Zobrazeno 1 - 10
of 253
pro vyhledávání: '"Craig F. Ferris"'
Autor:
Lila Harris-Blum, Zachary Smith, Richard J. Ortiz, Deepti Athreya, Arnold Chang, Praveen P. Kulkarni, Craig F. Ferris
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract LSD is a hallucinogen with complex neurobiological and behavioral effects. Underlying these effects are changes in brain neuroplasticity. This is the first study to follow the developmental changes in brain structure and function following L
Externí odkaz:
https://doaj.org/article/e5e2dc4fc1124717a84df8062847a3b3
Autor:
Preeti K. Sathe, Gargi R. Ramdasi, Kaylie Giammatteo, Harvens Beauzile, Shuyue Wang, Heng Zhang, Praveen Kulkarni, Raymond G. Booth, Craig F. Ferris
Publikováno v:
Pharmacology Research & Perspectives, Vol 11, Iss 5, Pp n/a-n/a (2023)
Abstract A novel serotonin ligand (−)‐MBP was developed for the treatment of schizophrenia that has 5‐HT2A/2B antagonist activity together with 5‐HT2C agonist activity. The multi‐functional activity of this novel drug candidate was characte
Externí odkaz:
https://doaj.org/article/111258ebd5264bafa71dab06a81a5a07
Autor:
Joshua S. Danoff, Emma A. Page, Allison M. Perkeybile, William M. Kenkel, Jason R. Yee, Craig F. Ferris, C. Sue Carter, Jessica J. Connelly
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
The neurohormone oxytocin regulates many aspects of physiology primarily by binding to its receptor, the oxytocin receptor. The oxytocin receptor gene (Oxtr) has been shown to have alternative transcripts in the mouse brain which may each have differ
Externí odkaz:
https://doaj.org/article/d830f27abe7e4a6f9d68155600d19e4d
Autor:
Brittany M. Brems, Erin E. Sullivan, Jenna G. Connolly, Jingchun Zhang, Arnold Chang, Richard Ortiz, Lucas Cantwell, Praveen Kulkarni, Ganesh A. Thakur, Craig F. Ferris
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
BackgroundAlpha 7 nicotinic acetylcholine receptor (α7nAChR) agonists have been developed to treat schizophrenia but failed in clinical trials due to rapid desensitization. GAT107, a type 2 allosteric agonist-positive allosteric modulator (ago-PAM)
Externí odkaz:
https://doaj.org/article/0eedf5d674d74d6d9c71bd536849d86c
Autor:
Katrina A. Milbocker, Gillian L. LeBlanc, Eric K. Brengel, Khan S. Hekmatyar, Praveen Kulkarni, Craig F. Ferris, Anna Y. Klintsova
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract 1 in 20 live births in the United States is affected by prenatal alcohol exposure annually, creating a major public health crisis. The teratogenic impact of alcohol on physical growth, neurodevelopment, and behavior is extensive, together re
Externí odkaz:
https://doaj.org/article/d6b896fd23f341a3bd3416cf82f2b2a8
Autor:
Autumn Taylor, Amanda Nweke, Veniesha Vincent, Marvellous Oke, Praveen Kulkarni, Craig F. Ferris
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionThe medical and recreational use of cannabis has increased in the United States. Its chronic use can have detrimental effects on the neurobiology of the brain—effects that are age-dependent. This was an exploratory study looking at the
Externí odkaz:
https://doaj.org/article/6bec4c6464834fe0b2496abffeae1113
Autor:
Aymen H. Sadaka, Justin Canuel, Marcelo Febo, Clare T. Johnson, Heather B. Bradshaw, Richard Ortiz, Federica Ciumo, Praveen Kulkarni, Michael A. Gitcho, Craig F. Ferris
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
With the recent legalization of inhaled cannabis for medicinal and recreational use, the elderly represents one of the newest, rapidly growing cohorts of cannabis users. To understand the neurobiological effects of cannabis on the aging brain, 19–2
Externí odkaz:
https://doaj.org/article/1339d5ce7288463dbaddb5836778a52b
Autor:
Kyrsten Kawazoe, Ryan McGlynn, Wilder Felix, Raquel Sevilla, Siyang Liao, Praveen Kulkarni, Craig F. Ferris
Publikováno v:
Pharmacology Research & Perspectives, Vol 10, Iss 6, Pp n/a-n/a (2022)
Abstract Pharmacological magnetic resonance imaging (phMRI) is a noninvasive method used to evaluate neural circuitry involved in the behavioral effects of drugs like ketamine, independent of their specific biochemical mechanism. The study was design
Externí odkaz:
https://doaj.org/article/8977485ec4d34f588924c641da1b41f8
Autor:
Aymen H. Sadaka, Ana G. Ozuna, Richard J. Ortiz, Praveen Kulkarni, Clare T. Johnson, Heather B. Bradshaw, Bruce S. Cushing, Ai-Ling Li, Andrea G. Hohmann, Craig F. Ferris
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-16 (2021)
Abstract Background The phytocannabinoid cannabidiol (CBD) exhibits anxiolytic activity and has been promoted as a potential treatment for post-traumatic stress disorders. How does CBD interact with the brain to alter behavior? We hypothesized that C
Externí odkaz:
https://doaj.org/article/f485f7eb3333468a9b1e8597a6b74aad
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 149, Iss , Pp 112812- (2022)
The clinical translation of therapeutic approaches to combat debilitating neurodegenerative conditions, such as Parkinson’s disease (PD), remains as an urgent unmet challenge. The strong molecular association between the pathogenesis of traumatic b
Externí odkaz:
https://doaj.org/article/a3c79f101bb743e79196f1d57ff721d6