Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Craig B. Wilen"'
Autor:
Jonathan D. Lee, Bridget L. Menasche, Maria Mavrikaki, Madison M. Uyemura, Su Min Hong, Nina Kozlova, Jin Wei, Mia M. Alfajaro, Renata B. Filler, Arne Müller, Tanvi Saxena, Ryan R. Posey, Priscilla Cheung, Taru Muranen, Yujing J. Heng, Joao A. Paulo, Craig B. Wilen, Frank J. Slack
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113478- (2023)
Summary: Coronavirus disease 2019 (COVID-19) remains a significant public health threat due to the ability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants to evade the immune system and cause breakthrough infections. Although
Externí odkaz:
https://doaj.org/article/fc5e40c8967549f19441624446c62419
Autor:
Shivali Patel, Alec N. Sexton, Madison S. Strine, Craig B. Wilen, Matthew D. Simon, Anna Marie Pyle
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Compact RNA structural motifs control many aspects of gene expression, but we lack methods for finding these structures in the vast expanse of multi-kilobase RNAs. To adopt specific 3-D shapes, many RNA modules must compress their RNA backbo
Externí odkaz:
https://doaj.org/article/222cbbdf4c56429296e795df9d118c31
Autor:
Sarah Lapidus, Feimei Liu, Arnau Casanovas-Massana, Yile Dai, John D. Huck, Carolina Lucas, Jon Klein, Renata B. Filler, Madison S. Strine, Mouhamad Sy, Awa B. Deme, Aida S. Badiane, Baba Dieye, Ibrahima Mbaye Ndiaye, Younous Diedhiou, Amadou Moctar Mbaye, Cheikh Tidiane Diagne, Inés Vigan-Womas, Alassane Mbengue, Bacary D. Sadio, Moussa M. Diagne, Adam J. Moore, Khadidiatou Mangou, Fatoumata Diallo, Seynabou D. Sene, Mariama N. Pouye, Rokhaya Faye, Babacar Diouf, Nivison Nery, Federico Costa, Mitermayer G. Reis, M. Catherine Muenker, Daniel Z. Hodson, Yannick Mbarga, Ben Z. Katz, Jason R. Andrews, Melissa Campbell, Ariktha Srivathsan, Kathy Kamath, Elisabeth Baum-Jones, Ousmane Faye, Amadou Alpha Sall, Juan Carlos Quintero Vélez, Michael Cappello, Michael Wilson, Choukri Ben-Mamoun, Richard Tedder, Myra McClure, Peter Cherepanov, Fabrice A. Somé, Roch K. Dabiré, Carole Else Eboumbou Moukoko, Jean Bosco Ouédraogo, Yap Boum, John Shon, Daouda Ndiaye, Adam Wisnewski, Sunil Parikh, Akiko Iwasaki, Craig B. Wilen, Albert I. Ko, Aaron M. Ring, Amy K. Bei
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Sero-surveillance can monitor and project disease burden and risk. However, SARS-CoV-2 antibody test results can produce false positive results, limiting their efficacy as a sero-surveillance tool. False positive SARS-CoV-2 antibody results
Externí odkaz:
https://doaj.org/article/e3f6d23d2b9d49268212f6f24423baf3
Autor:
Zhenhao Fang, Lei Peng, Carolina Lucas, Qianqian Lin, Liqun Zhou, Luojia Yang, Yanzhi Feng, Ping Ren, Paul A. Renauer, Valter S. Monteiro, Anne M. Hahn, Jonathan J. Park, Xiaoyu Zhou, Yale SARS-CoV-2 Genomic Surveillance Initiative, Nathan D. Grubaugh, Craig B. Wilen, Sidi Chen
Publikováno v:
Cell Discovery, Vol 8, Iss 1, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/c41d5e966f5b48f08c927fe555b2220e
Autor:
Zhenhao Fang, Lei Peng, Renata Filler, Kazushi Suzuki, Andrew McNamara, Qianqian Lin, Paul A. Renauer, Luojia Yang, Bridget Menasche, Angie Sanchez, Ping Ren, Qiancheng Xiong, Madison Strine, Paul Clark, Chenxiang Lin, Albert I. Ko, Nathan D. Grubaugh, Craig B. Wilen, Sidi Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Here the authors show that Omicron neutralizing antibody titers decline over time in mice immunized with a wild-type (WT) lipid nanoparticle (LNP)-mRNA vaccine and are robustly increased by WT or Omicron LNP-mRNA and that Omicron boosters elicit high
Externí odkaz:
https://doaj.org/article/642217d7e3b74518923f116fe43d0f0a
Autor:
Shiv Gandhi, Jonathan Klein, Alexander J. Robertson, Mario A. Peña-Hernández, Michelle J. Lin, Pavitra Roychoudhury, Peiwen Lu, John Fournier, David Ferguson, Shah A. K. Mohamed Bakhash, M. Catherine Muenker, Ariktha Srivathsan, Elsio A. Wunder, Nicholas Kerantzas, Wenshuai Wang, Brett Lindenbach, Anna Pyle, Craig B. Wilen, Onyema Ogbuagu, Alexander L. Greninger, Akiko Iwasaki, Wade L. Schulz, Albert I. Ko
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Here, the authors identify and validate the emergence of a SARS-CoV-2 resistance mutation to Remdesivir, associated with virological recrudesce in an immunocompromised patient with persistent COVID-19.
Externí odkaz:
https://doaj.org/article/9b3a77f831774145b06a422bbfb8f3de
Autor:
Lei Peng, Yingxia Hu, Madeleine C. Mankowski, Ping Ren, Rita E. Chen, Jin Wei, Min Zhao, Tongqing Li, Therese Tripler, Lupeng Ye, Ryan D. Chow, Zhenhao Fang, Chunxiang Wu, Matthew B. Dong, Matthew Cook, Guilin Wang, Paul Clark, Bryce Nelson, Daryl Klein, Richard Sutton, Michael S. Diamond, Craig B. Wilen, Yong Xiong, Sidi Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Despite effective vaccines against SARS-CoV-2, therapeutic options such as anti-virals and neutralizing antibodies are critical in treating disease, especially given the breakthrough infections of emerging VOCs. Here, Peng et al. generate two potent
Externí odkaz:
https://doaj.org/article/3c2da467436042e1868fd384b454c96c
Autor:
Isabel M. Ott, Madison S. Strine, Anne E. Watkins, Maikel Boot, Chaney C. Kalinich, Christina A. Harden, Chantal B.F. Vogels, Arnau Casanovas-Massana, Adam J. Moore, M. Catherine Muenker, Maura Nakahata, Maria Tokuyama, Allison Nelson, John Fournier, Santos Bermejo, Melissa Campbell, Rupak Datta, Charles S. Dela Cruz, Shelli F. Farhadian, Albert I. Ko, Akiko Iwasaki, Nathan D. Grubaugh, Craig B. Wilen, Anne L. Wyllie
Publikováno v:
Emerging Infectious Diseases, Vol 27, Iss 4, Pp 1146-1150 (2021)
The expense of saliva collection devices designed to stabilize severe acute respiratory syndrome coronavirus 2 RNA is prohibitive to mass testing. However, virus RNA in nonsupplemented saliva is stable for extended periods and at elevated temperature
Externí odkaz:
https://doaj.org/article/668ee32171334b1b96788cdfb6bbe329
Autor:
Madison S. Strine, Craig B. Wilen
Publikováno v:
PLoS Pathogens, Vol 18, Iss 3 (2022)
Although tuft cells were discovered over 60 years ago, their functions have long been enigmatic, especially in human health. Nonetheless, tuft cells have recently emerged as key orchestrators of the host response to diverse microbial infections in th
Externí odkaz:
https://doaj.org/article/e7b65623e6564ea182d8a5db310f6af6
Autor:
Paula Ortega-Gonzalez, Gwen Taylor, Rohit K. Jangra, Raquel Tenorio, Isabel Fernandez de Castro, Bernardo A. Mainou, Robert C. Orchard, Craig B. Wilen, Pamela H. Brigleb, Jorna Sojati, Kartik Chandran, Martin Sachse, Cristina Risco, Terence S. Dermody
Publikováno v:
PLoS Pathogens, Vol 18, Iss 3 (2022)
Cholesterol homeostasis is required for the replication of many viruses, including Ebola virus, hepatitis C virus, and human immunodeficiency virus-1. Niemann-Pick C1 (NPC1) is an endosomal-lysosomal membrane protein involved in cholesterol trafficki
Externí odkaz:
https://doaj.org/article/0cec75b1fda54dfcb4fc3caf782c39b8