Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Craig R, Lee"'
Autor:
Larisa H. Cavallari, Craig R. Lee, Francesco Franchi, Ellen C. Keeley, Joseph S. Rossi, Cameron D. Thomas, Yan Gong, Caitrin W. McDonough, Petr Starostik, Maryam J. Al Saeed, Latonya Been, Natasha Kulick, Jean Malave, Ian R. Mulrenin, Anh B. Nguyen, Joshua N. Terrell, Grace Tillotson, Amber L. Beitelshees, Almut G. Winterstein, George A. Stouffer, Dominick J. Angiolillo
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 8, Pp n/a-n/a (2024)
Abstract Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 receptor inhibitor (clopidogrel, prasugrel, or ticagrelor) is indicated after percutaneous coronary intervention (PCI) to reduce the risk of atherothrombotic events. Approximately 30%
Externí odkaz:
https://doaj.org/article/7b075fa5eb614f1a8179175d280beddf
Autor:
Kayla R. Tunehag, Cameron D. Thomas, Francesco Franchi, Joseph S. Rossi, Ellen C. Keeley, R. David Anderson, Amber L. Beitelshees, Julio D. Duarte, Yan Gong, Richard A. Kerensky, Caitrin W. McDonough, Anh B. Nguyen, Luis Ortega‐Paz, Sanjay Venkatesh, Yehua Wang, Julie A. Johnson, Almut G. Winterstein, George A. Stouffer, Dominick J. Angiolillo, Larisa H. Cavallari, Craig R. Lee
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 12 (2024)
Background Cytochrome P450 2C19 (CYP2C19) intermediate and poor metabolizer patients exhibit diminished clopidogrel clinical effectiveness after percutaneous coronary intervention (PCI). However, outcome studies to date have lacked racial diversity.
Externí odkaz:
https://doaj.org/article/50016bae702e4bcbb5b7ae35deb0f244
Autor:
Julian E. Garcia, Ian R. Mulrenin, Anh B. Nguyen, Matthew S. Loop, Melissa A. Daubert, Rachel Urrutia, Craig R. Lee
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Hypertensive disorders of pregnancy (HDP) are rising in prevalence and associated with adverse maternal and infant health outcomes. Current guidelines recommend labetalol, nifedipine, and methyldopa as acceptable first-line agents to treat HDP in out
Externí odkaz:
https://doaj.org/article/7590f87bd754486a82906f2f0a359439
Autor:
Muluneh M. Fashe, Taryn A. Miner, John K. Fallon, Amanda P. Schauer, Craig Sykes, Philip C. Smith, Craig R. Lee
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Pregnancy increases the clearance of CYP3A4 substrate drugs and pregnancy-related hormones (PRHs) induce hepatic CYP3A4 expression and metabolism. However, it remains unclear to what extent the magnitude of PRH-evoked changes in hepatic
Externí odkaz:
https://doaj.org/article/5bf5aea07c3d46e3afd836d8b7b04fe3
Autor:
Muluneh M. Fashe, John K. Fallon, Taryn A. Miner, Jacqueline B. Tiley, Philip C. Smith, Craig R. Lee
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Pregnancy alters the disposition and exposure to multiple drugs indicated for pregnancy-related complications. Previous in vitro studies have shown that pregnancy-related hormones (PRHs) alter the expression and function of certain cytochrome P450s (
Externí odkaz:
https://doaj.org/article/1e6c5b0acbba40869e4315e3c168bd86
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Dual antiplatelet therapy with a P2Y12 inhibitor (clopidogrel, prasugrel, or ticagrelor) and aspirin remains the standard of care for all patients undergoing percutaneous coronary intervention (PCI). It is well-established that patients carrying CYP2
Externí odkaz:
https://doaj.org/article/32b6f9ead6864846850e7649e32d9567
Autor:
Amber L. Beitelshees, Cameron D. Thomas, Philip E. Empey, George A. Stouffer, Dominick J. Angiolillo, Francesco Franchi, Sony Tuteja, Nita A. Limdi, James C. Lee, Julio D. Duarte, Rolf P. Kreutz, Todd C. Skaar, James C. Coons, Jay Giri, Caitrin W. McDonough, Rachel Rowland, James M. Stevenson, Thuy Thai, Mark R. Vesely, Jacob T. Wellen, Julie A. Johnson, Almut G. Winterstein, Larisa H. Cavallari, Craig R. Lee
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 4 (2022)
Background Studies have demonstrated increased risk of major atherothrombotic events in CYP2C19 loss‐of‐function (LOF) variant carriers versus non‐carriers treated with clopidogrel after percutaneous coronary intervention (PCI). We sought to ev
Externí odkaz:
https://doaj.org/article/fdde104f3e8e43f68d0603d9571a4e08
Autor:
José A. G. Agúndez, Christine Formea, Andrea Gaedigk, Elena García-Martín, Li Gong, Tilo Grosser, Craig R. Lee, Katherine N. Theken
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/0c2925f6a2994ecd9cf74f9d68333cd1
Autor:
Raju Khatri, John K. Fallon, Craig Sykes, Natasha Kulick, Rebecca J. B. Rementer, Taryn A. Miner, Amanda P. Schauer, Angela D. M. Kashuba, Kim A. Boggess, Kim L. R. Brouwer, Philip C. Smith, Craig R. Lee
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Pregnancy-related hormones (PRH) are recognized as important regulators of hepatic cytochrome P450 enzyme expression and function. However, the impact of PRH on the hepatic expression and function of uridine diphosphate glucuronosyltransferases (UGTs
Externí odkaz:
https://doaj.org/article/4cac6828a3614bad9e8e1bd1b1e4fcc3
Publikováno v:
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 43:158-175
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82491bd597ab816483251438a236d19c
https://doi.org/10.1002/phar.2758
https://doi.org/10.1002/phar.2758