Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Craig Hemann"'
Autor:
Xiaoping Liu, Mohamed A. El-Mahdy, James Boslett, Saradhadevi Varadharaj, Craig Hemann, Tamer M. Abdelghany, Raed S. Ismail, Sean C. Little, Danlei Zhou, Le Thi Thanh Thuy, Norifumi Kawada, Jay L. Zweier
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
The gaseous signalling molecule nitric oxide regulates vascular tone. Here, the authors show that nitric oxide is degraded by the enzyme cytoglobin in the vascular wall, and that mice lacking cytoglobin have reduced blood pressure and are less sensit
Externí odkaz:
https://doaj.org/article/7c48b88ebe1f45628a4d604983c1bc11
Autor:
Jaideep Banerjee, Piya Das Ghatak, Sashwati Roy, Savita Khanna, Craig Hemann, Binbin Deng, Amitava Das, Jay L Zweier, Daniel Wozniak, Chandan K Sen
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119531 (2015)
Pseudomonas aeruginosa biofilm is commonly associated with chronic wound infection. A FDA approved wireless electroceutical dressing (WED), which in the presence of conductive wound exudate gets activated to generate electric field (0.3-0.9V), was in
Externí odkaz:
https://doaj.org/article/ab25bc5602c74c42a86c704f969a5492
Publikováno v:
The FASEB Journal. 36
Autor:
Jay L. Zweier, Craig Hemann, Tapan Kundu, Mohamed G. Ewees, Sahar A. Khaleel, Alexandre Samouilov, Govindasamy Ilangovan, Mohamed A. El-Mahdy
Publikováno v:
Proc Natl Acad Sci U S A
Cytoglobin (Cygb) was discovered as a novel type of globin that is expressed in mammals; however, its functions remain uncertain. While Cygb protects against oxidant stress, the basis for this is unclear, and the effect of Cygb on superoxide metaboli
Autor:
Mohamed A. El-Mahdy, Jay L. Zweier, Craig Hemann, Govindasamy Ilangovan, Sahar A. Khaleel, Tapan Kumar Kundu
Publikováno v:
The FASEB Journal. 35
Autor:
Jay L. Zweier, Mohamed A. El-Mahdy, Tapan Kumar Kundu, Sahar A. Khaleel, Craig Hemann, Govindasamy Ilangovan
Publikováno v:
The Journal of Biological Chemistry
In smooth muscle, cytoglobin (Cygb) functions as a potent nitric oxide (NO) dioxygenase and regulates NO metabolism and vascular tone. Major questions remain regarding which cellular reducing systems regulate Cygb-mediated NO metabolism. To better de
Autor:
Shahira Nofal, Osama A. Badary, Yasmin A. Alzarie, Mohamed A. El-Mahdy, Jay L. Zweier, Craig Hemann
Publikováno v:
Free Radic Biol Med
While radiotherapy is a widely used treatment for many types of human cancer, problems of radio-resistance and side effects remain. Side effects induced by ionizing radiation (IR) arise primarily from its propensity to trigger inflammation and oxidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60649efe61dae5d44f2326628978ff0d
https://europepmc.org/articles/PMC7704930/
https://europepmc.org/articles/PMC7704930/
Autor:
Craig Hemann, Elsayed M Mahgoup, Tamer M. Abdelghany, Mahmoud S Eid, Mohamed G Ewees, Mahmoud T Shalaan, Mohamed A. El-Mahdy, Yasmin A. Alzarie, Jay L. Zweier
Publikováno v:
Am J Physiol Heart Circ Physiol
Although there is a strong association between cigarette smoking exposure (CSE) and vascular endothelial dysfunction (VED), the underlying mechanisms by which CSE triggers VED remain unclear. Therefore, studies were performed to define these mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::418380cf2cd458fb855efb4418b95ea5
https://europepmc.org/articles/PMC7474439/
https://europepmc.org/articles/PMC7474439/
Publikováno v:
FEBS Open Bio
Cytoglobin (Cygb), like other members of the globin family, is a nitric oxide (NO) dioxygenase, metabolizing NO in an oxygen (O2)‐dependent manner. We examined the effect of modification of cysteine sulfhydryl groups of Cygb on its O2 binding and N
Autor:
Danlei Zhou, Sean C. Little, Jay L. Zweier, Craig Hemann, Norifumi Kawada, James Boslett, Mohamed A. El-Mahdy, Raed S. Ismail, Xiaoping Liu, Saradhadevi Varadharaj, Le Thi Thanh Thuy, Tamer M. Abdelghany
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications
Nature Communications
The identity of the specific nitric oxide dioxygenase (NOD) that serves as the main in vivo regulator of O2-dependent NO degradation in smooth muscle remains elusive. Cytoglobin (Cygb) is a recently discovered globin expressed in fibroblasts and smoo