Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Craig B Bennett"'
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60909 (2013)
RNA polymerase II translocates across much of the genome and since it can be blocked by many kinds of DNA lesions, detects DNA damage proficiently; it thereby contributes to DNA repair and to normal levels of DNA damage resistance. However, the compo
Externí odkaz:
https://doaj.org/article/842d140183d0487fa03126abb5f4214f
Autor:
Tammy J Westmoreland, Sajith M Wickramasekara, Andrew Y Guo, Alice L Selim, Tiffany S Winsor, Arno L Greenleaf, Kimberly L Blackwell, John A Olson, Jeffrey R Marks, Craig B Bennett
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5830 (2009)
The chemotherapeutic doxorubicin (DOX) induces DNA double-strand break (DSB) damage. In order to identify conserved genes that mediate DOX resistance, we screened the Saccharomyces cerevisiae diploid deletion collection and identified 376 deletion st
Externí odkaz:
https://doaj.org/article/7e3c66acc2fb4792a627abbf418cf73e
Autor:
Craig B Bennett, Tammy J Westmoreland, Carmel S Verrier, Carrie A B Blanchette, Tiffany L Sabin, Hemali P Phatnani, Yuliya V Mishina, Gudrun Huper, Alice L Selim, Ernest R Madison, Dominique D Bailey, Adebola I Falae, Alvaro Galli, John A Olson, Arno L Greenleaf, Jeffrey R Marks
Publikováno v:
PLoS ONE, Vol 3, Iss 1, p e1448 (2008)
BRCA1 has been implicated in numerous DNA repair pathways that maintain genome integrity, however the function responsible for its tumor suppressor activity in breast cancer remains obscure. To identify the most highly conserved of the many BRCA1 fun
Externí odkaz:
https://doaj.org/article/4bc481118f46427cb111886447c1d4de
Autor:
Wilfred Saito, Tammy J. Westmoreland, Craig B. Bennett, John A. Olson, Jeffrey R. Marks, Gudrun Huper
Publikováno v:
Journal of Surgical Research. 113:62-73
Background Heterologous expression of the tumor suppressor BRCA1 in the yeast Saccharomyces cerevisiae is lethal. To identify potential new BRCA1-interacting gene targets, we characterized highly conserved ionizing radiation (IR) sensitive gene delet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97d83ecd114eddc1e8ffd21f1812d353
https://doi.org/10.1016/s0022-4804(03)00155-0
https://doi.org/10.1016/s0022-4804(03)00155-0
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60909 (2013)
PLoS ONE
PLoS ONE
RNA polymerase II translocates across much of the genome and since it can be blocked by many kinds of DNA lesions, detects DNA damage proficiently; it thereby contributes to DNA repair and to normal levels of DNA damage resistance. However, the compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52902c137863ff7b3cafc3d88da78d60
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23613755/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23613755/?tool=EBI
Autor:
Craig B. Bennett
Publisher Summary This chapter provides an introduction to the approaches adopted to identify genes required for DNA double-strand break damage signaling in the yeast Saccharomyces cerevisiae. The double strand breaks (DSB) can appear spontaneously o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19a6b50e7b825a91367678a3acbf93e4
https://doi.org/10.1016/b978-0-12-374145-5.00260-6
https://doi.org/10.1016/b978-0-12-374145-5.00260-6
Autor:
Craig B Bennett
We selected Saccharomyces cerevisiae mutants from the diploid deletion collection that suppressed Gi arrest and lethality following heterologous expression of BRCAl. Expression of BRCAl was confirmed by immunofluorescence or Western blot analysis. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa86fe341d23409217c1fa7e80e92688
https://doi.org/10.21236/ada437737
https://doi.org/10.21236/ada437737
Autor:
Jeffrey R. Marks, Michael A. Resnick, Craig B. Bennett, John A. Olson, Tammy J. Westmoreland, Eric M. Thompson
Publikováno v:
Eukaryotic cell. 3(2)
To identify new nonessential genes that affect genome integrity, we completed a screening for diploid mutant Saccharomyces cerevisiae strains that are sensitive to ionizing radiation (IR) and found 62 new genes that confer resistance. Along with thos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c35f684b92d1430c436bebffa9eeb52f
https://pubmed.ncbi.nlm.nih.gov/15075273
https://pubmed.ncbi.nlm.nih.gov/15075273
Autor:
Craig B. Bennett, Michael A. Resnick
Publikováno v:
Handbook of Cell Signaling
The total response of an organism to DNA perturbations is determined by many factors, including the nature of the lesions, ability to detect and tolerate the lesions, and status of the cell cycle at the time the damage occurs. The responses require t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac417af396c5ded0d656cffb6acb0866
https://doi.org/10.1016/b978-012124546-7/50664-1
https://doi.org/10.1016/b978-012124546-7/50664-1