Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Craig C Garner"'
Autor:
Ryan T Terry-Lorenzo, Viviana I Torres, Dhananjay Wagh, Jose Galaz, Selene K Swanson, Laurence Florens, Michael P Washburn, Clarissa L Waites, Eckart D Gundelfinger, Richard J Reimer, Craig C Garner
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167535 (2016)
Synaptic vesicles (SVs) fuse with the plasma membrane at a precise location called the presynaptic active zone (AZ). This fusion is coordinated by proteins embedded within a cytoskeletal matrix assembled at the AZ (CAZ). In the present study, we have
Externí odkaz:
https://doaj.org/article/c98af2f3e56245ee872e4c61b972e3f2
Autor:
Dhananjay Wagh, Ryan Terry-Lorenzo, Clarissa L Waites, Sergio A Leal-Ortiz, Christoph Maas, Richard J Reimer, Craig C Garner
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0120093 (2015)
The dynamic assembly of filamentous (F) actin plays essential roles in the assembly of presynaptic boutons, the fusion, mobilization and recycling of synaptic vesicles (SVs), and presynaptic forms of plasticity. However, the molecular mechanisms that
Externí odkaz:
https://doaj.org/article/a3bd617a5a7a4c298d15135015a81ac9
Autor:
Andreas M Grabrucker, Craig C Garner, Tobias M Boeckers, Lucia Bondioli, Barbara Ruozi, Flavio Forni, Maria Angela Vandelli, Giovanni Tosi
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17851 (2011)
Intact synaptic function and plasticity are fundamental prerequisites to a healthy brain. Therefore, synaptic proteins are one of the major targets for drugs used as neuro-chemical therapeutics. Unfortunately, the majority of drugs is not able to cro
Externí odkaz:
https://doaj.org/article/510e4c6e982f47859bd67adfc14b1978
Autor:
Daniela C Dieterich, Anna Karpova, Marina Mikhaylova, Irina Zdobnova, Imbritt König, Marco Landwehr, Martin Kreutz, Karl-Heinz Smalla, Karin Richter, Peter Landgraf, Carsten Reissner, Tobias M Boeckers, Werner Zuschratter, Christina Spilker, Constanze I Seidenbecher, Craig C Garner, Eckart D Gundelfinger, Michael R Kreutz
Publikováno v:
PLoS Biology, Vol 7, Iss 1 (2009)
Externí odkaz:
https://doaj.org/article/4f9b658cc9834481a7e4da24cc1a4de6
Autor:
Daniela C Dieterich, Anna Karpova, Marina Mikhaylova, Irina Zdobnova, Imbritt König, Marco Landwehr, Martin Kreutz, Karl-Heinz Smalla, Karin Richter, Peter Landgraf, Carsten Reissner, Tobias M Boeckers, Werner Zuschratter, Christina Spilker, Constanze I Seidenbecher, Craig C Garner, Eckart D Gundelfinger, Michael R Kreutz
Publikováno v:
PLoS Biology, Vol 6, Iss 2, p e34 (2008)
NMDA (N-methyl-D-aspartate) receptors and calcium can exert multiple and very divergent effects within neuronal cells, thereby impacting opposing occurrences such as synaptic plasticity and neuronal degeneration. The neuronal Ca2+ sensor Caldendrin i
Externí odkaz:
https://doaj.org/article/a0a50d7c19d1428e9dbed171236920de
Autor:
Shlomo Tsuriel, Ran Geva, Pedro Zamorano, Thomas Dresbach, Tobias Boeckers, Eckart D Gundelfinger, Craig C Garner, Noam E Ziv
Publikováno v:
PLoS Biology, Vol 4, Iss 9, p e271 (2006)
Recent studies suggest that central nervous system synapses can persist for weeks, months, perhaps lifetimes, yet little is known as to how synapses maintain their structural and functional characteristics for so long. As a step toward a better under
Externí odkaz:
https://doaj.org/article/4196b2ac41d940fd9a9c50c11290575c
Autor:
Kazi Atikur Rahman, Marta Orlando, Ayub Boulos, Ewa Andrzejak, Dietmar Schmitz, Noam E. Ziv, Harald Prüss, Craig C. Garner, Aleksandra Ichkova
Publikováno v:
Glia 71(8), 1804-1829 (2023). doi:10.1002/glia.24369
Autoantibodies against the NR1 subunit of NMDA receptors (NMDARs) have been shown to promote crosslinking and internalization of bound receptors in NMDAR encephalitis (NMDARE). This internalization-mediated loss of NMDARs is thought to be the major m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d8d6f8e0d34ad5737928bf90219510
Autor:
Ewa Andrzejak, Eshed Rabinovitch, Jakob Kreye, Harald Prüss, Christian Rosenmund, Noam E. Ziv, Craig C. Garner, Frauke Ackermann
Publikováno v:
The journal of neuroscience 42(15), 3253-3270 (2022). doi:10.1523/JNEUROSCI.1689-21.2022
Anti-NMDA receptor (NMDAR) encephalitis is a severe neuropsychiatric disorder associated with autoantibodies against NMDARs, which cause a variety of symptoms from prominent psychiatric and cognitive manifestations to seizures and autonomic instabili
Autor:
Susann Michanski, Rohan Kapoor, Anna M. Steyer, Wiebke Möbius, Iris Früholz, Frauke Ackermann, Mehmet Gültas, Craig C. Garner, F. Kent Hamra, Jakob Neef, Nicola Strenzke, Tobias Moser, Carolin Wichmann
Cochlear inner hair cells (IHCs) form specialized ribbon synapses with spiral ganglion neurons that tireless-ly transmit sound information at high rates over long time periods with extreme temporal precision. This functional specialization is essenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83e490193e2a19496dcc0b87673caf36
https://doi.org/10.1101/2022.12.15.520589
https://doi.org/10.1101/2022.12.15.520589
Autor:
Adriana C M, van Casteren, Frauke, Ackermann, Kazi Atikur, Rahman, Ewa, Andrzejak, Christian, Rosenmund, Jakob, Kreye, Harald, Prüss, Craig C, Garner, Aleksandra, Ichkova
Publikováno v:
eNeuro. 9(6)
Autoantibodies against central nervous system proteins are increasingly being recognized in association with neurologic disorders. Although a growing number of neural autoantibodies have been identified, a causal link between specific autoantibodies