Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Craig J. van Dolleweerd"'
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229877 (2020)
Rhabdoviruses are enveloped negative-sense RNA viruses that have numerous biotechnological applications. However, recovering plant rhabdoviruses from cDNA remains difficult due to technical difficulties such as the need for concurrent in planta expre
Externí odkaz:
https://doaj.org/article/490ccf5a082c4302b73563577e37ef2c
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229877 (2020)
PLoS ONE
PLoS ONE
Rhabdoviruses are enveloped negative-sense RNA viruses that have numerous biotechnological applications. However, recovering plant rhabdoviruses from cDNA remains difficult due to technical difficulties such as the need for concurrent in planta expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92b113eeea84240bbb1793e8ab44b14f
https://doaj.org/article/490ccf5a082c4302b73563577e37ef2c
https://doaj.org/article/490ccf5a082c4302b73563577e37ef2c
Autor:
Rajko Reljic, Mathew J. Paul, Gina R. Webster, Sven Hofmann, Thais Guerra, Szymon Stelter, Gil R. Diogo, Audrey Y.-H. Teh, Alastair Copland, Peter Hart, Julian K.-C. Ma, Craig J. van Dolleweerd, Mi-Young Kim
Publikováno v:
Plant Biotechnology Journal
Summary In this study, a strategy based on polymeric immunoglobulin G scaffolds (PIGS) was used to produce a vaccine candidate for Mycobacterium tuberculosis. A genetic fusion construct comprising genes encoding the mycobacterial Ag85B antigen, an im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b21da45ccc43a8fd718c85b3f6a8766
https://doi.org/10.1111/pbi.12932
https://doi.org/10.1111/pbi.12932
Autor:
Paul P. Gardner, Augustine Chen, Craig J. van Dolleweerd, Chun Shen Lim, Daniela M. Remus, Bikash K. Bhandari
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 10, p e1009461 (2021)
PLoS Computational Biology
PLoS Computational Biology
Recombinant protein production is a key process in generating proteins of interest in the pharmaceutical industry and biomedical research. However, about 50% of recombinant proteins fail to be expressed in a variety of host cells. Here we show that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b4e4f26b40648f03e797c5a7b104256
https://doi.org/10.1371/journal.pcbi.1009461
https://doi.org/10.1371/journal.pcbi.1009461
Autor:
Gil R. Diogo, Szymon Stelter, Pascal M. W. Drake, Peter Hart, Matthew J. Paul, Alastair Copland, Craig J. van Dolleweerd, Rajko Reljic, Derek C. Macallan, Adam Sparrow
Publikováno v:
Cytokine
IL-4 is a pleiotropic cytokine that is highly Th2 polarizing. The ratio of IL-4 and its splice variant IL-4Δ2 observed in human health and disease suggests a role for both isoforms. In the present study, the biological function of murine IL-4Δ2 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2375c29163948aa222c198ab9874e559
https://doi.org/10.1016/j.cyto.2017.09.007
https://doi.org/10.1016/j.cyto.2017.09.007
Autor:
Alastair Copland, Emily Julik, Craig J. van Dolleweerd, Rajko Reljic, Matthew J. Paul, Mi-Young Kim, Jorge Reyes-del Valle, Ivonne Ceballos-Olvera, Julian K.-C. Ma, Gina R. Webster, Sven Hofmann, Moon-Sik Yang, Yong-Suk Jang
Publikováno v:
Plant Biotechnology Journal
Summary In order to enhance vaccine uptake by the immune cells in vivo, molecular engineering approach was employed to construct a polymeric immunoglobulin G scaffold (PIGS) that incorporates multiple copies of an antigen and targets the Fc gamma rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a90c103cc1421c94fdcc45048c819df
https://doi.org/10.1111/pbi.12741
https://doi.org/10.1111/pbi.12741
Autor:
Daniela M. Remus, Paul P. Gardner, Bikash K. Bhandari, Chun Shen Lim, Craig J. van Dolleweerd, Augustine Chen
Recombinant protein production is a widely used technique, yet half of these experiments fail at the expression phase. Failures are expected for 9difficult-to-express9 proteins, but for others, codon bias and mRNA folding have been proposed explanati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::371b0c2de8ea1a4110dacb1870dd1073
https://doi.org/10.1101/726752
https://doi.org/10.1101/726752
Autor:
Rudranuj Bundela, Kyle C. Van de Bittner, Matthew J. Nicholson, Emily J. Parker, Sarah A. Kessans, Craig J. van Dolleweerd, Leyla Y. Bustamante, Barry Scott
Publikováno v:
ACS synthetic biology. 7(4)
A modular and hierarchical DNA assembly platform for synthetic biology based on Golden Gate (Type IIS restriction enzyme) cloning is described. This enabling technology, termed MIDAS (for Modular Idempotent DNA Assembly System), can be used to precis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2304cef8673a59362b6a9a82de072fc
https://pubmed.ncbi.nlm.nih.gov/29620866
https://pubmed.ncbi.nlm.nih.gov/29620866
Autor:
Sarah A. Kessans, Barry Scott, Kyle C. Van de Bittner, Arvina Ram, Leyla Y. Bustamante, Craig J. van Dolleweerd, Matthew J. Nicholson, Emily J. Parker
Publikováno v:
Journal of the American Chemical Society. 140(2)
Nodulisporic acids comprise a group of valuable indole diterpenes that exhibit potent insecticidal activities. We report the identification of a gene cluster in the genome of the filamentous fungus Hypoxylon pulicicidum (Nodulisporium sp.) that conta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d7674a6cac91b48ef0a53893641874
https://pubmed.ncbi.nlm.nih.gov/29283570
https://pubmed.ncbi.nlm.nih.gov/29283570
Autor:
Angela Bartolf, Susan Baden, Markus Windwarder, Julian K.-C. Ma, Rajko Reljic, Elsa Arcalis, Matthew J. Paul, Eva Stoger, Pascal M. W. Drake, Catherine Cosgrove, Craig J. van Dolleweerd, Martin Pabst, Katja Klein, Friedrich Altmann
Publikováno v:
mAbs. 6:1585-1597
Recombinant Secretory IgA (SIgA) complexes have the potential to improve antibody-based passive immunotherapeutic approaches to combat many mucosal pathogens. In this report, we describe the expression, purification and characterization of a human SI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7893bf61b71c3e419f1b9042e61fd39f
https://doi.org/10.4161/mabs.36336
https://doi.org/10.4161/mabs.36336