Zobrazeno 1 - 10
of 408
pro vyhledávání: '"Craig L Slingluff,"'
Autor:
Walter C Olson, Max O Meneveau, Kevin T Lynch, Christine A Tran, Priya Katyal, Craig L Slingluff,
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 2 (2023)
Background Immune-mediated melanoma regression relies on melanoma-reactive T cells infiltrating tumor. Cancer vaccines increase circulating melanoma-reactive T cells, but little is known about vaccine-induced circulating lymphocytes (viCLs) homing to
Externí odkaz:
https://doaj.org/article/47178d74b5a14c51966fd54e06e8bc6a
Autor:
Kelly T Smith, Nikole Varhegyi, Nolan A Wages, Emily H Hall, Kathleen Haden, Craig L Slingluff, Jr., Lynn T Dengel, Anna Dickinson, Caroline Reed, Elizabeth M Gaughan, Varinder Kaur, Nadejda V Galeassi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
Background Peptide vaccines designed to stimulate melanoma-reactive CD4+ T cells can induce T cell and antibody (Ab) responses, associated with enhanced overall survival. We hypothesized that adding toll-like receptor 3 agonist polyICLC to an incompl
Externí odkaz:
https://doaj.org/article/0f1633d6e6534feb8dfa73c25184c8d5
Autor:
Mark E Smolkin, Gina R Petroni, Kimberly A Chianese-bullock, Kelly T Smith, Geoffrey Weiss, Nico Buettner, Mark Cobbold, Jeffrey Shabanowitz, Nikole Varhegyi, Elizabeth Gaughan, Victor H Engelhard, Rebecca C Obeng, Kara L Cummings, Angela L Ambakhutwala, Amanda Lulu, Paisley Myers, Keira E Mahoney, Emily H Hall, Kathleen Haden, Donald F Hunt, Craig L Slingluff, Jr
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Phosphorylated peptides presented by MHC molecules represent a new class of neoantigens expressed on cancer cells and recognized by CD8 T-cells. These peptides are promising targets for cancer immunotherapy. Previous work identified an HLA
Externí odkaz:
https://doaj.org/article/2f1ba13970c949eeb55d8d1382a456e4
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)
Water-in-oil emulsion incomplete Freund’s adjuvant (IFA) has been used as an adjuvant in preventive and therapeutic vaccines since its development. New generation, highly purified modulations of the adjuvant, Montanide incomplete seppic adjuvant (I
Externí odkaz:
https://doaj.org/article/b097e9a4d6bc48179b97981152b135d5
Autor:
Annie K. Kogler, Andrew M. Polemi, Surabhi Nair, Stanislaw Majewski, Lynn T. Dengel, Craig L. Slingluff, Brian Kross, S. J. Lee, J. E. McKisson, John McKisson, Andrew G. Weisenberger, Benjamin L. Welch, Thomas Wendler, Philipp Matthies, Joerg Traub, Michael Witt, Mark B. Williams
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Background Assessment of lymphatic status via sentinel lymph node (SLN) biopsy is an integral and crucial part of melanoma surgical oncology. The most common technique for sentinel node mapping is preoperative planar scintigraphy of an injec
Externí odkaz:
https://doaj.org/article/3e0f721acbfe4a46a1e82e9ab414f315
Autor:
Puja Arora, Laura Talamo, Patrick Dillon, Ryan D. Gentzler, Trish Millard, Michael Salerno, Craig L. Slingluff, Elizabeth M. Gaughan
Publikováno v:
Cardio-Oncology, Vol 6, Iss 1, Pp 1-11 (2020)
Abstract Background Immune checkpoint inhibition is part of standard systemic management for many advanced malignancies. Toxicities from this treatment approach are unpredictable, though usually reversible with management per established guidelines.
Externí odkaz:
https://doaj.org/article/d2c780cf67664090a1984d81ad26ed4f
Autor:
Nicole L. Edmonds, Sarah E. Flores, Adela Mahmutovic, Samuel J. Young, Ileana S. Mauldin, Craig L. Slingluff
Publikováno v:
Melanoma research. 32(6)
This study was designed to screen for preliminary evidence of predictive markers of melanoma response to PD-1 blockade. We hypothesized that the following immune markers would be positive predictors of response: increased densities of CD103 + CD8 + T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de90b13bdfb13f0a9f8b9148d9f4e8e
https://pubmed.ncbi.nlm.nih.gov/36169985
https://pubmed.ncbi.nlm.nih.gov/36169985
Autor:
Marit M. Melssen, Gina R. Petroni, Kimberly A. Chianese-Bullock, Nolan A. Wages, William W. Grosh, Nikole Varhegyi, Mark E. Smolkin, Kelly T. Smith, Nadejda V. Galeassi, Donna H. Deacon, Elizabeth M. Gaughan, Craig L. Slingluff
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Background Cancer vaccines require adjuvants to induce effective immune responses; however, there is no consensus on optimal adjuvants. We hypothesized that toll-like receptor (TLR)3 agonist polyICLC or TLR4 agonist lipopolysaccharide (LPS),
Externí odkaz:
https://doaj.org/article/a8026c4ba7c5475c8be9506d9626cbab
Autor:
Joshua M. Judge, Kosta Popovic, Gina R. Petroni, Brian Kross, John McKisson, Jack McKisson, Andrew G. Weisenberger, Alexander Stolin, Stan Majewski, Patrice Rehm, Craig L. Slingluff, Mark B. Williams, Lynn T. Dengel
Publikováno v:
Journal of Surgical Research. 285:176-186
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d11fc689e5c3e2e58f505241cfa7907
https://doi.org/10.1016/j.jss.2022.12.013
https://doi.org/10.1016/j.jss.2022.12.013
Publikováno v:
OncoImmunology, Vol 8, Iss 12 (2019)
Background: We have identified, in melanomas, a set of genes encoding proteins that mediate mechanical barrier function in normal skin (barrier molecule genes, BMGs) and whose overexpression is associated with decreased immune signatures and shorter
Externí odkaz:
https://doaj.org/article/7cf98e6ff74946888f5c4f92f62188eb