Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Craig M. Hart"'
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205538 (2018)
An engineered phiC31 "Disintegrase" able to make an attP site in Drosophila out of an attR-attL pair is described. This was used to generate attP sites at genomic locations where a mini-white (mini-w) transgene was subject to chromosomal position eff
Externí odkaz:
https://doaj.org/article/ad394c8d7ed84fe19ef40f3b4d265cd4
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0203843 (2018)
Chromatin organization is crucial for nuclear functions such as gene regulation, DNA replication and DNA repair. Insulator binding proteins, such as the Drosophila Boundary Element-Associated Factor (BEAF), are involved in chromatin organization. To
Externí odkaz:
https://doaj.org/article/bda2cec1c63b47c689af2da6025780de
Autor:
J Keller McKowen, Satya V S P Avva, Mukesh Maharjan, Fabiana M Duarte, Jacob M Tome, Julius Judd, Jamie L Wood, Sunday Negedu, Yunkai Dong, John T Lis, Craig M Hart
Publikováno v:
G3 Genes|Genomes|Genetics. 12
The Drosophila Boundary Element-Associated Factor of 32 kDa (BEAF) binds in promoter regions of a few thousand mostly housekeeping genes. BEAF is implicated in both chromatin domain boundary activity and promoter function, although molecular mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c8479065813c2856530dd7fe1db5ae9
https://doi.org/10.1093/g3journal/jkac223
https://doi.org/10.1093/g3journal/jkac223
Autor:
S V Satya Prakash Avva, Craig M Hart
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162906 (2016)
Data implicate the Drosophila 32 kDa Boundary Element-Associated Factors BEAF-32A and BEAF-32B in both chromatin domain insulator element function and promoter function. They might also function as an epigenetic memory by remaining bound to mitotic c
Externí odkaz:
https://doaj.org/article/9a11efe3e7be41fd9682b4a8e49c9726
Publikováno v:
Genetics. 215:1003-1012
Chromatin domain insulators are thought to help partition the genome into genetic units called topologically associating domains (TADs). In Drosophila, TADs are often separated by inter-TAD regions containing active housekeeping genes and associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdcdfa3e20f287f8426902f6cbadd343
https://doi.org/10.1534/genetics.120.303344
https://doi.org/10.1534/genetics.120.303344
Autor:
Eldon Emberly, Roxane Blattes, Bernd Schuettengruber, Magali Hennion, Nan Jiang, Craig M Hart, Emmanuel Käs, Olivier Cuvier
Publikováno v:
PLoS Biology, Vol 6, Iss 12, Pp 2896-2910 (2008)
Chromatin insulators/boundary elements share the ability to insulate a transgene from its chromosomal context by blocking promiscuous enhancer-promoter interactions and heterochromatin spreading. Several insulating factors target different DNA consen
Externí odkaz:
https://doaj.org/article/9e4ba87f91dd4db389a25d3c7c5aa349
Publikováno v:
Genetics
Chromatin domain insulators are thought to help partition the genome into genetic units called topologically associating domains (TADs). In Drosophila, TADs are often separated by inter-TAD regions containing active housekeeping genes and associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ccfe61907faab39ead3c6b765ead401
https://pubmed.ncbi.nlm.nih.gov/32554599
https://pubmed.ncbi.nlm.nih.gov/32554599
Autor:
Eldon Emberly, Roxane Blattes, Bernd Schuettengruber, Magali Hennion, Nan Jiang, Craig M Hart, Emmanuel Käs, Olivier Cuvier
Publikováno v:
PLoS Biology, Vol 7, Iss 6 (2009)
Externí odkaz:
https://doaj.org/article/478121afcf954e2eb9038aa90f06a5e2
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 10, p e0205538 (2018)
PLoS ONE, Vol 13, Iss 10, p e0205538 (2018)
An engineered phiC31 "Disintegrase" able to make an attP site in Drosophila out of an attR-attL pair is described. This was used to generate attP sites at genomic locations where a mini-white (mini-w) transgene was subject to chromosomal position eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc4fbd70ff915c62e87e424691213c0
https://pubmed.ncbi.nlm.nih.gov/30296303
https://pubmed.ncbi.nlm.nih.gov/30296303
Autor:
Nan Jiang, Bing He, Craig M. Hart, Pamela K. Geyer, Kai Tan, Alexey A. Soshnev, Ryan M. Baxley
Publikováno v:
Nucleic Acids Research
The Drosophila Suppressor of Hairy-wing [Su(Hw)] protein is a globally expressed, multi-zinc finger (ZnF) DNA-binding protein. Su(Hw) forms a classic insulator when bound to the gypsy retrotransposon and is essential for female germline development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8209e78c9543cfef59d49ef22daf825
http://europepmc.org/articles/PMC3384341
http://europepmc.org/articles/PMC3384341