Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Craig D. Peacock"'
Autor:
W. Dean Pontius, Ellen S. Hong, Zachary J. Faber, Jeremy Gray, Craig D. Peacock, Ian Bayles, Katreya Lovrenert, Diana H. Chin, Berkley E. Gryder, Cynthia F. Bartels, Peter C. Scacheri
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The metastasis-invasion cascade describes the series of steps required for a cancer cell to successfully spread from its primary tumor and ultimately grow within a secondary organ. Despite metastasis being a dynamic, multistep process, most
Externí odkaz:
https://doaj.org/article/6bb55550fb1640888f084ae083dc4872
Autor:
Priyanka Gopal, Elif Irem Sarihan, Eui Kyu Chie, Gwendolyn Kuzmishin, Semihcan Doken, Nathan A. Pennell, Daniel P. Raymond, Sudish C. Murthy, Usman Ahmad, Siva Raja, Francisco Almeida, Sonali Sethi, Thomas R. Gildea, Craig D. Peacock, Drew J. Adams, Mohamed E. Abazeed
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
BRAF mutations are frequent events in many different cancer types. Here, the authors highlight how distinct BRAF mutations affect the clonal dynamics and architecture of emergent tumours, with potential implications for therapeutic intervention.
Externí odkaz:
https://doaj.org/article/f366c71ec9404be4b753b8be5ed59abb
Autor:
Brian D. Yard, Drew J. Adams, Eui Kyu Chie, Pablo Tamayo, Jessica S. Battaglia, Priyanka Gopal, Kevin Rogacki, Bradley E. Pearson, James Phillips, Daniel P. Raymond, Nathan A. Pennell, Francisco Almeida, Jaime H. Cheah, Paul A. Clemons, Alykhan Shamji, Craig D. Peacock, Stuart L. Schreiber, Peter S. Hammerman, Mohamed E. Abazeed
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
The variability in patient response to radiation treatment is difficult to predict. Here, using more than 500 cell lines the authors measure response to radiation exposure and a large panel of compounds, and show that response can be predicted by gen
Externí odkaz:
https://doaj.org/article/877ae97e5e624e97832802165a437654
Autor:
D. Neil Watkins, Craig D. Peacock, Marion Dorsch, Giovanni Parmigiani, Rex Yung, Charles M. Rudin, Wendy L. Devereux, Jonathan T. Rhodes, Jared S. Hierman, Luigi Marchionni, Vincent C. Daniel
Supplemental Information from A Primary Xenograft Model of Small-Cell Lung Cancer Reveals Irreversible Changes in Gene Expression Imposed by Culture In vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa899c559e970b8cc9571ab9c24442a
https://doi.org/10.1158/0008-5472.22380123
https://doi.org/10.1158/0008-5472.22380123
Autor:
D. Neil Watkins, Craig D. Peacock, Marion Dorsch, Giovanni Parmigiani, Rex Yung, Charles M. Rudin, Wendy L. Devereux, Jonathan T. Rhodes, Jared S. Hierman, Luigi Marchionni, Vincent C. Daniel
Supplemental Tables A-H from A Primary Xenograft Model of Small-Cell Lung Cancer Reveals Irreversible Changes in Gene Expression Imposed by Culture In vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b527451a5ec0ea9a2b83050d038edfa8
https://doi.org/10.1158/0008-5472.22380120.v1
https://doi.org/10.1158/0008-5472.22380120.v1
Autor:
D. Neil Watkins, Craig D. Peacock, Marion Dorsch, Giovanni Parmigiani, Rex Yung, Charles M. Rudin, Wendy L. Devereux, Jonathan T. Rhodes, Jared S. Hierman, Luigi Marchionni, Vincent C. Daniel
Traditional approaches to the preclinical investigation of cancer therapies rely on the use of established cell lines maintained in serum-based growth media. This is particularly true of small-cell lung cancer (SCLC), where surgically resected tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003b1745e052de1079deff392fd23442
https://doi.org/10.1158/0008-5472.c.6499458.v1
https://doi.org/10.1158/0008-5472.c.6499458.v1
Autor:
Priyanka Gopal, Aaron Petty, Kevin Rogacki, Titas Bera, Rohan Bareja, Craig D. Peacock, Mohamed E. Abazeed
Publikováno v:
Science Advances. 8
Studies to date have not resolved how diverse transcriptional programs contribute to the intratumoral heterogeneity of small cell lung carcinoma (SCLC), an aggressive tumor associated with a dismal prognosis. Here, we identify distinct and commutable
Autor:
Jason Y. Park, Craig D. Peacock, Ankur S. Bhagwath, Elizabeth A. Montgomery, Wei Zhang, Thai H. Pham, Arlene A. Forastiere, Peiguo Ding, Brandi L. Cantarel, Jared S. Hiermann, David H. Wang, Taylor A. Williams, Chunfa Jie, D. Neil Watkins
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology
Gastroesophageal junction (GEJ) cancer remains a clinically significant disease in Western countries due to its increasing incidence, which mirrors that of esophageal cancer, and poor prognosis. To develop novel and effective approaches for preventio
Autor:
Sonali Sethi, Thomas R. Gildea, Sudish C. Murthy, Elif Irem Sarihan, Mohamed E. Abazeed, Priyanka Gopal, Francisco A. Almeida, Drew J. Adams, Gwendolyn B. Kuzmishin, Siva Raja, Eui Kyu Chie, Usman Ahmad, Craig D. Peacock, Daniel P. Raymond, Nathan A. Pennell, Semihcan Doken
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
Molecular determinants governing the evolution of tumor subclones toward phylogenetic branches or fixation remain unknown. Using sequencing data, we model the propagation and selection of clones expressing distinct categories of BRAF mutations to est
Autor:
Craig D. Peacock, Jyoti D. Patel, A. Petty, Rohan Bareja, Kevin Rogacki, Priyanka Gopal, Mohamed E. Abazeed, Titas Bera
Publikováno v:
Journal of Clinical Oncology. 39:e20587-e20587
e20587 Background: Small cell lung carcinoma (SCLC) is an aggressive, tobacco-associated tumor with neuroendocrine features characterized by rapid growth, metastatic progression, and initial response followed by almost invariable resistance to therap