Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Craig J. Dowling"'
High-throughput screening and rapid inhibitor triage using an infectious chimeric Hepatitis C virus.
Autor:
Michael J Wichroski, Jie Fang, Betsy J Eggers, Ronald E Rose, Charles E Mazzucco, Kevin A Pokornowski, Carl J Baldick, Monique N Anthony, Craig J Dowling, Lauren E Barber, John E Leet, Brett R Beno, Samuel W Gerritz, Michele L Agler, Mark I Cockett, Daniel J Tenney
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42609 (2012)
The recent development of a Hepatitis C virus (HCV) infectious virus cell culture model system has facilitated the development of whole-virus screening assays which can be used to interrogate the entire virus life cycle. Here, we describe the develop
Externí odkaz:
https://doaj.org/article/c696c60727114ef3a6359c336e98b64f
Autor:
Martyn Banks, Ashley M. Hine, Caitlin E. Scott, Jefferson Chin, Litao Zhang, Mike Power, Yu-Hsien Liao, Lisa M. Ogawa, Samuel Gerritz, Edward J. Hunnicutt, Craig J. Dowling, Debra A. Kendall, Neil T. Burford, Andrew Alt, Victoria L. Emerick
Publikováno v:
SLAS Discovery. 23:375-383
The endocannabinoid system (ECS) plays a diverse role in human physiology ranging from the regulation of mood and appetite to immune modulation and the response to pain. Drug development that targets the cannabinoid receptors (CB(1) and CB(2)) has be
Publikováno v:
Journal of biomolecular screening. 20(5)
High-performance liquid chromatography (HPLC) biogram methodology is a powerful pharmaceutical screening hit confirmation strategy that couples analytical HPLC data with functional bioassay data. It is used primarily for screening hit chemical valida
Autor:
Ronald E. Rose, Craig J. Dowling, Mark I. Cockett, Michael Wichroski, Lauren E. Barber, Daniel J. Tenney, Michele Agler, Samuel Gerritz, Brett R. Beno, Betsy J. Eggers, Charles E. Mazzucco, John E. Leet, Carl J. Baldick, Kevin A. Pokornowski, Monique Anthony, Jie Fang
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 8, p e42609 (2012)
PLoS ONE, Vol 7, Iss 8, p e42609 (2012)
The recent development of a Hepatitis C virus (HCV) infectious virus cell culture model system has facilitated the development of whole-virus screening assays which can be used to interrogate the entire virus life cycle. Here, we describe the develop