Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Craig J. Beisel"'
Publikováno v:
PLoS Genetics, Vol 7, Iss 6, p e1002075 (2011)
Epistatic interactions between genes and individual mutations are major determinants of the evolutionary properties of genetic systems and have therefore been well documented, but few quantitative data exist on epistatic interactions between benefici
Externí odkaz:
https://doaj.org/article/c7c4edfa297b44fd9cb13c556f9e7e77
Publikováno v:
Genetics. 180:1627-1643
Recent theoretical studies of the adaptation of DNA sequences assume that the distribution of fitness effects among new beneficial mutations is exponential. This has been justified by using extreme value theory and, in particular, by assuming that th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03f8daca1aea938890fe896791e41e18
https://doi.org/10.1534/genetics.108.088716
https://doi.org/10.1534/genetics.108.088716
Publikováno v:
Genetics. 176:2441-2449
In modeling evolutionary genetics, it is often assumed that mutational effects are assigned according to a continuous probability distribution, and multiple distributions have been used with varying degrees of justification. For mutations with benefi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9549e9675171c25ccabc0da7703bc48
https://doi.org/10.1534/genetics.106.068585
https://doi.org/10.1534/genetics.106.068585
Publikováno v:
Journal of Theoretical Biology. 243:114-120
We examine properties of adaptive walks on uncorrelated (i.e. random) fitness landscapes starting from moderately fit genotypes under strong selection weak mutation. As an extension of Orr’s model for a single step in an adaptive walk under these c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97c877e5eb954b1c292433438987e2e9
https://doi.org/10.1016/j.jtbi.2006.06.008
https://doi.org/10.1016/j.jtbi.2006.06.008
Autor:
S. Brian Caudle, Craig R. Miller, Darin R. Rokyta, Paul Joyce, Craig J. Beisel, Holly A. Wichman
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 7, Iss 6, p e1002075 (2011)
PLoS Genetics, Vol 7, Iss 6, p e1002075 (2011)
Epistatic interactions between genes and individual mutations are major determinants of the evolutionary properties of genetic systems and have therefore been well documented, but few quantitative data exist on epistatic interactions between benefici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::629283106416e51b35ebca9a6c4c240b
https://pubmed.ncbi.nlm.nih.gov/21655079
https://pubmed.ncbi.nlm.nih.gov/21655079
Autor:
Holly A. Wichman, Christina L. Burch, Martin T. Ferris, Craig J. Beisel, Darin R. Rokyta, Paul Joyce
The distribution of fitness effects for beneficial mutations is of paramount importance in determining the outcome of adaptation. It is generally assumed that fitness effects of beneficial mutations follow an exponential distribution, for example, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc0f9d5b25dce58d54642ddf3b8a1502
https://europepmc.org/articles/PMC2600421/
https://europepmc.org/articles/PMC2600421/
