Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Craig B. Clark"'
Autor:
Evelyn M. Horn, Craig B. Clark
Publikováno v:
Cardiology Clinics. 34:401-411
Pulmonary hypertension from left heart disease (PH-LHD) is the most common form of PH, defined as mean pulmonary artery pressure ≥25 mm Hg and pulmonary artery wedge pressure ≥15 mm Hg. PH-LHD development is associated with more severe left-sided
Publikováno v:
Echocardiography. 33:1195-1201
Background In patients with atrial fibrillation or flutter, a left atrial appendage ejection velocity measured via transesophageal echocardiography equal to or less than 40 cm/sec has been shown to correlate with an increased risk of developing left
Autor:
Craig B, Clark, Evelyn M, Horn
Publikováno v:
Cardiology clinics. 34(3)
Pulmonary hypertension from left heart disease (PH-LHD) is the most common form of PH, defined as mean pulmonary artery pressure ≥25 mm Hg and pulmonary artery wedge pressure ≥15 mm Hg. PH-LHD development is associated with more severe left-sided
Publikováno v:
Experimental Cell Research. 292:265-273
Mechanical stimulation has been proposed as a fundamental determinant of muscle physiology. The mechanotransduction of strain and strain rate in C2C12 myoblasts were investigated utilizing a radiolabeled GTP analogue to detect stretch-induced GTP-bin
Publikováno v:
Biochemical and Biophysical Research Communications. 299:258-262
The endothelium is known to sense and respond to its physical environment, but the underlying mechanisms and early events of endothelial cell mechanotransduction are not well understood. The present study measured G protein activation by mechanical s
Autor:
Gudjon Karlsson, Yi Zhang, M. Bridget Zimmerman, Craig B. Clark, Richard E. Kerber, L.Ray Davies
Publikováno v:
Resuscitation. 54:281-287
Transthoracic impedance and current flow are determinants of defibrillation success with monophasic shocks. Whether transthoracic impedance, either independently or via its association with body weight, is a determinant of biphasic waveform shock suc
Publikováno v:
Review of Scientific Instruments. 72:2415-2422
Cells are able to sense and respond to mechanical strain both in vivo and in vitro, and though the ability of strain to stimulate intracellular biochemical events is well established, the influence of the rate at which these strains are applied has n
Publikováno v:
Circulation Research. 79:834-839
Fluid shear stimulates endothelial cells, with the external hemodynamic forces transduced across the plasma membrane to modulate intracellular events. We report the first direct evidence that identifies specific GTP binding proteins (G proteins) acti
Publikováno v:
Biochemical and Biophysical Research Communications. 224:660-665
We propose that fluid shear presents two distinct stimuli to endothelium—the rate of change of flow and flow itself, to which cells sense and respond via independent mechanochemical transduction pathways. We demonstrate that nitric oxide production
APTIMA PCA3 molecular urine test: development of a method to aid in the diagnosis of prostate cancer
Autor:
Maria Luz Macairan, Jeannette Mathis, Amy Blase, Michelle M.J. Cass, Ina L. Deras, Craig B. Clark, Troels Meyer, Harry G. Rittenhouse, Leonard S. Marks, Sharon Bodrug, Steven T. Brentano, Jimmykim Pham, Petrea Hodge, Sheila M.J. Aubin, Jack Groskopf
Publikováno v:
Clinical chemistry. 52(6)
Background: Prostate cancer gene 3 (PCA3) encodes a prostate-specific mRNA that has shown promise as a prostate cancer diagnostic tool. This report describes the characterization of a prototype quantitative PCA3-based test for whole urine. Methods: W