Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Craig A. Ogle"'
Autor:
Shu-ta Wu, Anthony J. Fowler, Corey B. Garmon, Adam B. Fessler, Joshua D. Ogle, Kajal R. Grover, Bailey C. Allen, Chandra D. Williams, Ru Zhou, Mahboubeh Yazdanifar, Craig A. Ogle, Pinku Mukherjee
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-13 (2018)
Abstract Background Pancreatic ductal adenocarcinoma (PDA) remains the most aggressive cancers with a 5-year survival below 10%. Systemic delivery of chemotherapy drugs has severe side effects in patients with PDA and does not significantly improve o
Externí odkaz:
https://doaj.org/article/07bd40c201904f37a49e6060dca5f3bc
Publikováno v:
Acta Crystallographica Section E, Vol 66, Iss 9, Pp o2442-o2442 (2010)
The title compound, C44H60Si, was prepared as an internal standard for diffusion-ordered NMR spectroscopy. The Si atom lies on a special position with overline4 site symmetry.
Externí odkaz:
https://doaj.org/article/a3a8b160533f4a38aafcaf213382fdb8
Publikováno v:
Acta Crystallographica Section E, Vol 66, Iss 7, Pp o1678-o1678 (2010)
The title compound, C18H19NO4, was prepared as an indole derivative with possible antimitotic properties. The planes of the indole and trimethoxyphenyl rings make a dihedral angle of 45.35 (5)° with one another. In the crystal, molecules related by
Externí odkaz:
https://doaj.org/article/29ee04650f1a48ef9e45c8106ed4d3e5
Publikováno v:
Acta Crystallographica Section E, Vol 66, Iss 1, Pp o132-o132 (2010)
The title compound, C34H28Si, was prepared as an internal standard for diffusion-ordered NMR spectroscopy. The four ligands are arranged tetrahedrally around the Si atom. The two naphthalene systems are nearly perpendicular, making an angle of 86.42
Externí odkaz:
https://doaj.org/article/ba9045b07d2642cd9d46bf63aef5e177
Publikováno v:
Acta Crystallographica Section E, Vol 65, Iss 10, Pp o2353-o2353 (2009)
The title compound, C12H13NO4, was prepared as a precursor to an indole derivative with possible antimitotic properties. The molecule is very nearly planar; the maximum deviation of any non-H atom from the mean plane of the indole ring is 0.120 (3)
Externí odkaz:
https://doaj.org/article/9012b3a4b82b46009e4bfc3fe8d830c9
Publikováno v:
Acta Crystallographica Section E, Vol 64, Iss 7, Pp o1284-o1284 (2008)
The title compound, C12H8BrN, was prepared as a starting material for a Suzuki cross-coupling reaction with a pinacol ester. The torsion angle about the ring–methylene C—C bond is 30.7 (3)°, such that the N atom is displaced by 1.174 (4) Å from
Externí odkaz:
https://doaj.org/article/58715a240f1a42bc850270d17036f354
Publikováno v:
Bioconjugate Chemistry. 32:904-908
Isatoic anhydride (IA) has been shown to be a useful platform for quantifiable bioconjugation. The elaboration of a water-soluble isatoic anhydride-based platform with biotin offers readily quantifiable biotinylation reagents through nondestructive m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8f125b1bae2a5a936577b1155a88771
https://doi.org/10.1021/acs.bioconjchem.1c00150
https://doi.org/10.1021/acs.bioconjchem.1c00150
Autor:
Abhishek Dey, Adam B. Fessler, Anthony J. Fowler, Craig A. Ogle, Dominic S. Finis, Kausik Chakrabarti
Publikováno v:
Bioconjugate Chemistry. 31:884-888
1-Methyl-7-nitroisatoic anhydride (1M7) and 2-methylnicotinic acid imidazolide (NAI) are two of the most commonly applied RNA-SHAPE electrophiles; 1M7 due to its high reactivity and NAI for its solubility and cell permeability. While the addition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a221ad926a7b3c91c5b3961242f5a5c
https://doi.org/10.1021/acs.bioconjchem.0c00024
https://doi.org/10.1021/acs.bioconjchem.0c00024
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 49(6):e34. Oxford University Press
Nucleic Acids Research, 49(6):e34. Oxford University Press
Due to the mounting evidence that RNA structure plays a critical role in regulating almost any physiological as well as pathological process, being able to accurately define the folding of RNA molecules within living cells has become a crucial need.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c74f16e0521848cca4df578c5d6484b
https://doi.org/10.1101/2020.08.31.274761
https://doi.org/10.1101/2020.08.31.274761
Autor:
Adam B. Fessler, Dominic S. Finis, Anthony J. Fowler, Nemah-Allah Saleh, Daniel S. Jones, Abhishek Dey, Kausik Chakrabarti, Corey B. Garmon, Craig A. Ogle
Publikováno v:
Bioconjugate Chemistry. 29:3196-3202
N-(3-Iodopropyl)isatoic anhydride (IPIA) has been demonstrated to serve as an efficient substrate for the development of an extended bioconjugation platform. Derivatives of IPIA are water-soluble and adaptable and share a common chromophore, renderin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6b2f400cd1161ce3a279a69a7e311e2
https://doi.org/10.1021/acs.bioconjchem.8b00518
https://doi.org/10.1021/acs.bioconjchem.8b00518