Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Craig J. Reist"'
Autor:
Renato D. Lopes, Robert A. Harrington, Brooke Alhanti, Christopher B. Granger, Sunil V. Rao, Kenneth W. Mahaffey, Akash Goyal, W. Schuyler Jones, Matthew T. Roe, Lisa G. Berdan, Manesh R. Patel, Tyrus Rorick, Jennifer B. Green, Craig J. Reist, Karen L. Hannan, Tony Schibler, Michael A. Blazing, Robert M. Califf, Eric D. Peterson, Adrian F. Hernandez, John H. Alexander
Publikováno v:
JAMA Network Open. 4:e2117963
Randomized clinical trials (RCTs) are critical in advancing patient care, yet conducting such large-scale trials requires tremendous resources and coordination. Clinical site start-up performance metrics can provide insight into opportunities for imp
Autor:
Daniel Isaza, Craig J. Reist, KyungAh Im, Jennifer A. White, Andrew M. Tershakovec, Robert P. Giugliano, Eugene Braunwald, Michael A. Blazing, Christopher P. Cannon, Mikael Dellborg, Erin A. Bohula, Sabina A. Murphy, Uma Kher, Yuliya Lokhnygina, Jose Lopez-Sendon
Publikováno v:
Journal of the American College of Cardiology. 67(4):353-361
Background Intensive low-density lipoprotein cholesterol therapy with ezetimibe/simvastatin in IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial) significantly reduced the first primary endpoint (PEP) in patients post-a
Autor:
Kenneth W. Mahaffey, Craig J. Reist, W. Schuyler Jones, Jeffrey S. Berger, Marcus Millegård, William R. Hiatt, Lars Norgren, Brian G. Katona, F. Gerry R. Fowkes, Iris Baumgartner, Peter Held, Manesh R. Patel, Juuso I. Blomster, Gretchen M. Heizer
Publikováno v:
Berger, Jeffrey S; Katona, Brian G; Jones, W Schuyler; Patel, Manesh R; Norgren, Lars; Baumgartner, Iris; Blomster, Juuso; Mahaffey, Kenneth W; Held, Peter; Millegård, Marcus; Heizer, Gretchen; Reist, Craig; Fowkes, F Gerry; Hiatt, William R (2016). Design and rationale for the Effects of Ticagrelor and Clopidogrel in Patients with Peripheral Artery Disease (EUCLID) trial. American Heart Journal, 175, pp. 86-93. Elsevier 10.1016/j.ahj.2016.01.018
Background Despite overwhelming data demonstrating the efficacy of antiplatelet therapy in heart disease and stroke, data in peripheral artery disease (PAD) are less compelling. Aspirin has modest evidence supporting a reduction in cardiovascular eve
Autor:
Peter Held, Craig J. Reist, F. Gerry R. Fowkes, Beth L. Abramson, William R. Hiatt, Manesh R. Patel, Kenneth W. Mahaffey, W. Schuyler Jones, Marcus Millegård, Renato D. Lopes, Lars Norgren, Iris Baumgartner, Frank W. Rockhold, Juuso I. Blomster, Jeffrey S. Berger, Gretchen M. Heizer, Brian G. Katona
Publikováno v:
Vascular medicine (London, England). 23(6)
Patients with peripheral artery disease (PAD) are at heightened risk of cardiovascular morbidity and mortality. We sought to evaluate the risk of concomitant coronary artery disease (CAD) in patients with symptomatic PAD versus PAD without diagnosed
Autor:
Craig J. Reist, Matthew T. Roe, Christian W. Hamm, Justin A. Ezekowitz, Kenneth W. Mahaffey, Christopher B. Granger, Sean van Diepen, Judith S. Hochman, David J. Moliterno, Stefan James, Pierre Theroux, Amanda Stebbins, Vic Hasselblad, Paul W. Armstrong, L. Kristin Newby, Renato D. Lopes, Franz-Josef Neumann
Publikováno v:
International Journal of Cardiology. 168:2127-2133
Background: Plaque rupture, acute ischemia, and necrosis in acute coronary syndromes are accompanied by concurrent pro-and anti-inflammatory cascades. Whether STEMI clinical prediction models can b ...
Autor:
Eugene Braunwald, Christie M. Ballantyne, Thomas Musliner, Christopher P. Cannon, Jennifer White, Yuliya Lokhnygina, Craig J. Reist, Basil S. Lewis, Andrew M. Tershakovec, Andrew Tonkin, Amy McCagg, Robert P. Giugliano, Michael A. Blazing, James A. de Lemos
Publikováno v:
American heart journal. 182
Background We aimed to determine the efficacy and safety of adding ezetimibe (Ez) to simvastatin (S) in a post–acute coronary syndrome (ACS) population in a prespecified on-treatment analysis. Methods We evaluated 17,706 post-ACS patients from the
Autor:
Kenneth W. Mahaffey, Neal S. Kleiman, James T. Willerson, Craig J. Reist, Grazyna Czernuszewicz, Ali J. Marian, Gabriella Rodriguez, Amit Manhas, Ahmad Alhariri, Karen S. Pieper, Aijing Z. Starr
Publikováno v:
European Journal of Clinical Investigation. 41:1299-1309
Eur J Clin Invest 2011; 41 (12): 1299–1309 Abstract Background Vitamin D is implicated in various biological functions ranging from cellular proliferation to immunity. Vitamin D deficiency is associated with an increased risk of several diseases in
Autor:
Hongqiu Yang, Mark I. Furman, Craig J. Reist, Kenneth W. Mahaffey, Richard C. Becker, Neal S. Kleiman, John L. Petersen, A. Michael Lincoff, Ali J. Marian, Stanley L. Hazen
Publikováno v:
Journal of Thrombosis and Thrombolysis. 31:146-153
Heparin compounds, to include fractionated and unfractionated preparations, exert both antithrombotic and antiinflammatory effects through combined inhibition of factor Xa and thrombin. The contribution of modulated platelet activity in vivo is less
Autor:
Sema Güneri, Shaun G. Goodman, Karen S. Pieper, Kenneth W. Mahaffey, Jason P. Linefsky, Robert M. Califf, L. Kristin Newby, Min Lin, Craig J. Reist, Matthew T. Roe, James J. Ferguson, Robert A. Harrington, Lisa G. Berdan, Elliott M. Antman, John K. French
Publikováno v:
The American Journal of Cardiology. 104:1330-1335
The effect of nonstandardized creatine kinase (CK)-MB assays on the assessment of myocardial infarction (MI) end points in multicenter international trials has not been evaluated. We compared the site-reported and corresponding core laboratory CK-MB
Autor:
Kenneth W, Mahaffey, Craig J, Reist, Yuling, Fu, Sorin J, Brener, Pierre, Theroux, Manesh R, Patel, Amanda, Stebbins, Cynthia M, Westerhout, Thomas G, Todaro, Peter X, Adams, Christopher B, Granger, Paul W, Armstrong, Thorsten, Dill
Publikováno v:
Contemporary Clinical Trials. 29:887-895
The APEX library was a coordinated and integrated set of ancillary analyses and substudies that were a part of the large APEX-AMI trial. The library included electrocardiogram, angiographic, blood biomarker, genetics, and MRI components. Operationall