Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Craig Okada"'
Autor:
Swaminathan P. Iyer, Auris Huen, Weiyun Z. Ai, Deepa Jagadeesh, Mary J. Lechowicz, Craig Okada, Tatyana A. Feldman, Paola Ghione, Juan P. Alderuccio, Rebecca Champion, Seo-Hyun Kim, Ann Mohrbacher, Kasi V. Routhu, Prajak Barde, Ajit M. Nair, Bradley M. Haverkos
Publikováno v:
Haematologica, Vol 109, Iss 1 (2023)
Tenalisib, a selective phosphoinositide-3-kinase δ/γ, and salt-inducible-kinase-3 inhibitor has shown efficacy and was well-tolerated in patients with T-cell lymphoma (TCL). In vitro studies suggest a synergistic anti-tumor potential for the combin
Externí odkaz:
https://doaj.org/article/e5c3577369044e1e834302358c57d097
Autor:
Adam S. Kittai, Scott Best, Bria Thurlow, Vi Lam, Taylor Hashiguchi, Shaun Goodyear, Daniel O. Persky, Craig Okada, Byung Park, Stephen E. Spurgeon, Alexey V. Danilov
Publikováno v:
Haematologica, Vol 106, Iss 7 (2021)
Externí odkaz:
https://doaj.org/article/831868bb6ee24e4dad3f1c03097fdbda
Autor:
Stephen E. Spurgeon, Guang Fan, Alexey V. Danilov, Craig Okada, Adam Kittai, Vikram Raghunathan
Publikováno v:
European Journal of Haematology. 106:294-297
The treatment of chronic lymphocytic leukemia (CLL) has been transformed by the use of targeted small molecules inhibiting components of the B cell receptor (BCR) signaling pathway (Haematologica, 103, 2018 and e204; Curr Hematol Malig Rep, 14, 2019,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e528bc6186d58211b7bca752b63e2e1d
https://doi.org/10.1111/ejh.13538
https://doi.org/10.1111/ejh.13538
Autor:
Derek Galligan, Staci Williamson, Jessie Myers, Robert Ahrenkiel, Chi Phan, Levanto Schachter, Andy I. Chen, Brandon Hayes-Lattin, Craig Okada, Stephen Spurgeon, Richard T Maziarz
Publikováno v:
Transplantation and Cellular Therapy. 28:S422-S423
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1eb7a67b9956bb0cded8e3087cc28ff
https://doi.org/10.1016/s2666-6367(22)00700-x
https://doi.org/10.1016/s2666-6367(22)00700-x
Autor:
Ian W. Flinn, Yaping Shou, Bob Uger, James M. Foran, Mary-Elizabeth M. Percival, Diego Villa, Kathleen Large, Catherine Diefenbach, Stephen M. Ansell, Youn H. Kim, Ahmed Sawas, Craig Okada, Kerry J. Savage, Gloria H. Y. Lin, Tatyana Feldman, Oleg E. Akilov, Steven M. Horwitz, Michael B. Maris, Lubomir Sokol, Mark D. Minden, Deepa Jagadeesh, Penka S. Petrova, Tina Catalano, Matthew Mei, Naomi Molloy
Publikováno v:
Blood. 136:41-43
Background CD47 is an innate immune checkpoint that binds signal regulatory protein alpha (SIRPα) and delivers a "do not eat" signal to suppress macrophage phagocytosis. Overexpression of CD47 can allow tumor cells to escape immune surveillance. TTI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f74fb340da5447e4b0bad7b1d9d8c56
https://doi.org/10.1182/blood-2020-136198
https://doi.org/10.1182/blood-2020-136198
Autor:
Don A. Stevens, Suchitra Sundaram, Swami P. Iyer, Auris Huen, Mary Jo Lechowicz, Weiyun Z. Ai, Tatyana Feldman, Craig Okada, Juan Pablo Alderuccio, Ann Mohrbacher, Bradley M. Haverkos, Timothy M. Kuzel, Ajit Nair, Kasi V. Routhu, Deepa Jagadeesh, Ryan A. Wilcox, Prajak J Barde, Nishitha Reddy
Publikováno v:
Blood. 136:8-10
Background: T cell lymphomas (TCL) have been known to exhibit epigenetic dysregulation and aberrant cell signaling. Tenalisib (RP6530), a highly selective PI3K δ/γ+SIK3 inhibitor has shown clinically promising activity as a single agent in TCL with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76068380245d532b4f7f33cc9950b977
https://doi.org/10.1182/blood-2020-136018
https://doi.org/10.1182/blood-2020-136018
Autor:
Steven M. Horwitz, James M. Foran, Michael Maris, Jennifer Kimberly Lue, Ahmed Sawas, Craig Okada, Tatyana A. Feldman, Lubomir Sokol, Matthew Mei, Ian W. Flinn, Diego Villa, Mary-Elizabeth M. Percival, Deepa Jagadeesh, Kerry J. Savage, Oleg Akilov, Catherine S. Diefenbach, Youn H. Kim, Gloria H. Y. Lin, Tina Catalano, Penka S. Petrova, Bob Uger, Naomi Molloy, Kathleen Large, Ingmar Bruns, Stephen M. Ansell
Publikováno v:
Blood. 138:2448-2448
Background CD47 is an innate immune checkpoint that binds signal regulatory protein alpha (SIRPα) and delivers a "don't eat me" signal to suppress macrophage phagocytosis. Overexpression of CD47 can allow tumor cells to escape immune surveillance. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ead7b618008154e89e3c2a7f394ef4d9
https://doi.org/10.1182/blood-2021-154490
https://doi.org/10.1182/blood-2021-154490
Autor:
Jasmine Zain, Lisa Johnson, Christiane Querfeld, Robert A. Uger, Swati Banerjee, Oleg Kruglov, Mark Wong, Natasja Nielsen Viller, Owen A. O'Connor, Steven M. Horwitz, Yaping Shou, Robert T. Chen, Craig Okada, Eric L. Sievers, Alexander M. Lesokhin, Oleg E. Akilov, Ahmed Sawas
Publikováno v:
Blood advances. 3(7)
Sézary syndrome (SS), the leukemic variant of cutaneous T-cell lymphoma, has limited treatment options and rare occurrences of long-term remission, thus warranting research into new treatment approaches. CD47 has emerged as a promising target for mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61c2c66297ec588aff22b50c5e7875ea
https://pubmed.ncbi.nlm.nih.gov/30962222
https://pubmed.ncbi.nlm.nih.gov/30962222
Autor:
Craig Okada, Alexey V. Danilov, Nur Bruss, Allison Berger, Cody Paiva, Tingting Liu, Adam Kittai, Scott R Best, Taylor Hashiguchi
Publikováno v:
Blood advances. 3(1)
Alterations in the ubiquitin proteasome system (UPS) leave malignant cells in heightened cellular stress, making them susceptible to proteasome inhibition. However, given the limited efficacy of proteasome inhibitors in non-Hodgkin lymphoma (NHL), no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36030279c4957bc4c62eadfb0d008363
https://pubmed.ncbi.nlm.nih.gov/30617217
https://pubmed.ncbi.nlm.nih.gov/30617217
Publikováno v:
Clinics in colon and rectal surgery. 31(5)
Non-Hodgkin lymphoma (NHL) that primarily involves the colon is rare and should be distinguished from the more common systemic nodal lymphoma. It has unique clinical expectations and management consideration. Different histologic subtypes of NHL invo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c810dc8687876b2b6ae2e7e8fad9ef
https://pubmed.ncbi.nlm.nih.gov/30186053
https://pubmed.ncbi.nlm.nih.gov/30186053