Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Craig M. Sorensen"'
Autor:
Craig M. Sorensen, Stanley J. Korsmeyer, Gabriel Núñez, Timothy J. McDonnell, David M. Hockenbery
Publikováno v:
Nature. 353:71-73
The number of lymphocytes in an animal is remarkably constant despite antigen-driven proliferation and a high rate of B-cell lymphopoiesis. This reflects the relatively brief lifespan of many newly generated B cells and argues for a well-regulated de
Publikováno v:
Brain research bulletin. 34(1)
We and others have reported that c-fos protein is induced in the hypothalamus and brain stem of the rat following central and peripheral injections of endotoxin (lipopolysaccharide; LPS). We have now examined possible mechanisms through which LPS ind
Autor:
Catherine Y. Vriend, Craig M. Sorensen, Arnold H. Greenberg, Weihua Wan, Loren Janz, Dwight M. Nance
Publikováno v:
Brain research bulletin. 32(6)
Lipopolysaccharide (LPS), an endotoxin associated with gram-negative bacteria, is a potent activator of the immune system. We have tested the effects of ICV infusions of LPS (10 ng) or Ringer's solution on the induction of the proto-oncogene protein
Publikováno v:
Hospital Practice. 19:85-98
Considerable progress has been made in achieving immunosuppression pharmacologically, but because specificity is lacking, the patient is often rendered highly susceptible to infection. On the basis of major advances toward characterizing the biochemi
Publikováno v:
The Journal of Experimental Medicine
We have previously reported that two types of suppressor T cell factors (TsF) specific for L-glutamic acid50-L-tyrosine50 (GT) or L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) can be distinguished based upon differences in their ability to suppres
Autor:
Craig M. Sorensen, Carl W. Pierce
Publikováno v:
The Journal of Experimental Medicine
Spleen cells from C57BL/10 mice injected with syngeneic B10 L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT)-pulsed macrophages (GAT-M phi) within 18 h of birth were unable to respond to soluble GAT, GAT-methylated bovine serum albumin, or B10 GAT-M
Publikováno v:
The Journal of Experimental Medicine
A hybridoma-derived, GAT-specific suppressor T cell factor (GAT-TsFR) from responder C57BL/10 mice has been purified to apparent chemical homogeneity using reversed phase HPLC techniques. 40 l of starting material yielded approximately 880 micrograms
Autor:
Craig M. Sorensen, Carl W. Pierce
Publikováno v:
The Journal of Experimental Medicine
C57BL/10 mice were injected with semiallogeneic (B10.D2 X C57BL/10)F(1) spleen cells via the anterior facial vein within 24 h of birth to induce tolerance to B10.D2 (H-2(d)) alloantigens. Spleen cells from these mice as adults developed reduced, but
Publikováno v:
Methods in Enzymology ISBN: 9780121820169
Publisher Summary This chapter discusses the antigen-specific suppressor factors from hybridoma cell lines. Given the extreme heterogeneity of T cell subsets and the number of antigenic specificities that each subset can recognize, T cell receptors a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa35eb09476317bd4d21708ff28a94b2
https://doi.org/10.1016/s0076-6879(85)16024-6
https://doi.org/10.1016/s0076-6879(85)16024-6