Democratizing clinical-genomic data: How federated platforms can promote benefits sharing in genomics

Autor: Maria Alvarellos, Hadley E. Sheppard, Ingrid Knarston, Craig Davison, Nathaniel Raine, Thorben Seeger, Pablo Prieto Barja, Maria Chatzou Dunford

Publikováno v: Frontiers in Genetics, Vol 13 (2023)

Since the first sequencing of the human genome, associated sequencing costs have dramatically lowered, leading to an explosion of genomic data. This valuable data should in theory be of huge benefit to the global community, although unfortunately the

Externí odkaz: https://doaj.org/article/08b7881899a04f7ab532e867196c032e

Targeting nucleotide metabolism enhances the efficacy of anthracyclines and anti-metabolites in triple-negative breast cancer

Autor: Kylie A. McLaughlin, Karl Mulligan, Xanthi Stachtea, Robbie Carson, Melanie McKechnie, Richard H. Wilson, Vivien E. Prise, Melissa J. LaBonte, Roisin Morelli, Peter M. Wilson, Kienan Savage, Robert D. Ladner, Craig Davison, Catherine Knowlson

Publikováno v: npj Breast Cancer, Vol 7, Iss 1, Pp 1-13 (2021)
Davison, C, Ladner, R, Morelli, R, Knowlson, C, McKechnie, M, Carson, R, McLaughlin, K, Prise, V, Stachtea, X, Savage, K, Wilson, R, Mulligan, K, Wilson, P & LaBonte Wilson, M 2021, ' Targeting nucleotide metabolism enhances the efficacy of anthracyclines and anti-metabolites in triple-negative breast cancer ', npj Breast Cancer, vol. 7, 38, pp. 3 . https://doi.org/10.1038/s41523-021-00245-5
NPJ Breast Cancer

Triple-negative breast cancer (TNBC) remains the most lethal breast cancer subtype with poor response rates to the current chemotherapies and a lack of additional effective treatment options. We have identified deoxyuridine 5′-triphosphate nucleoti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61cf801a8def1f526ad1626d8fea4563
https://doaj.org/article/d3cd97feebf847539e7f6183d26a60c8

Naturally aspirating isokinetic total water content probe: Preliminary test results and design modifications

Autor: Craig Davison, James MacLeod, Thomas Ratvasky

A total water content probe for flight and ground based testing is under development. During operation across a range of altitudes and water content conditions the probe has to maintain isokinetic flow and vaporize the solid and liquid water content.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f178d5f4d4d69ec92b9fdb5eb5965a68
https://nrc-publications.canada.ca/eng/view/object/?id=0907f7e7-7a92-4c48-88d3-73e474cc67c9