Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Craig R. Rayner"'
Publikováno v:
Infectious Diseases and Therapy, Vol 9, Iss 4, Pp 715-720 (2020)
Abstract Antivirals have demonstrated efficacy in treating other infectious diseases in early stages of disease, reducing morbidity, mortality, and the likelihood of onward transmission. At the time of writing, more than 1900 clinical trials are regi
Externí odkaz:
https://doaj.org/article/8c61aa5422a14a1782d4df8923662dec
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 5, Pp 830-834 (2020)
Externí odkaz:
https://doaj.org/article/671bf3a0425e443abe4c696b3dfe92d1
Autor:
Gilmar Reis, Eduardo Augusto dos Santos Moreira Silva, Daniela Carla Medeiros Silva, Lehana Thabane, Aline Cruz Milagres, Thiago Santiago Ferreira, Castilho Vitor Quirino dos Santos, Adhemar Dias de Figueiredo Neto, Eduardo Diniz Callegari, Leonardo Cançado Monteiro Savassi, Maria Izabel Campos Simplicio, Luciene Barra Ribeiro, Rosemary Oliveira, Ofir Harari, Holly Bailey, Jamie I Forrest, Alla Glushchenko, Sheila Sprague, Paula McKay, Craig R. Rayner, Hinda Ruton, Gordon H. Guyatt, Edward J. Mills
Publikováno v:
The Lancet Regional Health. Americas, Vol 6, Iss , Pp 100142- (2022)
Summary: Background: Observational studies have postulated a therapeutic role of metformin in treating COVID-19. We conducted an adaptive platform clinical trial to determine whether metformin is an effective treatment for high-risk patients with ear
Externí odkaz:
https://doaj.org/article/c787b7addd6647dbaccfffc94732bfc7
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 4, Pp 646-648 (2020)
The global response to finding therapeutics for coronavirus disease 2019 (COVID‐19) is chaotic even if well intentioned. There is an opportunity, but more importantly, an obligation for the global clinical and quantitative pharmacology community to
Externí odkaz:
https://doaj.org/article/5b16b0e90d9a48b9b6b359ff909525e7
Autor:
Nolan D Wood, Danelle Smith, Sally A Kinrade, Mark T Sullivan, Craig R Rayner, David Wesche, Kashyap Patel, Karen Rowland-Yeo
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 8, p e0012351 (2024)
Moxidectin is approved by the US Food and Drug Administration (US FDA) for the treatment of onchocerciasis (river-blindness) due to Onchocerca volvulus in patients aged 12 years and older. In onchocerciasis-endemic areas, mass drug administration (MD
Externí odkaz:
https://doaj.org/article/9212bc1a647c428a840979071a3a8867
Autor:
Gilmar Reis, Eduardo A.S. Moreira Silva, Daniela C. Medeiros Silva, Lehana Thabane, Vitoria H.S. Campos, Thiago S. Ferreira, Castilho V.Q. Santos, Ana M.R. Nogueira, Ana P.F.G. Almeida, Leonardo C.M. Savassi, Adhemar D. Figueiredo-Neto, Ana C.F. Dias, Adelino M. Freire Júnior, Carina Bitarães, Aline C. Milagres, Eduardo D. Callegari, Maria I.C. Simplicio, Luciene B. Ribeiro, Rosemary Oliveira, Ofir Harari, Lindsay A. Wilson, Jamie I. Forrest, Hinda Ruton, Sheila Sprague, Paula McKay, Christina M. Guo, Eve H. Limbrick-Oldfield, Steve Kanters, Gordon H. Guyatt, Craig R. Rayner, Christopher Kandel, Mia J. Biondi, Robert Kozak, Bettina Hansen, M. Atif Zahoor, Paul Arora, Colin Hislop, Ingrid Choong, Jordan J. Feld, Edward J. Mills, Jeffrey S. Glenn
Publikováno v:
New England Journal of Medicine, 388(6), 518-528. Massachussetts Medical Society
Background: The efficacy of a single dose of pegylated interferon lambda in preventing clinical events among outpatients with acute symptomatic coronavirus disease 2019 (Covid-19) is unclear. Methods: We conducted a randomized, controlled, adaptive p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c288aadca6896e75715728f1c300fd0c
https://pure.eur.nl/en/publications/6ba613d8-30ae-4490-8521-6e257ffce196
https://pure.eur.nl/en/publications/6ba613d8-30ae-4490-8521-6e257ffce196
Autor:
Edward J Mills, Jason A. Roberts, Alex Lepak, Debra Hanna, Mark J. Shelton, Kayla Ann Andrews, Craig R. Rayner, Lena E. Friberg, Patrick F. Smith, David Wesche, David R. Andes, Karen Rowland‐Yeo, Hartmut Derendorf, Virna J A Schuck, Thomas M. Polasek
Publikováno v:
Clinical Pharmacology and Therapeutics
Model-informed drug development (MIDD) has a long and rich history in infectious diseases. This review describes foundational principles of translational anti-infective pharmacology, including choice of appropriate measures of exposure and pharmacody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da6a3ebd42760e80ec87464af056198
https://doi.org/10.1002/cpt.2198
https://doi.org/10.1002/cpt.2198
Autor:
Edward J Mills, Craig R. Rayner, Jamie I Forrest, Zelyn Lee, Jean B. Nachega, Esha Senchaudhuri
Publikováno v:
The American Journal of Tropical Medicine and Hygiene
The efficacy and safety of hydroxychloroquine (HCQ) for the prevention and treatment of COVID-19 has received great attention, and most notably, the enthusiasm for HCQ has been one of politicization rather than science. Laboratory studies and case se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b1dd421195d4e0018f0114b49dff68
https://doi.org/10.4269/ajtmh.20-1320
https://doi.org/10.4269/ajtmh.20-1320
Autor:
Noor-E Zannat, Gerald Smith, Grace Hsu, Craig R Rayner, Louis Dron, Paul Arora, Eric Mackay, Alison Dillman, Alind Gupta, Jay J H Park, Edward J Mills, Michael J. Zoratti, Zelyn Lee, Ofir Harari
Publikováno v:
Infection and Drug Resistance
Alison Dillman,1 Michael J Zoratti,2 Jay JH Park,3 Grace Hsu,2 Louis Dron,2 Gerald Smith,2 Ofir Harari,2 Craig R Rayner,4 Noor-E Zannat,2 Alind Gupta,2 Eric Mackay,5 Paul Arora,6 Zelyn Lee,7 Edward J Mills2 1School of Public Health, Faculty of Medici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8eb09b744e06dce2261ff9598a5dba5
https://doi.org/10.2147/idr.s288399
https://doi.org/10.2147/idr.s288399
Autor:
Gilmar, Reis, Eduardo A S M, Silva, Daniela C M, Silva, Lehana, Thabane, Aline C, Milagres, Thiago S, Ferreira, Castilho V Q, Dos Santos, Vitoria H S, Campos, Ana M R, Nogueira, Ana P F G, de Almeida, Eduardo D, Callegari, Adhemar D F, Neto, Leonardo C M, Savassi, Maria I C, Simplicio, Luciene B, Ribeiro, Rosemary, Oliveira, Ofir, Harari, Jamie I, Forrest, Hinda, Ruton, Sheila, Sprague, Paula, McKay, Christina M, Guo, Karen, Rowland-Yeo, Gordon H, Guyatt, David R, Boulware, Craig R, Rayner, Edward J, Mills, Túlio, Fonseca E Silva Quadros
Publikováno v:
The New England journal of medicine. 386(18)
The efficacy of ivermectin in preventing hospitalization or extended observation in an emergency setting among outpatients with acutely symptomatic coronavirus disease 2019 (Covid-19), the disease caused by severe acute respiratory syndrome coronavir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b00a060782dbed00a1f3a2b2a07ccbe7
https://pubmed.ncbi.nlm.nih.gov/36516104
https://pubmed.ncbi.nlm.nih.gov/36516104