Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Craig S. Nowell"'
Autor:
Kathy E O'Neill, Nicholas Bredenkamp, Christin Tischner, Harsh J Vaidya, Frances H Stenhouse, C Diana Peddie, Craig S Nowell, Terri Gaskell, C Clare Blackburn
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151666 (2016)
Thymus function requires extensive cross-talk between developing T-cells and the thymic epithelium, which consists of cortical and medullary TEC. The transcription factor FOXN1 is the master regulator of TEC differentiation and function, and declinin
Externí odkaz:
https://doaj.org/article/16c761d49bd44448a38f17c9ffa3a358
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114842 (2014)
Normal thymus function reflects interactions between developing T-cells and several thymic stroma cell types. Within the stroma, key functions reside in the distinct cortical and medullary thymic epithelial cell (TEC) types. It has been demonstrated
Externí odkaz:
https://doaj.org/article/64ff6000489f4cf9b1313ddfd4734f7c
Autor:
Craig S Nowell, Nicholas Bredenkamp, Stéphanie Tetélin, Xin Jin, Christin Tischner, Harsh Vaidya, Julie M Sheridan, Frances Hogg Stenhouse, Raphaela Heussen, Andrew J H Smith, C Clare Blackburn
Publikováno v:
PLoS Genetics, Vol 7, Iss 11, p e1002348 (2011)
The forkhead transcription factor Foxn1 is indispensable for thymus development, but the mechanisms by which it mediates thymic epithelial cell (TEC) development are poorly understood. To examine the cellular and molecular basis of Foxn1 function, we
Externí odkaz:
https://doaj.org/article/4f25ee44dc6b4291a990152910e524ce
Autor:
Freddy Radtke, Craig S. Nowell
Publikováno v:
Nature Reviews Cancer. 17:145-159
The Notch signalling cascade is an evolutionarily conserved pathway that has a crucial role in regulating development and homeostasis in various tissues. The cellular processes and events that it controls are diverse, and continued investigation over
Autor:
Freddy Radtke, Craig S. Nowell
Publikováno v:
Notch Signaling ISBN: 9789811049705
Aberrant Notch signalling is associated with a variety of solid tumours. Therefore, understanding the role Notch signalling plays during the development and progression of cancer is an area of considerable interest, and a deeper knowledge of its infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bd803c46b8426345e530658a4d5497d
https://doi.org/10.1007/978-981-10-4971-2_6
https://doi.org/10.1007/978-981-10-4971-2_6
Autor:
Bhushan Sarode, Alexandre Moulin, Craig S. Nowell, Yvan Arsenijevic, JongEun Ihm, Friedrich Beermann, Freddy Radtke, Daniel F. Schorderet, Corinne Kostic
Publikováno v:
Pigment Cell & Melanoma Research. 27:580-589
The ciliary body and iris are pigmented epithelial structures in the anterior eye segment that function to maintain correct intra-ocular pressure and regulate exposure of the internal eye structures to light, respectively. The cellular and molecular
Autor:
C. Diana Peddie, C. Clare Blackburn, Craig S. Nowell, Christin Tischner, Nicholas Bredenkamp, Frances H. Stenhouse, Terri Gaskell, Kathy E. O'Neill, Harsh J. Vaidya
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151666 (2016)
PLoS ONE
O'Neill, K E, Bredenkamp, N, Tischner, C, Vaidya, H J, Stenhouse, F H, Peddie, C D, Nowell, C S, Gaskell, T & Blackburn, C C 2016, ' Foxn1 Is Dynamically Regulated in Thymic Epithelial Cells during Embryogenesis and at the Onset of Thymic Involution ', PLoS ONE, vol. 11, no. 3, pp. e0151666 . https://doi.org/10.1371/journal.pone.0151666
PLoS ONE
O'Neill, K E, Bredenkamp, N, Tischner, C, Vaidya, H J, Stenhouse, F H, Peddie, C D, Nowell, C S, Gaskell, T & Blackburn, C C 2016, ' Foxn1 Is Dynamically Regulated in Thymic Epithelial Cells during Embryogenesis and at the Onset of Thymic Involution ', PLoS ONE, vol. 11, no. 3, pp. e0151666 . https://doi.org/10.1371/journal.pone.0151666
Thymus function requires extensive cross-talk between developing T-cells and the thymic epithelium, which consists of cortical and medullary TEC. The transcription factor FOXN1 is the master regulator of TEC differentiation and function, and declinin
Autor:
Pascal D. Odermatt, Georg E. Fantner, Freddy Radtke, Yann Barrandon, Luca Azzolin, Craig S. Nowell, Sylke Hohnel, Stefano Piccolo, Matthias P. Lutolf, Erwin F. Wagner
Publikováno v:
Nature Cell Biology
Chronic inflammation is associated with a variety of pathological conditions in epithelial tissues, including cancer, metaplasia and aberrant wound healing. In relation to this, a significant body of evidence suggests that aberration of epithelial st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c631c1dbde89afc8d87d378a76639906
http://hdl.handle.net/11577/3220622
http://hdl.handle.net/11577/3220622
Autor:
Grant Morahan, Frances H. Stenhouse, Simon R. Tomlinson, Kevin A. Robertson, Natalie F. Blair, Adelina Pagliocca, Alison Farley, Terri Gaskell, C. Clare Blackburn, Craig S. Nowell, Marianne G. L. Depreter, Kathleen Davern, Adrian Fraser, Jan Vrána
Publikováno v:
Depreter, M G L, Blair, N F, Gaskell, T L, Nowell, C S, Davern, K, Pagliocca, A, Stenhouse, F H, Farley, A M, Fraser, A, Vrana, J, Robertson, K, Morahan, G, Tomlinson, S R & Blackburn, C C 2008, ' Identification of Plet-1 as a specific marker of early thymic epithelial progenitor cells ', Proceedings of the National Academy of Sciences, vol. 105, no. 3, pp. 961–966 . https://doi.org/10.1073/pnas.0711170105
The thymus is essential for a functional immune system, because the thymic stroma uniquely supports T lymphocyte development. We have previously identified the epithelial progenitor population from which the thymus arises and demonstrated its ability
Autor:
Freddy Radtke, Craig S. Nowell
Publikováno v:
Cell Cycle. 15:1393-1394
Keywords: inflammation ; stem cells ; mechanotransduction ; tissue repair ; cancer Reference EPFL-ARTICLE-221997doi:10.1080/15384101.2016.1171645View record in Web of Science Record created on 2016-10-18, modified on 2017-05-12