 F-BAR domain in cytokinesis and find that it is critical for Imp2’s role in contr
Externí odkaz:
https://doaj.org/article/48b27fc373d44fd284298e25045681a1
Autor:
Naofumi Amioka, Chia-Hua Wu, Hisashi Sawada, Sohei Ito, Alex C. Pettey, Congqing Wu, Jessica J. Moorleghen, Deborah A. Howatt, Gregory A. Graf, Craig W. Vander Kooi, Alan Daugherty, Hong S. Lu
BackgroundAngiotensinogen (AGT) is an essential component in the renin-angiotensin system. AGT has highly conserved sequences in the loop and β-sheet regions among species; however, their functions have not been studied.MethodsAdeno-associated viral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdb94ac582e23ccc24cfa2fdcf072c1b
https://doi.org/10.1101/2022.12.22.521618
https://doi.org/10.1101/2022.12.22.521618
Autor:
Amanda L. Photenhauer, Filipe M. Cerqueira, Rosendo Villafuerte-Vega, Krista M. Armbruster, Filip Mareček, Tiantian Chen, Zdzislaw Wawrzak, Jesse B. Hopkins, Craig W. Vander Kooi, Štefan Janeček, Brandon T. Ruotolo, Nicole M. Koropatkin
Resistant starch is a prebiotic with breakdown by gut bacteria requiring the action of specialized amylases and starch-binding proteins. The human gut symbiontRuminococcus bromiiexpresses granular starch-binding protein Sas6 (Starch Adherence System
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffefc67d77ebb93ba4c31d31967c74bb
https://doi.org/10.1101/2022.11.20.514607
https://doi.org/10.1101/2022.11.20.514607
Autor:
Lyndsay E A Young, Lindsey R Conroy, Harrison A Clarke, Tara R Hawkinson, Kayli E Bolton, William C Sanders, Josephine E Chang, Madison B Webb, Warren J Alilain, Craig W Vander Kooi, Richard R Drake, Douglas A Andres, Tom C Badgett, Lars M Wagner, Derek B Allison, Ramon C Sun, Matthew S Gentry
Publikováno v:
EMBO Molecular Medicine. 14
Glycogen dysregulation is a hallmark of aging, and aberrant glycogen drives metabolic reprogramming and pathogenesis in multiple diseases. However, glycogen heterogeneity in healthy and diseased tissues remains largely unknown. Herein, we describe a
Publikováno v:
The FASEB Journal. 36