Výsledky vyhledávání - "Craig G. Hall"

Splice variant in TCRzeta links T cell receptor signaling to a G-protein-related signaling pathway

Autor: Jeffrey F. Goldsmith, T. Prescott Atkinson, Craig G Hall, Perry M. Kirkham

Publikováno v: Biochemical and biophysical research communications. 310(3)

The T cell receptor zeta chain is required for efficient receptor expression and contributes to T cell receptor-mediated activation of ZAP-70 and PLC-gamma1 as well as other signaling functions. A splice variant of zeta has been described which conta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55225a6301fc2d8a02fd6d0f49af9afd
https://pubmed.ncbi.nlm.nih.gov/14550268

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Identification of an alternatively spliced isoform of the fyn tyrosine kinase

Autor: Jeffrey F. Goldsmith, T. Prescott Atkinson, Craig G Hall

Publikováno v: Biochemical and biophysical research communications. 298(4)

Two isoforms of the src-family tyrosine kinase p59fyn have been shown to arise through alternative splicing of exon 7 of the fyn gene. These isoforms have been designated fynT, expressed in hematopoietic cells, and fynB, expressed in the brain. Here,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b6db31f0713565d47fef3116938a178
https://pubmed.ncbi.nlm.nih.gov/12408980

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Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency

Autor: Richard M. Siegel, Hyung J. Chun, Craig G Hall, Jin Wang, Michael J. Lenardo, T. Prescott Atkinson, Janet K. Dale, Christina K. Speirs, Sharon E. Straus, Suzanne Skoda-Smith, Jennifer M. Puck, Manzoor Ahmad, Joie Davis, Lixin Zheng

Publikováno v: Nature. 419(6905)

Apoptosis is a form of programmed cell death that is controlled by aspartate-specific cysteine proteases called caspases. In the immune system, apoptosis counters the proliferation of lymphocytes to achieve a homeostatic balance, which allows potent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390dc7fe6e65b7f48444288446a7d5bf
https://pubmed.ncbi.nlm.nih.gov/12352964

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A chronic 'postinfectious' fatigue syndrome associated with benign lymphoproliferation, B-cell proliferation, and active replication of human herpesvirus-6

Autor: Lee M. Nadler, John L. Sullivan, Jerome Ritz, Dharam V. Ablashi, David S. Weinberg, N. Balachandran, Craig G. Hall, Arnold S. Freedman, Carl Saxinger, Anthony L. Komaroff, Dedra Buchwald, Rhoda Ashley, Michael A. Caligiuri

Publikováno v: Journal of clinical immunology. 10(6)

A 17-year-old, previously healthy woman developed an acute "mononucleosis-like" illness with an associated "atypical" pneumonitis, followed by years of debilitating chronic fatigue, fevers, a 10-kg weight loss, night sweats, and neurocognitive sympto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894e61ab08fa9178cfc85433c4071e8d
https://pubmed.ncbi.nlm.nih.gov/1964694

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Reversible self-association of a human myeloma protein. Thermodynamics and relevance to viscosity effects and solubility

Autor: Craig G. Hall, George N. Abraham

Publikováno v: Biochemistry. 23:5123-5129

Monoclonal IgG paraproteins associated with multiple myeloma, Felty's syndrome, and idiopathic cryoglobulinemia frequently produce disease due to a tendency to self-associate in vivo. The insolubility and viscosity effects of these proteins are of sp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbf8d96ceae42ffde36a91d511bd3de2
https://doi.org/10.1021/bi00317a007

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Size, shape, and hydration of a self-associating human IgG myeloma protein: axial asymmetry as a contributing factor in serum hyperviscosity

Autor: George N. Abraham, Craig G. Hall

Publikováno v: Archives of biochemistry and biophysics. 233(2)

Studies of sedimentation, diffusion, viscosity, and buoyant density have been carried out on a human IgG1-lambda myeloma protein (IgG-MIT) isolated from the serum of a patient with multiple myeloma and the hyperviscosity syndrome. In comparison with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62997f6bbb16f985491f44c7c75b44bd
https://pubmed.ncbi.nlm.nih.gov/6486791

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