Zobrazeno 1 - 10
of 216
pro vyhledávání: '"Craig Lockhart"'
Autor:
Jingyuan Wang, Joanne Xiu, Francesca Battaglin, Hiroyuki Arai, Shivani Soni, Wu Zhang, Richard M. Goldberg, Philip A. Philip, Andreas Seeber, Jimmy J. Hwang, Anthony F. Shields, John L. Marshall, Igor Astaturov, Tianshu Liu, A. Craig Lockhart, W. Michael Korn, Lin Shen, Heinz-Josef Lenz
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-10 (2024)
Abstract Although histological and molecular classifications have been extensively studied for gastric cancer (GC), targeted therapies for GC remain limited. CDH1 mutations (MT) are characteristic of genomically stable GC and are associated with poor
Externí odkaz:
https://doaj.org/article/a3d469c1d6cf430091e90de7ea2adb8c
Autor:
Gregory Vlacich, Andrew Ballard, Shahed N. Badiyan, Matthew Spraker, Lauren Henke, Hyun Kim, A. Craig Lockhart, Haeseong Park, Rama Suresh, Yi Huang, Cliff G. Robinson, Jeffrey D. Bradley, Pamela P. Samson
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 30, Iss , Pp 19-25 (2021)
Background and purpose: Radiation dose escalation to improve poor outcomes with chemoradiation in locally advanced esophageal carcinoma is limited in part by increased toxicity. This Phase I study investigates the use of IMRT to improve tolerability
Externí odkaz:
https://doaj.org/article/579195d4e48d41639f46f0992f183039
Autor:
Takashi Kojima, Sung-Bae Kim, Ken Kato, Antoine Hollebecque, Per Pfeiffer, Florian Lordick, Masahiro Tajika, Mark Ayers, Jared Lunceford, Manish Shah, Daniel Hochhauser, Peter Enzinger, Judith Raimbourg, Heung Tae Kim, A Craig Lockhart, Hendrick-Tobias Arkenau, Farid El-Hajbi, Pooja Bhagia, Z Alexander Cao, Shailaja Suryawanshi, Matt Marton
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/df03b38851d04671bfca314d3e6727c1
Autor:
Manish A Shah, Takashi Kojima, Daniel Hochhauser, Peter Enzinger, Judith Raimbourg, Antoine Hollebecque, Florian Lordick, Sung-Bae Kim, Masahiro Tajika, Albert Craig Lockhart, Hendrick-Tobias Arkenau, Farid El-Hajbi, Mukul Gupta, Per Pfeiffer, Pooja Bhagia, Zhu Alexander Cao, Jared Lunceford, Shailaja Suryawanshi, Mark Ayers, Matthew J Marton, Ken Kato
Publikováno v:
Future Oncology. 18:2783-2790
Aim: Investigate the relationship between response to pembrolizumab and expression of the 18-gene T cell-inflamed gene expression profile (TcellinfGEP) or PD-L1 combined positive score (CPS) in esophageal cancer. Materials & methods: This analysis in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0968c9a4709802993be2af484ebd32e
https://doi.org/10.2217/fon-2021-1134
https://doi.org/10.2217/fon-2021-1134
Autor:
Ling Zhang, Clara I. Troccoli, Beatriz Mateo-Victoriano, Laura Misiara Lincheta, Erin Jackson, Ping Shu, Trisha Plastini, Wensi Tao, Deukwoo Kwon, Xi Chen, Janaki Sharma, Merce Jorda, James L. Gulley, Marijo Bilusic, Albert Craig Lockhart, Annie Beuve, Priyamvada Rai
Publikováno v:
bioRxiv
Castration-resistant prostate cancer (CRPC) is fatal and therapeutically under-served. We describe a novel CRPC-restraining role for the vasodilatory soluble guanylyl cyclase (sGC) pathway. We discovered that sGC subunits are dysregulated during CRPC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0180f12db1937cf0d191228ce78e16f6
https://doi.org/10.1101/2023.05.03.537252
https://doi.org/10.1101/2023.05.03.537252
Autor:
David M. Hyman, Bethany Pitcher, Todd Riehl, Eric J. Sherman, Gregory J. Riely, Eli L. Diamond, Jason Roszik, Funda Meric-Bernstam, José Baselga, Juergen Wolf, Noopur S. Raje, A. Craig Lockhart, Ian Chau, Jean-Yves Blay, Igor Puzanov, Vivek Subbiah
Supplementary figures 1 & 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::352b7e195351285e41e52d749735d71c
https://doi.org/10.1158/2159-8290.22535063
https://doi.org/10.1158/2159-8290.22535063
Autor:
David M. Hyman, Bethany Pitcher, Todd Riehl, Eric J. Sherman, Gregory J. Riely, Eli L. Diamond, Jason Roszik, Funda Meric-Bernstam, José Baselga, Juergen Wolf, Noopur S. Raje, A. Craig Lockhart, Ian Chau, Jean-Yves Blay, Igor Puzanov, Vivek Subbiah
BRAFV600 mutations occur in a wide range of tumor types, and RAF inhibition has become standard in several of these cancers. Despite this progress, BRAFV600 mutations have historically been considered a clear demonstration of tumor lineage context–
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b7a921d27c9d3f8082e6fbbe95a137e
https://doi.org/10.1158/2159-8290.c.6547751.v1
https://doi.org/10.1158/2159-8290.c.6547751.v1
Autor:
David M. Hyman, Bethany Pitcher, Todd Riehl, Eric J. Sherman, Gregory J. Riely, Eli L. Diamond, Jason Roszik, Funda Meric-Bernstam, José Baselga, Juergen Wolf, Noopur S. Raje, A. Craig Lockhart, Ian Chau, Jean-Yves Blay, Igor Puzanov, Vivek Subbiah
Supplementary Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::244aa43cad509723adfef3b31cee84c0
https://doi.org/10.1158/2159-8290.22535060.v1
https://doi.org/10.1158/2159-8290.22535060.v1
Autor:
David M. Hyman, Bethany Pitcher, Todd Riehl, Eric J. Sherman, Gregory J. Riely, Eli L. Diamond, Jason Roszik, Funda Meric-Bernstam, José Baselga, Juergen Wolf, Noopur S. Raje, A. Craig Lockhart, Ian Chau, Jean-Yves Blay, Igor Puzanov, Vivek Subbiah
Protocol appendix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c4e4a827720b71dca1ec2e6b3886f0
https://doi.org/10.1158/2159-8290.22535054
https://doi.org/10.1158/2159-8290.22535054
Autor:
Wael El-Rifai, A. Craig Lockhart, Abbes Belkhiri, Dunfa Peng, Lihong Wang, Zheng Chen, Shoumin Zhu
Purpose: We aimed to investigate the therapeutic efficacy of single agent and the combination of quinacrine and suberoylanilide hydroxamic acid (SAHA) in wt- and mut-p53 upper gastrointestinal cancer (UGC) cell models.Experimental Design: ATP-Glo, cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09f8703d6c0a5bce762c965f730aa032
https://doi.org/10.1158/1078-0432.c.6525938.v1
https://doi.org/10.1158/1078-0432.c.6525938.v1