Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Craig Hyde"'
Autor:
Stanley Cohen, Jean S. Beebe, Vishala Chindalore, Shunjie Guan, Mina Hassan-Zahraee, Madhurima Saxena, Li Xi, Craig Hyde, Sarita Koride, Robert Levin, Shannon Lubaczewski, Mikhail Salganik, Abigail Sloan, Erin Stevens, Elena Peeva, Michael S. Vincent, David A. Martin, Myron Chu
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-18 (2024)
Abstract Background The objective of this study was to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of PF‑06835375, a potent selective afucosyl immunoglobulin G1 antibody targeting C-X-C chemokine receptor type 5 (CXCR5
Externí odkaz:
https://doaj.org/article/de4e6e08230342d8a8ccd262c81c4143
Autor:
Kodihalli C. Ravindra, Vishal S. Vaidya, Zhenyu Wang, Joel D. Federspiel, Richard Virgen-Slane, Robert A. Everley, Jane I. Grove, Camilla Stephens, Mireia F. Ocana, Mercedes Robles-Díaz, M. Isabel Lucena, Raul J. Andrade, Edmond Atallah, Alexander L. Gerbes, Sabine Weber, Helena Cortez-Pinto, Andrew J. Fowell, Hyder Hussaini, Einar S. Bjornsson, Janisha Patel, Guido Stirnimann, Sumita Verma, Ahmed M. Elsharkawy, William J. H. Griffiths, Craig Hyde, James W. Dear, Guruprasad P. Aithal, Shashi K. Ramaiah
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Diagnosis of rare, unpredictable, drug-induced liver injury (DILI) is a significant challenge for patients, clinicians, and drug development. Here, the authors discover, evaluate, and validate potential blood biomarkers to diagnose DILI and distingui
Externí odkaz:
https://doaj.org/article/ec3315a517864777bd5bdde19a8b8aa2
Autor:
Li Xi, Sandra Garcet, Zhan Ye, Kenneth Hung, Mina Hassan-Zahraee, Elizabeth Kieras, James G. Krueger, Craig Hyde, Elena Peeva
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Despite multiple efficacious therapies in common between psoriasis (PS) and Ulcerative Colitis (UC), mechanisms underlying their common pathophysiology remain largely unclear. Here we sought to establish a link by evaluating expression diffe
Externí odkaz:
https://doaj.org/article/f2776b8b8cd2456abd8d222a0dbf6c07
Autor:
Eric B. Fauman, Craig Hyde
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-11 (2022)
Abstract Background A genome-wide association study (GWAS) correlates variation in the genotype with variation in the phenotype across a cohort, but the causal gene mediating that impact is often unclear. When the phenotype is protein abundance, a re
Externí odkaz:
https://doaj.org/article/d5e248c176ab4b749b3555cd3b483d36
Autor:
Zoltan Szekanecz, Zhenyu Wang, Jeffrey I Weitz, Christina Charles-Schoeman, Ivana Vranic, David A Martin, Craig Hyde, Burak Sahin, Sara A Paciga
Publikováno v:
RMD Open, Vol 8, Iss 2 (2022)
Objective In the ORAL (Oral Rheumatoid Arthritis triaL) Surveillance study of patients with rheumatoid arthritis aged ≥50 years with ≥1 additional cardiovascular risk factor, incidence of pulmonary embolism was higher with tofacitinib 10 mg two t
Externí odkaz:
https://doaj.org/article/ac8819ddd6204ea79823fc674a0a6816
Autor:
Christopher D. Whelan, Niklas Mattsson, Michael W. Nagle, Swetha Vijayaraghavan, Craig Hyde, Shorena Janelidze, Erik Stomrud, Julie Lee, Lori Fitz, Tarek A. Samad, Gayathri Ramaswamy, Richard A. Margolin, Anders Malarstig, Oskar Hansson
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-14 (2019)
Abstract To date, the development of disease-modifying therapies for Alzheimer’s disease (AD) has largely focused on the removal of amyloid beta Aβ fragments from the CNS. Proteomic profiling of patient fluids may help identify novel therapeutic t
Externí odkaz:
https://doaj.org/article/d2b5bbd9197e4ce8a2ccfd4b15b135e3
Autor:
Harshal A. Deshmukh, Helen M. Colhoun, Toby Johnson, Paul M. McKeigue, D. John Betteridge, Paul N. Durrington, John H. Fuller, Shona Livingstone, Valentine Charlton-Menys, Andrew Neil, Neil Poulter, Peter Sever, Denis C. Shields, Alice V. Stanton, Aurobindo Chatterjee, Craig Hyde, Roberto A. Calle, David A. DeMicco, Stella Trompet, Iris Postmus, Ian Ford, J. Wouter Jukema, Mark Caulfield, Graham A. Hitman
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 5, Pp 1000-1011 (2012)
We carried out a genome-wide association study (GWAS) of LDL-c response to statin using data from participants in the Collaborative Atorvastatin Diabetes Study (CARDS; n = 1,156), the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT; n = 895), and th
Externí odkaz:
https://doaj.org/article/0e30b62ae4ad49fe9ad70c633f99fac3
Autor:
Holly Soares, Mary Lynn Baniecki, Rhonda Cardin, Heidi Leister-Tebbe, Yuao Zhu, Shunjie Guan, Craig Hyde, Wen He, Zhenyu Wang, Li Hao, B. Scott Perrin, Weihang Bao, Phylinda Chan, Bharat Damle, Sandeep Menon, Jennifer Hammond, Annaliesa Anderson
Nirmatrelvir-ritonavir was developed for the treatment of COVID-19 and has shown efficacy in a Phase 2/3 study of high risk patients (EPIC-HR1). Monitoring for the emergence of viral resistance and recurrence of symptoms is a critical component of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b1f8ec06bf8c5c4f1e60546fee9d66
https://doi.org/10.21203/rs.3.rs-1720472/v2
https://doi.org/10.21203/rs.3.rs-1720472/v2
BackgroundAtopic Dermatitis (AD) is a persistent inflammatory disease of the skin to which a few novel treatment options have recently become available. Multiple published datasets, from RNA sequencing (RNA-seq) and microarray experiments performed o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71e4ba29eb5f7c54ca23241386af6cc4
https://doi.org/10.1101/2022.05.24.493180
https://doi.org/10.1101/2022.05.24.493180
Autor:
Jeffrey I Weitz, Zoltán Szekanecz, Christina Charles-Schoeman, Ivana Vranic, Burak Sahin, Sara A Paciga, Zhenyu Wang, Craig Hyde, David A Martin
Publikováno v:
RMD Open. 8:e002571
ObjectiveIn the ORAL (Oral Rheumatoid Arthritis triaL) Surveillance study of patients with rheumatoid arthritis aged ≥50 years with ≥1 additional cardiovascular risk factor, incidence of pulmonary embolism was higher with tofacitinib 10 mg two ti