Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Craig Murdoch"'
Publikováno v:
Biomaterial Investigations in Dentistry, Vol 7, Iss 1, Pp 146-157 (2020)
Objectives To investigate if differences in titanium implant surface topography influence Candida albicans biofilm formation. Materials and Methods Titanium discs were prepared and characterized using a profilometer: Group A (Ra 0.15 µm, smooth), Gr
Externí odkaz:
https://doaj.org/article/95982e89ad5a4a8286a6e9c29ebef018
Publikováno v:
Frontiers in Oral Health, Vol 2 (2021)
Decades ago, the study of cancer biology was mainly focused on the tumor itself, paying little attention to the tumor microenvironment (TME). Currently, it is well recognized that the TME plays a vital role in cancer development and progression, with
Externí odkaz:
https://doaj.org/article/4779c79579ae4dc1ae02bae25336a035
Autor:
Amy L. Harding, Craig Murdoch, Simon Danby, Md Zobaer Hasan, Hirofumi Nakanishi, Tetsuo Furuno, Sirwan Hadad, Robert Turner, Helen E. Colley
Publikováno v:
JID Innovations, Vol 1, Iss 2, Pp 100011- (2021)
There are no physical or visual manifestations that define skin sensitivity or irritation; a subjective diagnosis is made on the basis of the evaluation of clinical presentations, including burning, prickling, erythema, and itching. Adverse skin reac
Externí odkaz:
https://doaj.org/article/c3b826496c984778b2a6f8ac07f8d4d0
Autor:
Sabrina Barbosa de Souza Ferreira, Gustavo Braga, Évelin Lemos Oliveira, Jéssica Bassi da Silva, Hélen Cássia Rosseto, Lidiane Vizioli de Castro Hoshino, Mauro Luciano Baesso, Wilker Caetano, Craig Murdoch, Helen Elizabeth Colley, Marcos Luciano Bruschi
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 10, Iss 1, Pp 2304-2328 (2019)
Mucoadhesive nanostructured systems comprising poloxamer 407 and Carbopol 974P® have already demonstrated good mucoadhesion, as well as improved mechanical and rheological properties. Curcumin displays excellent biological activity, mainly in oral s
Externí odkaz:
https://doaj.org/article/42509663bb1b48938dafb94ccd57250a
Publikováno v:
Sensors, Vol 22, Iss 15, p 5913 (2022)
A multiscale modelling approach has been applied to the simulation of the electrical properties of oral tissue, for the purpose of informing an electrical impedance-based method of oral potential malignant disorder (OPMD) diagnosis. Finite element mo
Externí odkaz:
https://doaj.org/article/2fb55f937d7d4d7bb424773586d43c82
Autor:
Hannah West, Fiona Roberts, Paul Sweeney, Simon Walker-Samuel, Joseph Leedale, Helen Colley, Craig Murdoch, Rebecca J Shipley, Steven Webb
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254208 (2021)
Nanoparticles have the potential to increase the efficacy of anticancer drugs whilst reducing off-target side effects. However, there remain uncertainties regarding the cellular uptake kinetics of nanoparticles which could have implications for nanop
Externí odkaz:
https://doaj.org/article/81b955807a9144d8933128dc95e0bd7e
Autor:
Joseph Leedale, Kieran J. Sharkey, Helen E. Colley, Áine M. Norton, David Peeney, Chantelle L. Mason, Jean G. Sathish, Craig Murdoch, Parveen Sharma, Steven D. Webb
Publikováno v:
iScience, Vol 4, Iss , Pp 84-96 (2018)
Summary: Many xenobiotics can bind to off-target receptors and cause toxicity via the dysregulation of downstream transcription factors. Identification of subsequent off-target toxicity in these chemicals has often required extensive chemical testing
Externí odkaz:
https://doaj.org/article/7a4f13c9f84141ecb44712980aa71c4a
Autor:
Lauren Tomlinson, Zhen Qi Lu, Robert A Bentley, Helen E. Colley, Craig Murdoch, Steven D. Webb, Michael J. Cross, Ian M. Copple, Parveen Sharma
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 112, Iss , Pp - (2019)
Dose-dependent cardiotoxicity is the leading adverse reaction seen in cancer patients treated with doxorubicin. Currently, dexrazoxane is the only approved drug that can partially protect against this toxicity in patients, however, its administration
Externí odkaz:
https://doaj.org/article/0819abf2d1dc48ffad04323516400d66
Autor:
Jake G. Edmans, Katharina H. Clitherow, Craig Murdoch, Paul V. Hatton, Sebastian G. Spain, Helen E. Colley
Publikováno v:
Pharmaceutics, Vol 12, Iss 6, p 504 (2020)
Oral disease greatly affects quality of life, as the mouth is required for a wide range of activities including speech, food and liquid consumption. Treatment of oral disease is greatly limited by the dose forms that are currently available, which su
Externí odkaz:
https://doaj.org/article/f84ba2387e9042608933f5283da5ca5f
Autor:
Jessica C. Pahler, Simon Tazzyman, Neta Erez, Yung-Yi Chen, Craig Murdoch, Hiroaki Nozawa, Claire E. Lewis, Douglas Hanahan
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 4, Pp 329-339 (2008)
Previous studies in the K14-HPV/E2 mouse model of cervical carcinogenesis demonstrated that infiltrating macrophages are the major source of matrix metalloproteinase 9 (MMP-9), a metalloprotease important for tumor angiogenesis and progression. We ob
Externí odkaz:
https://doaj.org/article/7453dfefe22447028abca372c2f0fa42