Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Craig Underhill"'
Autor:
Sarah Glewis, Mei Krishnasamy, Senthil Lingaratnam, Sam Harris, Craig Underhill, Chloe Georgiou, Mark Warren, Robert Campbell, Maarten IJzerman, Mussab Fagery, Ian Campbell, Jennifer H. Martin, Jeanne Tie, Marliese Alexander, Michael Michael
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 12, Pp 2700-2708 (2023)
Abstract This study explored the acceptability of a novel pharmacist‐led pharmacogenetics (PGx) screening program among patients with cancer and healthcare professionals (HCPs) taking part in a multicenter clinical trial of PGx testing (PACIFIC‐P
Externí odkaz:
https://doaj.org/article/4034bb7ba4d84e32bda0fff26aa22e13
Autor:
Wenjing Wang, Yu Xia, Charlotte Lemech, Adnan Nagrial, Baiyong Li, Zhongmin Maxwell Wang, Sophia Frentzas, Anna Rachelle Austria Mislang, Craig Underhill, Jermaine I G Coward
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background Studies showed that vascular endothelial growth factor (VEGF) inhibitors could improve therapeutic efficacy of PD-1/PD-L1 antibodies by transforming the immunosuppressive tumor microenvironment (TME) into an immunoresponsive TME. Ivonescim
Externí odkaz:
https://doaj.org/article/94eb2c1d24274681b9ae9f7010b69141
Autor:
Ciara Conduit, Blossom Mak, Wenjia Qu, Juliana Di Lulio, Ronan Burder, Matthias Bressel, Thomas Cusick, Haryana M. Dhillon, Richard De Abreu Lourenço, Craig Underhill, Javier Torres, Megan Crumbaker, Florian Honeyball, Anthony Linton, Ray Allen, Ian D. Davis, Susan J. Clark, Lisa G. Horvath, Kate L. Mahon
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Objective: To determine the efficacy and safety of intermittent docetaxel chemotherapy guided by circulating methylated glutathione S-transferase Pi-1 ( mGSTP1 ) in men with metastatic castration-resistant prostate cancer (CRPC). Patients and Methods
Externí odkaz:
https://doaj.org/article/a39320096f8748238086520bc5368c74
Autor:
Nathan Bain, Mike Nguyen, Lisa Grech, Daphne Day, Amelia McCartney, Kate Webber, Alastair Kwok, Sam Harris, Hieu Chau, Bryan Chan, Louise Nott, Nada Hamad, Annette Tognela, Craig Underhill, Bao Sheng Loe, Daniel Freeman, Eva Segelov, on behalf of the CANVACCS Investigators
Publikováno v:
Vaccines, Vol 10, Iss 9, p 1373 (2022)
Background: Vaccination is the cornerstone of the global public health response to the COVID-19 pandemic. Excess morbidity and mortality of COVID-19 infection is seen in people with cancer. COVID-19 vaccine hesitancy has been observed in this medical
Externí odkaz:
https://doaj.org/article/3ecd05934bfc454a9d051dc021580b30
Autor:
Jeanne Tie, Yuxuan Wang, Joshua Cohen, Lu Li, Wei Hong, Michael Christie, Hui Li Wong, Suzanne Kosmider, Rachel Wong, Benjamin Thomson, Julian Choi, Adrian Fox, Kathryn Field, Matthew Burge, Jenny Shannon, Dusan Kotasek, Niall C Tebbutt, Christos Karapetis, Craig Underhill, Andrew Haydon, Joy Schaeffer, Janine Ptak, Cristian Tomasetti, Nicholas Papadopoulos, Kenneth W Kinzler, Bert Vogelstein, Peter Gibbs
Publikováno v:
PLoS Medicine, Vol 18, Iss 5, p e1003620 (2021)
BackgroundIn patients with resectable colorectal liver metastases (CRLM), the role of pre- and postoperative systemic therapy continues to be debated. Previous studies have shown that circulating tumor DNA (ctDNA) analysis, as a marker of minimal res
Externí odkaz:
https://doaj.org/article/5fefae544f494349b57c0bd567ac52e2
Autor:
Daphne Day, Lisa Grech, Mike Nguyen, Nathan Bain, Alastair Kwok, Sam Harris, Hieu Chau, Bryan Chan, Richard Blennerhassett, Louise Nott, Nada Hamad, Annette Tognela, David Hoffman, Amelia McCartney, Kate Webber, Jennifer Wong, Craig Underhill, Brett Sillars, Antony Winkel, Mark Savage, Bao Sheng Loe, Daniel Freeman, Eva Segelov, on behalf of the CANVACCS, DIABVACCS and MSVACCS Investigators
Publikováno v:
Vaccines, Vol 10, Iss 6, p 851 (2022)
As COVID-19 vaccinations became available and were proven effective in preventing serious infection, uptake amongst individuals varied, including in medically vulnerable populations. This cross-sectional multi-site study examined vaccine uptake, hesi
Externí odkaz:
https://doaj.org/article/d55efc600f1647f7837aaf47093bbd8f
Autor:
Christopher J Sweeney, Andrew J Martin, Martin R Stockler, Stephen Begbie, Leanna Cheung, Kim N Chi, Simon Chowdhury, Mark Frydenberg, Lisa G Horvath, Anthony M Joshua, Nicola J Lawrence, Gavin Marx, John McCaffrey, Ray McDermott, Margaret McJannett, Scott A North, Francis Parnis, Wendy Parulekar, David W Pook, Martin Neil Reaume, Shahneen K Sandhu, Alvin Tan, Thean Hsiang Tan, Alastair Thomson, Francisco Vera-Badillo, Scott G Williams, Diana Winter, Sonia Yip, Alison Y Zhang, Robert R Zielinski, Ian D Davis, Ehtesham Abdi, Suzanne Allan, Patricia Bastick, Robert Blum, Karen Briscoe, Daniel Brungs, Sean Bydder, Bala Renuka Chittajallu, Michelle Cronk, Katharine Cuff, Anthony Dowling, Matthew George, Lisa Horvath, Elizabeth Hovey, Anthony Joshua, Narayan Karanth, Ganessan Kichenadasse, Laurence Krieger, Maitham Mathlum, Louise Nott, Zulfiquer Otty, David Pook, Shahneen Sandhu, Sanjeev Sewak, Amanda Stevanovic, Martin Stockler, Aneta Suder, Hsiang Tan, Javier Torres, Simon Troon, Craig Underhill, Andrew Weickhardt, Robert Zielinski, Tahir Abbas, Ghadeer Anan, Chris Booth, Holly Campbell, Kim Chi, Joseph Chin, Edmond Chouinard, Bryan Donnelly, Darrel Drachenberg, Amir Faghih, Antonio Finelli, Sebastien Hotte, Krista Noonan, Scott North, Mohammad Rassouli, Neil Reaume, Ricardo Rendon, Fred Saad, Evgeny Sadikov, Eric Vigneault, Pawel Zalewski, Patrick Morris, Miriam O'Connor, Paul Donnellan, Dearbhaile O'Donnell, Jim Edwards, Peter Fong, Simon Crabb, Omar Khan, Vincent Khoo, Graham Macdonald, Heather Payne, Angus Robinson, Jonathon Shamash, John Staffurth, Carys Thomas
Publikováno v:
The Lancet Oncology. 24:323-334
Autor:
Sarah Glewis, Marliese Alexander, Senthil Lingaratnam, Benjamin Lee, Ian Campbell, Mei Krishnasamy, Maarten IJzerman, Mussab Fagery, Sam Harris, Chloe Georgiou, Craig Underhill, Mark Warren, Robert Campbell, Jennifer Martin, Jeanne Tie, Michael Michael
Publikováno v:
Acta Oncologica. 61:1136-1139
Pharmacogenomics guided dosing for fluoropyrimidine and irinotecan chemotherapies for patients with cancer (PACIFIC-PGx): study protocol of a multicentre clinical trial
Autor:
Jonathan Cebon, Jodie Palmer, Jane Y. So, Andreas Behren, Adnan Nagrial, Clare Scott, Caroline Lum, Louise Jackett, Matteo S. Carlino, Craig Underhill, Michael Michael, Ben Markman, Damien Kee, Oliver Klein
Best response according to histological grade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45912f4ae01d660cae9a65228c3df402
https://doi.org/10.1158/1078-0432.22476674.v1
https://doi.org/10.1158/1078-0432.22476674.v1
Autor:
Jonathan Cebon, Jodie Palmer, Jane Y. So, Andreas Behren, Adnan Nagrial, Clare Scott, Caroline Lum, Louise Jackett, Matteo S. Carlino, Craig Underhill, Michael Michael, Ben Markman, Damien Kee, Oliver Klein
Purpose:Combination immunotherapy with anti–CTLA-4 and anti–PD-1 blockade has demonstrated significant clinical activity across several tumor types. Neuroendocrine tumors (NET) are a heterogeneous group of rare tumors with limited treatment optio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19988cc357311f4937dec57048f4e9c5
https://doi.org/10.1158/1078-0432.c.6529460.v1
https://doi.org/10.1158/1078-0432.c.6529460.v1