Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Craig Blanchette"'
Autor:
Siri Tähtinen, Ira Mellman, Christopher Kemball, Diamanda Rigas, Emily Freund, Rebecca Leylek, Ann-Jay Tong, Anna-Maria Herzner, Shirley Ng Palace, Sara Wichner, Craig Blanchette, Benjamin Haley, Lélia Delamarre
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/522169f677fe4b9e8b745e56c64817bb
Autor:
David G. Coffey, Yuexin Xu, Andrea M. H. Towlerton, Marcin Kowanetz, Priti Hegde, Martine Darwish, Mahesh Yadav, Craig Blanchette, Shannon M. Ruppert, Sarah Bertino, Qikai Xu, Andrew Ferretti, Adam Weinheimer, Matthew Hellmann, Angel Qin, Dafydd Thomas, Edus H. Warren, Nithya Ramnath
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Most patients with advanced non-small cell lung cancer (NSCLC) do not achieve a durable remission after treatment with immune checkpoint inhibitors. Here we report the clinical history of an exceptional responder to radiation and anti-program death-l
Externí odkaz:
https://doaj.org/article/0ad62252e9ae47dfa7add7911dd39d72
Autor:
Yu Kong, Christopher M. Rose, Ashley A. Cass, Alexander G. Williams, Martine Darwish, Steve Lianoglou, Peter M. Haverty, Ann-Jay Tong, Craig Blanchette, Matthew L. Albert, Ira Mellman, Richard Bourgon, John Greally, Suchit Jhunjhunwala, Haiyin Chen-Harris
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Treatment with demethylation agents can reactivate transposable elements. Here in glioblastoma, the authors also show that this is accompanied by de novo presentation of TE-derived peptides on MHC class I molecules.
Externí odkaz:
https://doaj.org/article/4f372d927b9744d19d8bbddc89834da4
Autor:
Whitney Shatz, Philip E Hass, Nikhil Peer, Maciej T Paluch, Craig Blanchette, Guanghui Han, Wendy Sandoval, Ashley Morando, Kelly M Loyet, Vladimir Bantseev, Helen Booler, Susan Crowell, Amrita Kamath, Justin M Scheer, Robert F Kelley
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218613 (2019)
Innovative protein engineering and chemical conjugation technologies have yielded an impressive number of drug candidates in clinical development including >80 antibody drug conjugates, >60 bispecific antibodies, >35 Fc-fusion proteins and >10 immuno
Externí odkaz:
https://doaj.org/article/82a56a7b258c43e885de3b136fc2e95b
Autor:
Nadeen O Chahine, Craig Blanchette, Cynthia B Thomas, Jeffrey Lu, Dominik Haudenschild, Gabriela G Loots
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61651 (2013)
Articular cartilage chondrocytes are responsible for the synthesis, maintenance, and turnover of the extracellular matrix, metabolic processes that contribute to the mechanical properties of these cells. Here, we systematically evaluated the effect o
Externí odkaz:
https://doaj.org/article/f9423bf3c95844aba1718cf1c72803c0
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42116 (2012)
Enzyme catalyzed conversion of plant biomass to sugars is an inherently inefficient process, and one of the major factors limiting economical biofuel production. This is due to the physical barrier presented by polymers in plant cell walls, including
Externí odkaz:
https://doaj.org/article/2fc18379e84343b980b81edccef55667
Autor:
Rich Rochford, Craig Blanchette
Publikováno v:
IMAPSource Proceedings. 2022
High value devices used in microwave modules and other microelectronic assemblies have become increasingly thin and susceptible to “Component Out Of Pocket” (COOP) conditions that can occur during packaging, shipping, and customer handling. This
Autor:
Siri Tahtinen, Ann-Jay Tong, Patricia Himmels, Jaehak Oh, Andres Paler-Martinez, Leesun Kim, Sara Wichner, Yoko Oei, Mark J. McCarron, Emily C. Freund, Zhainib Adel Amir, Cecile C. de la Cruz, Benjamin Haley, Craig Blanchette, Jill M. Schartner, Weilan Ye, Mahesh Yadav, Ugur Sahin, Lélia Delamarre, Ira Mellman
Publikováno v:
Nature Immunology. 23:532-542
The use of lipid-formulated RNA vaccines for cancer or COVID-19 is associated with dose-limiting systemic inflammatory responses in humans that were not predicted from preclinical studies. Here, we show that the 'interleukin 1 (IL-1)-interleukin 1 re
Autor:
Hem Gurung, Amy Heidersbach, Martine Darwish, Pamela Chan, Jenny Li, Maureen Beresini, Oliver Zill, Andrew Wallace, Ann-Jay Tong, Dan Hascall, Eric Torres, Andy Chang, Kenny 'Hei-Wai' Lou, Yassan Abdolazimi, Amanda Moore, Uzodinma Uche, Melanie Laur, Richard Notturno, Peter J.R. Ebert, Craig Blanchette, Benjamin Haley, Christopher M. Rose
SummaryStrategies for maximizing the potency and specificity of cancer immunotherapies have sparked efforts to identify recurrent epitopes presented in the context of defined tumor-associated neoantigens. Discovering these “neoepitopes” can be di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6317922554eb98fcf714d679f289ec76
https://doi.org/10.1101/2022.10.27.513529
https://doi.org/10.1101/2022.10.27.513529
Autor:
Luis F. Schachner, Wilson Phung, Guanghui Han, Martine Darwish, Ashley Bell, J. Scott Mellors, Kristina Srzentic, Romain Huguet, Craig Blanchette, Wendy Sandoval
Publikováno v:
Analytical chemistry. 94(42)
Immune monitoring in cancer immunotherapy involves screening CD8+ T-cell responses against neoantigens, the tumor-specific peptides presented by Major histocompatibility complex Class I (MHCI) on the cell surface. High-throughput immune monitoring re